EP0825874A1 - Composition de tyrosine et d'allergene polymerise - Google Patents

Composition de tyrosine et d'allergene polymerise

Info

Publication number
EP0825874A1
EP0825874A1 EP96914124A EP96914124A EP0825874A1 EP 0825874 A1 EP0825874 A1 EP 0825874A1 EP 96914124 A EP96914124 A EP 96914124A EP 96914124 A EP96914124 A EP 96914124A EP 0825874 A1 EP0825874 A1 EP 0825874A1
Authority
EP
European Patent Office
Prior art keywords
allergen
tyrosine
solution
polymerised
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96914124A
Other languages
German (de)
English (en)
Inventor
Alan Worland SmithKline Beecham Phar. WHEELER
Iain SmithKline Beecham Pharmaceuticals TAYLOR
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergy Therapeutics UK Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of EP0825874A1 publication Critical patent/EP0825874A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Definitions

  • the allergen may be derived from any allergy causing substance, such as a pollen (e.g. ragweed or birch pollen), food, insect venom, mould, animal fur, or house dust mite (D. farinae or D. pteronyssinus).
  • a pollen e.g. ragweed or birch pollen
  • food insect venom, mould, animal fur, or house dust mite
  • D. farinae or D. pteronyssinus derived from D. pteronyssinus.
  • allergen includes a mixture of allergens which may be from a single source or more than one source.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Composition pharmaceutique comportant de la tyrosine et un allergène polymérisé, préparée (a) par polymérisation d'un allergène, (b) par mélange d'une solution aqueuse dudit allergène avec une solution de tyrosine dans un acide aqueux fort, (c) par neutralisation du mélange de solutions, ce qui entraîne une co-précipitation de la tyrosine et de l'allergène polymérisé, et (d) par mélange éventuel du produit avec un excipient physiologiquement acceptable.
EP96914124A 1995-04-29 1996-04-25 Composition de tyrosine et d'allergene polymerise Withdrawn EP0825874A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9508785.4A GB9508785D0 (en) 1995-04-29 1995-04-29 Novel compositions
GB9508785 1995-04-29
PCT/EP1996/001733 WO1996034626A1 (fr) 1995-04-29 1996-04-25 Composition de tyrosine et d'allergene polymerise

Publications (1)

Publication Number Publication Date
EP0825874A1 true EP0825874A1 (fr) 1998-03-04

Family

ID=10773769

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96914124A Withdrawn EP0825874A1 (fr) 1995-04-29 1996-04-25 Composition de tyrosine et d'allergene polymerise

Country Status (20)

Country Link
EP (1) EP0825874A1 (fr)
JP (1) JPH11504338A (fr)
KR (1) KR19990008120A (fr)
CN (1) CN1132629C (fr)
AU (1) AU705873B2 (fr)
BG (1) BG63990B1 (fr)
BR (1) BR9608123A (fr)
CA (1) CA2217388A1 (fr)
CZ (1) CZ288401B6 (fr)
EA (1) EA199700271A1 (fr)
GB (1) GB9508785D0 (fr)
HK (1) HK1010834A1 (fr)
HU (1) HUP9802237A3 (fr)
NO (1) NO974893L (fr)
NZ (1) NZ308080A (fr)
PL (1) PL183484B1 (fr)
SK (1) SK281877B6 (fr)
TR (1) TR199701265T1 (fr)
WO (1) WO1996034626A1 (fr)
ZA (1) ZA963340B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9706957D0 (en) * 1997-04-05 1997-05-21 Smithkline Beecham Plc Formulation
GB9820525D0 (en) 1998-09-21 1998-11-11 Allergy Therapeutics Ltd Formulation
GB0000891D0 (en) 2000-01-14 2000-03-08 Allergy Therapeutics Ltd Formulation
GB201106802D0 (en) * 2011-04-21 2011-06-01 Allergy Therapeutics Ltd Process for preparing vaccine composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1377074A (en) * 1971-07-13 1974-12-11 Beecham Group Ltd Process for preparing injectable compositions
US4070455A (en) * 1974-02-16 1978-01-24 Beecham Group Limited Process for preparing injectable desensitizing compositions and products thereof in microparticle form
EP0058021A3 (fr) * 1981-02-06 1982-10-27 Beecham Group Plc Compositions pharmaceutiques
ES2013359A6 (es) * 1988-11-04 1990-05-01 Corporacion Biolog Farmaceutic Procedimiento para la fabricacion de alergenos inmunogenicos polimerizados.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9634626A1 *

Also Published As

Publication number Publication date
BR9608123A (pt) 1999-02-09
JPH11504338A (ja) 1999-04-20
SK146197A3 (en) 1998-05-06
BG102004A (en) 1998-11-30
HK1010834A1 (en) 1999-07-02
AU5761696A (en) 1996-11-21
EA199700271A1 (ru) 1998-04-30
CZ288401B6 (en) 2001-06-13
TR199701265T1 (xx) 1998-02-21
CN1183046A (zh) 1998-05-27
CN1132629C (zh) 2003-12-31
PL323104A1 (en) 1998-03-16
AU705873B2 (en) 1999-06-03
NO974893D0 (no) 1997-10-23
BG63990B1 (bg) 2003-09-30
KR19990008120A (ko) 1999-01-25
CA2217388A1 (fr) 1996-11-07
WO1996034626A1 (fr) 1996-11-07
PL183484B1 (pl) 2002-06-28
NO974893L (no) 1997-10-23
NZ308080A (en) 1999-05-28
HUP9802237A3 (en) 2000-06-28
GB9508785D0 (en) 1995-06-21
SK281877B6 (sk) 2001-08-06
CZ342997A3 (cs) 1998-03-18
ZA963340B (en) 1997-03-27
HUP9802237A2 (hu) 1999-02-01

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