EP0590105A1 - Ampoule autocassable. - Google Patents
Ampoule autocassable.Info
- Publication number
- EP0590105A1 EP0590105A1 EP93902341A EP93902341A EP0590105A1 EP 0590105 A1 EP0590105 A1 EP 0590105A1 EP 93902341 A EP93902341 A EP 93902341A EP 93902341 A EP93902341 A EP 93902341A EP 0590105 A1 EP0590105 A1 EP 0590105A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- bulb
- line
- extension
- axis
- sleeve
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/065—Rigid ampoules, e.g. glass ampoules
Definitions
- the present invention relates to a self-breaking bulb allowing easy flow of the product contained in the bulb.
- self-breaking bulbs are glass bulbs comprising, in the vicinity of at least one of their ends, in a neck area of diameter smaller than that of the body of the bulb, a pre-baking line so that the user can break the bulb without a file, by exerting with the fingers a simple lateral pressure on the bulb, on both sides of the pre-baking line.
- This pre-crushing line can be obtained by numerous methods such as filing, localized deposition of an enamel on the glass, localized heating or the like.
- the diameter at the pre-crushing line is limited by the possibility of manually breaking the bulb. In practice, this diameter cannot exceed approximately 8 mm. Under these conditions, one cannot obtain an opening allowing the free flow of the product as with a bottle. Consequently, the flow of the fluid contained in the ampoules is often difficult and the user is led to vigorously shake the ampoule to empty it.
- the problem of the flow of the product can be solved by fitting a plastic sleeve which forms, after the ampoule neck area, at the level of the pre-baking line. breaking and eliminating the broken end, an extension of the neck area projecting beyond the broken edge of the bulb.
- the present invention therefore relates to a self-breaking bulb whose body contains a fluid product and which is provided, in the vicinity of one of its ends, with a neck of revolution zone around an axis, a pre-baking line being formed on said neck area, characterized in that said neck area is covered, at the level of the pre-crushing line, with a sleeve of plastic material projecting, over at least one angular sector, beyond the line of pre-crushing on the side opposite the body by forming an extension, the projection of which on the axis has a length at least equal to 20% of the diameter of the defined orifice, after breaking the bulb along the pre-crushing line, by the edge of the part of the neck remaining adjacent to the body, the plane tangent to the surface forming said extension in the vicinity of the pre-crushing line forming with the axis of the neck zone an angle alpha less than 60 °.
- the alpha angle is preferably between 40 and 50 °.
- the plastic sleeve is preferably made of heat-shrinkable plastic material.
- the heat-shrinkable plastic material may, in known manner, consist of a polyolefin, a fluorinated plastic such as polyvinylidene fluoride or tetrafluoroethylene, elastomers such as fluoelastomers and silicones having shrinkage temperatures of the order of 90 to 100 ° C.
- the heat-shrinkable sleeve preferably has a thickness of between 0.04 and 0.5 mm.
- the extension is preferably made all around the axis of the neck area over an angular sector of 360 °.
- the free edge 5 of the extension is advantageously substantially in a plane perpendicular to the axis of the neck.
- the plastic sleeve can have any length on the side opposite the extension: it can, in particular, cover most of the bulb and serve as a label.
- the invention also has the advantage of preventing the formation of shards of glass when the end of the bulb is broken.
- the presence of the extension prevents the user from injuring himself with the edge of the neck after breaking.
- FIG. 2 represents the same bulb after breaking.
- the bulb shown in Figure 1 is a glass bulb type "bottle", which is designated as a whole by the reference 1.
- the bulb 1 is of revolution about a longitudinal axis X-X; it comprises a cylindrical body 3, in which is contained a
- the body 3 is closed, at one of its ends along the axis XX, by a concave bottom 2; the other end is formed by a neck area 4 of diameter smaller than that of the body 3 and connected to the latter by a shoulder 5.
- the neck zone 4 is constituted by a cylindrical part 6 connected to an annular zone of smaller diameter than the cylindrical part 6, on which a pre-pressing line 7 has been provided, for example by filing.
- the annular zone is attached to a bulb 8, the tip 9 of which has been closed by welding after filling of the body 3 of the bulb.
- a sleeve 10 made of heat-shrinkable plastic surrounds the cylindrical part 6 of the neck, the annular zone on which the pre-pressing line 7 is engraved and part of the bulb 8.
- This plastic sleeve was placed on the neck zone 4 by placing on the shoulder 5 a section of cylindrical tube formed of a sheet of heat-shrinkable polyester having a thickness of 0.04 mm, and by heating it to 90 ° C so as to form a sleeve 10, which fits tightly, without glue, on the neck area 4.
- the outside diameter of the neck area 4 at the level of the pre-pressing line 7 is 6 mm and the distance d (measured in projection on the axis XX) between the pre-pressing line 7 and the edge of the sleeve 10 on the bulb 8 is about 2 mm.
- the thickness £ of the glass constituting the bulb is approximately 0.7 mm.
- the viscosity of product P is 45 centipoise and its surface tension is 30 Dyn / cm.
- the product is first in contact with the glass wall of the cylindrical part 6 of the neck area 4, then with the plastic of the internal wall of the extension 10b of the sleeve. In passing, it crosses a step 11 corresponding to the thickness of the glass at the level of the pre-pressing line 7. It is found that the product P flows easily, without it being necessary to shake the bulb 1.
Landscapes
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
- Disintegrating Or Milling (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9201347A FR2687066A1 (fr) | 1992-02-06 | 1992-02-06 | Ampoule autocassable. |
FR9201347 | 1992-02-06 | ||
PCT/FR1992/001196 WO1993015707A1 (fr) | 1992-02-06 | 1992-12-17 | Ampoule autocassable |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0590105A1 true EP0590105A1 (fr) | 1994-04-06 |
EP0590105B1 EP0590105B1 (fr) | 1996-03-20 |
Family
ID=9426403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP93902341A Expired - Lifetime EP0590105B1 (fr) | 1992-02-06 | 1992-12-17 | Ampoule autocassable |
Country Status (7)
Country | Link |
---|---|
US (1) | US5379898A (fr) |
EP (1) | EP0590105B1 (fr) |
JP (1) | JP3433294B2 (fr) |
DE (1) | DE69209292T2 (fr) |
ES (1) | ES2085141T3 (fr) |
FR (1) | FR2687066A1 (fr) |
WO (1) | WO1993015707A1 (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19843561A1 (de) * | 1998-09-23 | 2000-03-30 | Weimar Pharma Gmbh | Ampulle |
US7100600B2 (en) * | 2001-03-20 | 2006-09-05 | Aerogen, Inc. | Fluid filled ampoules and methods for their use in aerosolizers |
EP1598059A1 (fr) | 2001-05-18 | 2005-11-23 | Chiron Corporation | Méthodes et formulations en doses unitaires pour l'administration d'aminoglycosides par inhalation |
DE60210402T2 (de) | 2001-05-18 | 2006-12-07 | Chiron Corp., Emeryville | System zur Abgabe einer Tobramycin-Formulierung |
DE10209990B4 (de) * | 2002-03-07 | 2007-02-08 | Rudolf Gantenbrink | Flasche und Verfahren zu deren Herstellung |
ES2223235B1 (es) * | 2002-08-19 | 2006-04-01 | Ana Elvira Jimenez Florez | Sistema de apertura, proteccion y dosificacion de ampollas que contienen producto liquido cosmetico-farmaceutico. |
US7490723B2 (en) * | 2004-06-23 | 2009-02-17 | Ricardo Levisman | Easy-to-open glass ampoule and device |
US20050111900A1 (en) * | 2004-11-30 | 2005-05-26 | Francesca Fazzolari | Ampoule and method of use |
US7581899B2 (en) * | 2004-11-30 | 2009-09-01 | James Alexander Corporation | Dispenser and process |
DE102005038619A1 (de) * | 2005-08-16 | 2007-02-22 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung mit einer Ampulle für die Bevorratung eines zu vernebelnden Medikaments |
DE202005014444U1 (de) * | 2005-09-13 | 2005-11-17 | Schreiner Group Gmbh & Co. Kg | Geschützter Behälter mit Sollbruchstelle |
US7976234B2 (en) | 2006-04-28 | 2011-07-12 | James Alexander Corporation | Multi-chambered dispenser and process |
DE102007056462B4 (de) * | 2007-11-23 | 2011-10-27 | Pari Pharma Gmbh | Einwegampulle für eine Vorrichtung zur Erzeugung von Aerosolen |
US8910830B2 (en) | 2007-12-18 | 2014-12-16 | James Alexander Corporation | Container assembly |
US8631941B2 (en) * | 2010-04-22 | 2014-01-21 | James Alexander Corporation | Ampoule dispenser assembly and process |
US20120267335A1 (en) * | 2010-10-19 | 2012-10-25 | Chris Cindrich | Ampoule with protective sleeve for contamination prevention |
US8827093B1 (en) * | 2010-12-28 | 2014-09-09 | Maria A. Mendez | Bottle nipple device |
ES2566178T3 (es) * | 2011-04-06 | 2016-04-11 | Otsuka Pharmaceutical Factory, Inc. | Ampolla de plástico |
CA2873598A1 (fr) | 2012-05-21 | 2013-11-28 | Sanofi | Emballage unitaire pour un recipient rempli d'un produit pharmaceutique liquide |
CA176850S (en) * | 2017-06-28 | 2019-04-16 | Ami Cosmetic Co Ltd | Ampoule cap |
CN108785078A (zh) * | 2018-08-13 | 2018-11-13 | 吴德浩 | 一种透明pp安瓶 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB572176A (en) * | 1943-09-11 | 1945-09-26 | Leonard Charles Casselle | Improvements in and relating to ampoules and like vessels |
FR941772A (fr) * | 1947-02-17 | 1949-01-20 | Entonnoir verseur | |
US4506793A (en) * | 1983-08-01 | 1985-03-26 | Cordis Corporation | Breakable vial |
US4826025A (en) * | 1986-11-21 | 1989-05-02 | Toppan Printing Co., Ltd. & Mect Corp. | Ampoule package |
DE3808308A1 (de) * | 1988-03-12 | 1989-09-21 | Merck Patent Gmbh | Oeffnungshilfe fuer ampullen |
-
1992
- 1992-02-06 FR FR9201347A patent/FR2687066A1/fr active Granted
- 1992-12-17 EP EP93902341A patent/EP0590105B1/fr not_active Expired - Lifetime
- 1992-12-17 US US08/117,100 patent/US5379898A/en not_active Expired - Lifetime
- 1992-12-17 DE DE69209292T patent/DE69209292T2/de not_active Expired - Fee Related
- 1992-12-17 ES ES93902341T patent/ES2085141T3/es not_active Expired - Lifetime
- 1992-12-17 WO PCT/FR1992/001196 patent/WO1993015707A1/fr active IP Right Grant
- 1992-12-17 JP JP51381893A patent/JP3433294B2/ja not_active Expired - Fee Related
Non-Patent Citations (1)
Title |
---|
See references of WO9315707A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0590105B1 (fr) | 1996-03-20 |
ES2085141T3 (es) | 1996-05-16 |
DE69209292T2 (de) | 1996-11-21 |
FR2687066B1 (fr) | 1997-02-14 |
JP3433294B2 (ja) | 2003-08-04 |
FR2687066A1 (fr) | 1993-08-13 |
WO1993015707A1 (fr) | 1993-08-19 |
JPH06506626A (ja) | 1994-07-28 |
DE69209292D1 (de) | 1996-04-25 |
US5379898A (en) | 1995-01-10 |
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