EP0585369B1 - Simultaneous multiple assays - Google Patents

Simultaneous multiple assays Download PDF

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Publication number
EP0585369B1
EP0585369B1 EP92912635A EP92912635A EP0585369B1 EP 0585369 B1 EP0585369 B1 EP 0585369B1 EP 92912635 A EP92912635 A EP 92912635A EP 92912635 A EP92912635 A EP 92912635A EP 0585369 B1 EP0585369 B1 EP 0585369B1
Authority
EP
European Patent Office
Prior art keywords
particle
unique
particles
light
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP92912635A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0585369A1 (en
EP0585369A4 (en
Inventor
W. Peter Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sienna Biotech Inc
Original Assignee
Sienna Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sienna Biotech Inc filed Critical Sienna Biotech Inc
Publication of EP0585369A1 publication Critical patent/EP0585369A1/en
Publication of EP0585369A4 publication Critical patent/EP0585369A4/en
Application granted granted Critical
Publication of EP0585369B1 publication Critical patent/EP0585369B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N2015/0092—Monitoring flocculation or agglomeration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4704—Angular selective
    • G01N2021/4707—Forward scatter; Low angle scatter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Luminescent Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Optical Measuring Cells (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Hard Magnetic Materials (AREA)
  • Complex Calculations (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Farming Of Fish And Shellfish (AREA)
EP92912635A 1991-05-20 1992-05-19 Simultaneous multiple assays Expired - Lifetime EP0585369B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US70230291A 1991-05-20 1991-05-20
US702302 1991-05-20
US883574 1992-05-15
US07/883,574 US5286452A (en) 1991-05-20 1992-05-15 Simultaneous multiple assays
PCT/US1992/004155 WO1992021024A1 (en) 1991-05-20 1992-05-19 Simultaneous multiple assays

Publications (3)

Publication Number Publication Date
EP0585369A1 EP0585369A1 (en) 1994-03-09
EP0585369A4 EP0585369A4 (en) 1996-07-10
EP0585369B1 true EP0585369B1 (en) 1998-07-29

Family

ID=27106944

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92912635A Expired - Lifetime EP0585369B1 (en) 1991-05-20 1992-05-19 Simultaneous multiple assays

Country Status (16)

Country Link
US (2) US5286452A (fi)
EP (1) EP0585369B1 (fi)
JP (1) JPH06507972A (fi)
KR (1) KR100215348B1 (fi)
AT (1) ATE169116T1 (fi)
AU (1) AU656399B2 (fi)
CA (1) CA2103455A1 (fi)
DE (1) DE69226433T2 (fi)
DK (1) DK0585369T3 (fi)
ES (1) ES2120448T3 (fi)
FI (1) FI935128A0 (fi)
IE (1) IE921598A1 (fi)
NO (1) NO934205D0 (fi)
RU (1) RU2111488C1 (fi)
TW (1) TW197940B (fi)
WO (1) WO1992021024A1 (fi)

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US5547833A (en) * 1994-01-04 1996-08-20 Intracel Corporation Radial flow assay, delivering member, test kit, and methods
US5485270A (en) * 1994-07-25 1996-01-16 General Signal Corporation Dynamic light scattering microvolume cell assembly for continuous flow dialysis
US6159748A (en) * 1995-03-13 2000-12-12 Affinitech, Ltd Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry
US6951716B2 (en) * 1995-03-13 2005-10-04 Mark Hechinger Anti-platelet immunoglobulin bead positive control
US20030008410A1 (en) * 1995-03-13 2003-01-09 Hechinger Mark K. Immunoassay apparatus, kit and methods
AU3094195A (en) * 1995-07-10 1997-02-10 Donald L. Kramer Light transmittance type analytical system, variable transmittance optical component, and test device
US5736330A (en) * 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
EP0852004B1 (en) 1995-10-11 2011-01-19 Luminex Corporation Multiplexed analysis of clinical specimens
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US5817519A (en) * 1995-12-28 1998-10-06 Bayer Corporation Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US6025201A (en) * 1995-12-28 2000-02-15 Bayer Corporation Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US5851777A (en) * 1996-02-05 1998-12-22 Dade Behring Inc. Homogeneous sol-sol assay
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IL126544A (en) 1996-04-25 2004-08-31 Genicon Sciences Inc Test for component detection using detectable particles in diffused light
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
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AU2322099A (en) * 1998-01-16 1999-08-02 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
ITTO980473A1 (it) * 1998-06-02 1999-12-02 Sorin Diagnostics S R L Nuovo procedimento per la rivelazione di anticorpi e/o isotipi di anticorpi specifici per almeno due differenti fasi di un'infezione
US6315952B1 (en) 1998-10-05 2001-11-13 The University Of New Mexico Plug flow cytometry for high throughput screening and drug discovery
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US6480276B1 (en) 1999-07-13 2002-11-12 Clemson University Enhanced photon-migration methods for particle sizing in concentrated suspensions
US6890487B1 (en) * 1999-09-30 2005-05-10 Science & Technology Corporation ©UNM Flow cytometry for high throughput screening
US7416903B2 (en) * 1999-09-30 2008-08-26 Stc.Unm Wavy interface mixer
US6392327B1 (en) 2000-03-29 2002-05-21 James L. Sackrison Sonic transducer and feedback control method thereof
US20020028434A1 (en) * 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
JP2005507489A (ja) * 2001-02-23 2005-03-17 ジェニコン サイエンスィズ コーポレーション 検体分析において拡張ダイナミックレンジを提供する方法
DE10122806A1 (de) * 2001-05-10 2002-11-14 Holger Kiesewetter Verfahren zum Nachweis von Blutzell-Antigenen und gegen diese gerichtete Antikörper
WO2004010099A2 (en) * 2001-05-16 2004-01-29 Burstein Technologies, Inc. Variable sampling for rendering pixelization of analysis results in optical bio-disc assembly
EP2309253A2 (en) * 2001-09-05 2011-04-13 Life Technologies Corporation Apparatus for reading signals generated from resonance light scattered particle labels
US20030109067A1 (en) 2001-12-06 2003-06-12 Immunetech, Inc. Homogeneous immunoassays for multiple allergens
FR2834796B1 (fr) * 2002-01-11 2006-01-06 Biomedical Diagnostics Sa Procede d'obtention d'un systeme d'etalonnage unique applique aux dosages multiparametriques d'echantillons biologiques, reactif immunologique prepare a cette fin et procede de dosage
DE60308259T2 (de) * 2002-05-22 2007-04-05 Sysmex Corp. Immunologische Verfahren, Vorrichtungen und Reagenzien
US7560239B2 (en) * 2002-06-04 2009-07-14 Lin-Zhi International Inc. Homogeneous enzyme immunoassay for simultaneous detection of multiple analytes
US7016791B2 (en) * 2002-10-02 2006-03-21 Airadvice, Inc. Particle sizing refinement system
AU2003279801A1 (en) * 2002-10-02 2004-04-23 Airadvice, Inc. Method and apparatus for particle sizing
CN100357737C (zh) * 2002-11-12 2007-12-26 松下电器产业株式会社 特异结合反应测定方法、测定装置以及其中所用试剂盒
US7053783B2 (en) 2002-12-18 2006-05-30 Biovigilant Systems, Inc. Pathogen detector system and method
WO2005029078A1 (en) * 2003-09-17 2005-03-31 Guava Technologies, Inc. Compositions and methods for analysis of target analytes
US20070054405A1 (en) * 2003-10-23 2007-03-08 Ortho-Clinical Diagnostics, Inc. Patient sample classification based upon low angle light scattering
US20050141843A1 (en) * 2003-12-31 2005-06-30 Invitrogen Corporation Waveguide comprising scattered light detectable particles
US7430046B2 (en) * 2004-07-30 2008-09-30 Biovigilant Systems, Inc. Pathogen and particle detector system and method
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US7851229B2 (en) * 2006-05-12 2010-12-14 Primus Corporation Two-phase optical assay with unitized container and double or single sensor systems
US7859664B2 (en) * 2007-09-13 2010-12-28 Brightwell Technologies Inc. Plurality of samples and method for selecting a target sample therefrom
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Also Published As

Publication number Publication date
US5369037A (en) 1994-11-29
FI935128A (fi) 1993-11-19
US5286452A (en) 1994-02-15
AU2142092A (en) 1992-12-30
EP0585369A1 (en) 1994-03-09
DE69226433T2 (de) 1998-12-03
IE921598A1 (en) 1992-12-02
DE69226433D1 (de) 1998-09-03
EP0585369A4 (en) 1996-07-10
ES2120448T3 (es) 1998-11-01
ATE169116T1 (de) 1998-08-15
CA2103455A1 (en) 1992-11-21
AU656399B2 (en) 1995-02-02
TW197940B (fi) 1993-01-11
FI935128A0 (fi) 1993-11-19
WO1992021024A1 (en) 1992-11-26
RU2111488C1 (ru) 1998-05-20
DK0585369T3 (da) 1999-04-26
JPH06507972A (ja) 1994-09-08
KR100215348B1 (ko) 1999-08-16
NO934205L (no) 1993-11-19
NO934205D0 (no) 1993-11-19

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