EP0847528A1 - Magnetische nanopartikel gehoppelt an annexine und ihre verwendung - Google Patents
Magnetische nanopartikel gehoppelt an annexine und ihre verwendungInfo
- Publication number
- EP0847528A1 EP0847528A1 EP96922967A EP96922967A EP0847528A1 EP 0847528 A1 EP0847528 A1 EP 0847528A1 EP 96922967 A EP96922967 A EP 96922967A EP 96922967 A EP96922967 A EP 96922967A EP 0847528 A1 EP0847528 A1 EP 0847528A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- cells
- effector
- ffsh
- annexin
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/005—Pretreatment specially adapted for magnetic separation
- B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
- H01F1/44—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4718—Lipocortins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/823—Immunogenic carrier or carrier per se
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
- Y10S977/838—Magnetic property of nanomaterial
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/92—Detection of biochemical
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/927—Diagnostic contrast agent
- Y10S977/93—MRI contrast agent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
Definitions
- Anx FF particles of the invention can be used in the manufacture of a medicament intended to treat the immune deficiencies induced by viruses or parasites.
- Figure 4 Retention rate of erythrocytes by Anx FF as a function of the number of cells used in the test.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Power Engineering (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9507865 | 1995-06-29 | ||
FR9507865A FR2736197B1 (fr) | 1995-06-29 | 1995-06-29 | Nanoparticules magnetiques couplees a de l'annexine et leur utilisation |
PCT/FR1996/000964 WO1997001760A1 (fr) | 1995-06-29 | 1996-06-20 | Nanoparticules magnetiques couplees a de l'annexine et leur utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
EP0847528A1 true EP0847528A1 (de) | 1998-06-17 |
Family
ID=9480536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96922967A Withdrawn EP0847528A1 (de) | 1995-06-29 | 1996-06-20 | Magnetische nanopartikel gehoppelt an annexine und ihre verwendung |
Country Status (4)
Country | Link |
---|---|
US (1) | US6150181A (de) |
EP (1) | EP0847528A1 (de) |
FR (1) | FR2736197B1 (de) |
WO (1) | WO1997001760A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6284475B1 (en) * | 1997-07-11 | 2001-09-04 | Mount Sinai School Of Medicine Of The City Of New York | Assays for diagnosis of thrombophilic disease |
IL123429A0 (en) | 1998-02-24 | 1998-09-24 | Nst Neurosurvival Technologies | Peptides and pharmaceutical compositions comprising same |
IL125908A (en) | 1998-08-24 | 2005-05-17 | Nst Neurosurvival Technologies | Peptides and pharmaceutical compositions comprising same |
IL131266A0 (en) | 1999-08-05 | 2001-01-28 | N S T Neurosurvival Technologi | Peptides and pharmaceutical compositions comprising same |
CA2373355A1 (en) * | 1999-06-09 | 2000-12-21 | I.D.M. Immuno-Designed Molecules | New molecular complexes presenting high affinity binding with respect to monocyte derived cells and their uses in therapy |
US6623982B1 (en) * | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
US6562403B2 (en) * | 2001-10-15 | 2003-05-13 | Kansas State University Research Foundation | Synthesis of substantially monodispersed colloids |
SE0202725D0 (sv) * | 2002-09-12 | 2002-09-12 | Genovis Ab | Anordning för magnetiskt inducerbar membrantransport |
FR2848850B1 (fr) * | 2002-12-20 | 2005-06-24 | Guerbet Sa | Nouvelles compositions de particules magnetiques recouvertes de derives gem-bisphosphonates. |
WO2005016414A2 (en) * | 2003-08-13 | 2005-02-24 | The Children's Hospital Of Philadelphia | Use of receptor sequences for immobilizing gene vectors on surfaces |
JP4949041B2 (ja) * | 2003-12-18 | 2012-06-06 | マサチューセッツ インスティテュート オブ テクノロジー | 磁性ナノ粒子によって促進されたバイオプロセス |
US8293522B2 (en) * | 2004-05-13 | 2012-10-23 | Centre National De La Recherche Scientifique | Device for binding a target entity to a bait entity and detection methods using the same |
KR100604976B1 (ko) | 2004-09-03 | 2006-07-28 | 학교법인연세대학교 | 다작용기 리간드로 안정화된 수용성 나노입자 |
US7371327B2 (en) | 2005-03-04 | 2008-05-13 | Kenneth Cross | Device for the immobilization of nano- and micro-sized particles in a solid-fluid contact vessel facilitating mass-momentum, and heat-transport at the solid-fluid interfaces |
FR2921837B1 (fr) * | 2007-10-05 | 2015-07-31 | Guerbet Sa | Nouveau procede de preparation de nanoparticules recouvertes d'une couche stabilisatrice organique couplee a des ligands de ciblage |
EP3156078B1 (de) | 2009-04-10 | 2020-03-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Fucoidane als liganden zur diagnose degenerativer pathologien |
US9409148B2 (en) | 2013-08-08 | 2016-08-09 | Uchicago Argonne, Llc | Compositions and methods for direct capture of organic materials from process streams |
US9579623B2 (en) | 2013-11-23 | 2017-02-28 | Kenneth W. Cross | Specialized immobilization media |
CN112763703B (zh) * | 2020-12-31 | 2023-04-28 | 深圳天深医疗器械有限公司 | 一种免疫磁珠及其制备方法和应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1040817B (de) * | 1956-12-31 | 1958-10-09 | Leybolds Nachfolger E | Messsystem fuer Ionisationsmanometer |
US4920061A (en) * | 1984-03-02 | 1990-04-24 | The University Of Texas System | Biological magnetic colloids |
US5627036A (en) * | 1989-12-27 | 1997-05-06 | Boehringer Ingelheim International Gmbh | Use of an anticoagulant as a diagnostic agent |
DE4040817A1 (de) * | 1989-12-27 | 1991-07-04 | Boehringer Ingelheim Int | Verwendung eines antikoagulant als diagnostikum |
FR2662539B1 (fr) * | 1990-05-23 | 1994-09-30 | Centre Nat Rech Scient | Procede d'obtention de supports magnetiques finement divises par modification controlee de la surface de particules precurseurs magnetiques chargees et produits obtenus. |
FR2666443A1 (fr) * | 1990-08-31 | 1992-03-06 | Commissariat Energie Atomique | Materiau a base de polymere conducteur electronique comprenant des particules magnetiques et son procede de fabrication. |
US5294369A (en) * | 1990-12-05 | 1994-03-15 | Akzo N.V. | Ligand gold bonding |
US5610274A (en) * | 1991-11-20 | 1997-03-11 | Cpg, Inc. | Production and use of magnetic porous inorganic materials |
US5817292A (en) * | 1992-10-14 | 1998-10-06 | Nycomed Imaging As | MR imaging compositions and methods |
US5514340A (en) * | 1994-01-24 | 1996-05-07 | Magnetix Biotechnology, Inc. | Device for separating magnetically labelled cells |
-
1995
- 1995-06-29 FR FR9507865A patent/FR2736197B1/fr not_active Expired - Lifetime
-
1996
- 1996-06-20 EP EP96922967A patent/EP0847528A1/de not_active Withdrawn
- 1996-06-20 WO PCT/FR1996/000964 patent/WO1997001760A1/fr not_active Application Discontinuation
- 1996-06-20 US US08/981,239 patent/US6150181A/en not_active Expired - Lifetime
Non-Patent Citations (1)
Title |
---|
See references of WO9701760A1 * |
Also Published As
Publication number | Publication date |
---|---|
US6150181A (en) | 2000-11-21 |
WO1997001760A1 (fr) | 1997-01-16 |
FR2736197B1 (fr) | 1997-09-12 |
FR2736197A1 (fr) | 1997-01-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0847528A1 (de) | Magnetische nanopartikel gehoppelt an annexine und ihre verwendung | |
EP1957978B1 (de) | Magnetisch-immundiagnostisches verfahren zur demonstration von antikörper/antigen-komplexen, vor allem von blutgruppen | |
US4332783A (en) | Process for immunologic determination tests | |
EP0064274B1 (de) | Verfahren zur Bestimmung von Antigen-Antikörper-Reaktionen und Reagens hierfür | |
CA2565114A1 (fr) | Utilisation de ferrofluides pour le phenotypage sanguin et applications derivees | |
EP0311492B1 (de) | Immuntestsatz und -verfahren für ganze Zellen | |
US7553676B2 (en) | Specific coupling reaction measuring method | |
CA1215919A (en) | Detection of malignant tumor cells | |
Klimov et al. | On the ability of high density lipoproteins to remove phospholipid peroxidation products from erythrocyte membranes | |
JP4536588B2 (ja) | 成人t細胞白血病の診断器具 | |
EP0193439B1 (de) | Reagenz zur Bestimmung durch Hämagglutination von Antikörpern gegen Bakterien-Toxine, Verfahren zu ihrer Herstellung und Verwendung | |
WO1990007118A2 (fr) | Anticorps polymerises, diriges contre des immunoglobulines - leur utilisation dans des tests de diagnostic | |
US5017472A (en) | Microflotation devices used for immunoassays and cell/molecular fractionation | |
JPH10508095A (ja) | 体組織全鉄分貯蔵量測定方法 | |
FR2460482A1 (fr) | Composition et procede de titrage de l'erythropoietine humaine | |
D'Alesandro et al. | Trypanosoma lewisi: avidity and adsorbability of ablastin, the rat antibody inhibiting parasite reproduction | |
EP1573336B1 (de) | Verfahren zur detektion von prpsc unter verwendung von gruppe ii aminoglykosid antibiotika | |
JPS6232363A (ja) | 抗核抗体の検出方法及び装置 | |
EP0713094A1 (de) | Heterogener Immunoassay mittels präzipitierbarer Festphase | |
EP0598014B1 (de) | Verwendung von Atelokollagen als Festträger für die Fixierung eines spezifischen Fängers | |
WO2010128232A2 (fr) | Méthode de diagnostic des infections à propionibacterium acnes | |
JPH10505423A (ja) | 細胞分離 | |
RU2196335C1 (ru) | Способ определения гетерогенных антигенов, сходных для микроорганизмов и органов человека и животного | |
SU1143411A1 (ru) | Способ диагностики хронического пиелонефрита | |
EP1364214A1 (de) | Reagenzien zum nachweis von antemortem transmissiblen spongiformen enzephalopathien |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19980126 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): DE GB |
|
17Q | First examination report despatched |
Effective date: 20030814 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20060308 |