EG20309A - Process for preparing of therapeutic agent and its use as anti-inflammatory and anti-pyretic - Google Patents

Process for preparing of therapeutic agent and its use as anti-inflammatory and anti-pyretic

Info

Publication number
EG20309A
EG20309A EG24792A EG24792A EG20309A EG 20309 A EG20309 A EG 20309A EG 24792 A EG24792 A EG 24792A EG 24792 A EG24792 A EG 24792A EG 20309 A EG20309 A EG 20309A
Authority
EG
Egypt
Prior art keywords
isobutylphenyl
pyretic
inflammatory
preparing
sodium
Prior art date
Application number
EG24792A
Other languages
English (en)
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26298899&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EG20309(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB919110342A external-priority patent/GB9110342D0/en
Priority claimed from GB919112058A external-priority patent/GB9112058D0/en
Application filed by Boots Co Plc filed Critical Boots Co Plc
Application granted granted Critical
Publication of EG20309A publication Critical patent/EG20309A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
EG24792A 1991-05-13 1992-05-12 Process for preparing of therapeutic agent and its use as anti-inflammatory and anti-pyretic EG20309A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919110342A GB9110342D0 (en) 1991-05-13 1991-05-13 Therapeutic agent
GB919112058A GB9112058D0 (en) 1991-06-05 1991-06-05 Therapeutic agent

Publications (1)

Publication Number Publication Date
EG20309A true EG20309A (en) 1998-10-31

Family

ID=26298899

Family Applications (1)

Application Number Title Priority Date Filing Date
EG24792A EG20309A (en) 1991-05-13 1992-05-12 Process for preparing of therapeutic agent and its use as anti-inflammatory and anti-pyretic

Country Status (32)

Country Link
US (3) US6525214B1 (de)
EP (1) EP0584108B1 (de)
JP (1) JP3326174B2 (de)
KR (1) KR100198044B1 (de)
CN (1) CN1068305C (de)
AT (1) ATE195417T1 (de)
AU (1) AU658415B2 (de)
BG (1) BG61676B1 (de)
CA (1) CA2102530C (de)
CZ (1) CZ281717B6 (de)
DE (1) DE69231359T2 (de)
DK (1) DK0584108T3 (de)
EG (1) EG20309A (de)
ES (1) ES2148175T3 (de)
FI (1) FI109994B (de)
GE (1) GEP20002013B (de)
GR (1) GR3034780T3 (de)
HU (1) HU219242B (de)
IE (1) IE921393A1 (de)
IL (1) IL101818A (de)
MX (1) MX9202215A (de)
MY (1) MY110267A (de)
NO (2) NO304678B1 (de)
NZ (1) NZ242640A (de)
PT (1) PT100476B (de)
RO (1) RO118371B1 (de)
RU (1) RU2145219C1 (de)
SK (1) SK279279B6 (de)
TW (1) TW304940B (de)
UA (1) UA34430C2 (de)
WO (1) WO1992020334A1 (de)
YU (1) YU48928B (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69231359T2 (de) * 1991-05-13 2001-02-08 The Boots Co., Plc Ibuprofen-salz enthaltende pharmazeutische zusammensetzung
US5248813A (en) * 1992-10-14 1993-09-28 Ethyl Corporation Enantiomeric resolution
US5260482A (en) 1992-10-14 1993-11-09 Ethyl Corporation Enantiomeric resolution
GB9224021D0 (en) * 1992-11-16 1993-01-06 Boots Co Plc Effervescent compositions
DE59209706D1 (de) * 1992-12-01 1999-07-08 Spirig Ag S(+)-Ibuprofen enthaltende Arzneimittel
WO1994012460A1 (en) * 1992-12-02 1994-06-09 The Boots Company Plc Process for preparing substantially pure enantiomers of phenylpropionic acids
SI9300470A (en) * 1993-09-10 1995-04-30 Lek Tovarna Farmacevtskih Inclusion complexes of optically active and racemic ibuproxan with cyclodextrin derivates,process for their preparation,pharmaceutical preparations comprising the same and their use
EP0667149A1 (de) * 1994-02-14 1995-08-16 E-PHARMA TRENTO S.p.A. Ibuprofen enthaltende Brausemischung
IT1270239B (it) * 1994-06-17 1997-04-29 Zambon Spa Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
GB9603699D0 (en) * 1996-02-21 1996-04-17 Boots Co Plc Therapeutic composition
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
DE19814256A1 (de) * 1998-03-31 1999-10-07 Asta Medica Ag Feste, schnellzerfallende Cetirizin-Formulierungen
US20050063998A1 (en) * 1999-10-26 2005-03-24 Francois Marc Karel Jozef Oral solution containing galantamine and a sweetening agent
FR2800276B1 (fr) * 1999-10-27 2004-08-20 Palbian Snc Composition et medicament, notamment anti-inflammatoire, constitue de ladite composition
NZ508292A (en) * 1999-11-24 2002-08-28 Mcneil Ppc Inc Treatment of migraine symptoms with ibuprofen and salts thereof
CN1215837C (zh) * 2000-08-25 2005-08-24 兴和株式会社 布洛芬胶囊填充液和胶囊制剂
JP2002069030A (ja) * 2000-08-30 2002-03-08 Kyowa Hakko Kogyo Co Ltd ナトリウム2−{4−[(2−オキソシクロペンチル)メチル]フェニル}プロピオネート2水和物の製造法
GB0028575D0 (en) * 2000-11-23 2001-01-10 Elan Corp Plc Oral pharmaceutical compositions containing cyclodextrins
US6440983B1 (en) * 2000-12-21 2002-08-27 Mary Theresa Frank-Kollman Compositions and methods for relieving headache symptoms in aspirin-sensitive headache sufferers
WO2002083105A2 (en) * 2001-04-10 2002-10-24 Zagros Pharma Inc. Composition for enhanced absorption of nsaids
JP2003026634A (ja) * 2001-07-17 2003-01-29 Mercian Corp プラバスタチンナトリウム塩の製造方法
JP2005506333A (ja) * 2001-10-04 2005-03-03 マクロケム コーポレイション イブプロフェン塩乳化剤およびこれを含有するクリーム製剤
US20030124174A1 (en) * 2001-10-25 2003-07-03 Endo Pharmaceuticals, Inc Method for treating non-neuropathic pain
ATE424187T1 (de) * 2002-07-15 2009-03-15 Alcon Inc Bioerodierbare folie zur abgabe eines ophthalmischen arzneimittels
ES2295647T3 (es) * 2002-07-15 2008-04-16 Alcon, Inc. Composiciones de implante farmaceuticas lipofilas, no polimeras, para uso intraocular.
AU2003280960A1 (en) * 2002-07-15 2004-02-02 Alcon, Inc. Pharmaceutical compositions for otic use
US7863287B2 (en) * 2002-12-18 2011-01-04 Wyeth Llc Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines
US20040228804A1 (en) * 2003-05-16 2004-11-18 Jones Alonzo H. Nasal administration of xylitol to a non-human mammal
CZ295151B6 (cs) * 2004-02-20 2005-06-15 I. Q. A., A. S. Stabilní, chuťově přijatelné sirupy obsahující ibuprofen a způsob jejich přípravy
GB2411833A (en) * 2004-03-08 2005-09-14 Skin Salveation Ltd Composition for use in the treatment of dry skin conditions
MXPA06014185A (es) * 2004-06-07 2007-04-16 Strides Arcolab Ltd Composicion farmaceutica que contiene una solucion estable y clara de medicamento anti-inflmatorio en capsulas de gelatina blanda, y proceso para producirlo.
WO2005121061A1 (en) * 2004-06-07 2005-12-22 Strides Research And Specialty Chemicals Limited Novel process for producing ibuprofen sodium dihydrate
EP1804772B1 (de) * 2004-08-12 2011-10-05 Reckitt Benckiser Healthcare (UK) Limited Durch schmelzextrusion hergestelltes granulat mit einem nichtsteroidalen antiinflammatorischen wirkstoff und einem zuckeralkohol
US20080020040A1 (en) * 2006-07-18 2008-01-24 Horizon Therapeutics, Inc. Unit dose form for administration of ibuprofen
WO2007012019A2 (en) * 2005-07-18 2007-01-25 Horizon Therapeutics, Inc. Medicaments containing famotidine and ibuprofen and administration of same
US8067451B2 (en) * 2006-07-18 2011-11-29 Horizon Pharma Usa, Inc. Methods and medicaments for administration of ibuprofen
US8067033B2 (en) * 2007-11-30 2011-11-29 Horizon Pharma Usa, Inc. Stable compositions of famotidine and ibuprofen
CL2007002425A1 (es) 2006-08-22 2008-06-27 Albermarle Corp Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica.
FI20080348A0 (fi) * 2008-02-15 2008-05-09 Atacama Labs Oy Uudenlainen farmaseuttinen formulaatio
US20100055180A1 (en) * 2007-10-10 2010-03-04 Mallinckrodt Baker, Inc. Directly Compressible Granular Microcrystalline Cellulose Based Excipient, Manufacturing Process and Use Thereof
AU2008311289A1 (en) * 2007-10-10 2009-04-16 Avantor Performance Materials, Inc. Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof
EP2323976A4 (de) * 2008-08-14 2014-07-02 Shasun Chemicals And Drugs Ltd Arylalkylcarboxylsäuresalze, verfahren zu ihrer herstellung und dosierungsformen davon
EP3574921A1 (de) 2008-09-10 2019-12-04 BioChemics, Inc. Ibuprofen zur topischen verabreichung
BRPI0914192A2 (pt) 2008-09-22 2015-11-03 Biochemics Inc distribuição transdérmica de fármaco usando um osmólito e agente vasoativo
EP2351729B1 (de) * 2008-10-29 2014-01-22 Mitsubishi Gas Chemical Company, Inc. Verfahren zur herstellung von optisch aktiver organischer carboxylsäure
AU2014200704C1 (en) * 2009-06-22 2018-12-06 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
NZ620828A (en) * 2009-06-22 2014-08-29 Wyeth Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
AU2015264861C1 (en) * 2009-06-22 2017-11-16 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
PE20130245A1 (es) * 2009-12-16 2013-03-08 Shasun Pharmaceuticals Ltd Composicion de hidrogel de dexibuprofeno transdermico
CN102557918B (zh) * 2011-11-28 2013-08-21 海南永田药物研究院有限公司 一种布洛芬钠化合物及其制法
WO2013154511A1 (en) * 2012-04-13 2013-10-17 Mahmut Bilgic Film tablet formulations comprising dexibuprofen
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
CN102992997A (zh) * 2012-11-20 2013-03-27 北京阜康仁生物制药科技有限公司 右布洛芬的新药用盐
CN104744236A (zh) * 2013-12-26 2015-07-01 鲁南贝特制药有限公司 一种右旋布洛芬的精制方法
EP2965746B1 (de) 2014-07-10 2019-03-13 Santa Farma Ilaç Sanayi A.S. Orale pharmazeutische Zusammensetzung mit Ibuprofen, Ibuprofennatriumdihydrat, Pseudoephedrinhydrochlorid und Chlorpheniraminmaleat
US10561627B2 (en) 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
US11007161B1 (en) 2014-12-31 2021-05-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films
US10596117B1 (en) 2014-12-31 2020-03-24 Eric Morrison Lipoleosomes as carriers for aromatic amide anesthetic compounds

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
JPS5826744B2 (ja) 1975-12-24 1983-06-04 ヒサミツセイヤク カブシキガイシヤ シンキナプロピオンサン エステルユウドウタイノセイゾウホウ
JPS53112837A (en) 1977-03-11 1978-10-02 Mitsui Toatsu Chem Inc Method of isolation of alpha-phenylpropionic acid compound
DE3270988D1 (en) 1981-07-20 1986-06-12 Upjohn Co Use of ibuprofen or flurbiprofen for the manufacture of a medicament for treating respiratory disorders
GB8528195D0 (en) 1985-11-15 1985-12-18 Boots Co Plc Therapeutic compositions
US4873231A (en) 1986-04-08 1989-10-10 Smith Walton J Decreasing the toxicity of an ibuprofen salt
DE3621036A1 (de) * 1986-06-24 1988-01-07 Merckle Gmbh Fluessige ibuprofen-zubereitungen
US4684666A (en) 1986-08-19 1987-08-04 Haas Pharmaceuticals, Inc. Stabilized liquid analgesic compositions
DE3639038C2 (de) * 1986-11-14 1997-02-06 Helmut Dr Lukas Verwendung von S-(+)-Ibuprofen zur schnellen Behandlung humaner Schmerzen
GB8701392D0 (en) 1987-01-22 1987-02-25 Boots Co Plc Therapeutic agents
IT1222013B (it) 1987-07-10 1990-08-31 Chimica Profarmaco Spa Ind Processo di risoluzione ottica di acido 2 (6 metossi 2 naftil) propionico
US4851444A (en) 1987-07-10 1989-07-25 Analgesic Associates Onset-hastened/enhanced analgesia
US4980375A (en) 1987-07-10 1990-12-25 Sterling Drug Inc. Onset-hastened/enhanced antipyretic response
US4859704A (en) 1987-10-15 1989-08-22 Oratech Pharmaceutical Development Corporation Water soluble ibuprofen compositions and methods of making them
US4861797A (en) 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
IT1217988B (it) 1988-01-28 1990-03-30 Ind Chimica Profarmaco Spa Procedimento per la risoluzione ottica di un pacemo
DE3814887C1 (de) 1988-05-02 1989-09-21 Medice Chem.-Pharm. Fabrik Puetter Gmbh & Co Kg, 5860 Iserlohn, De
US4831147A (en) 1988-07-05 1989-05-16 The Dow Chemical Company Resolution of enantiomers of herbicidal 2-(4-aryloxyphenoxy) propionates by chiral two-phase extraction
CH677606A5 (de) 1988-07-12 1991-06-14 Aesculapius Pharma Sa
DE3838431A1 (de) 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
DD300404A5 (de) 1989-05-16 1992-06-11 Puetter Medice Chem Pharm Pharmazeutische zubereitung
US5100918A (en) 1989-05-25 1992-03-31 Sterling Drug, Inc. Prevention or treatment of sunburn using the S(+) isomer of ibuprofen
US4946997A (en) 1989-06-07 1990-08-07 Merck & Co., Inc. Racemization of a carboxylic acid
DE3922441A1 (de) 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
GB8920693D0 (en) 1989-09-13 1989-10-25 Nicholas Kiwi Pty Ltd Non-effervescent ibuprofen compositions
US5200558A (en) 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
US4994604A (en) 1990-01-10 1991-02-19 Merck & Co., Inc. Formation and resolution of ibuprofen lysinate
US5015764A (en) * 1990-06-18 1991-05-14 Ethyl Corporation Preparation of optically active aliphatic carboxylic acids
US5164398A (en) 1991-04-01 1992-11-17 Merck & Co., Inc. Ibuprofen-antitussive combinations
DE69231359T2 (de) * 1991-05-13 2001-02-08 The Boots Co., Plc Ibuprofen-salz enthaltende pharmazeutische zusammensetzung
US5189208A (en) 1991-07-01 1993-02-23 Ethyl Corporation Ibuprofen resolution
US5302751A (en) 1992-01-21 1994-04-12 Ethyl Corporation Profen resolution
US5235101A (en) 1992-01-24 1993-08-10 Ethyl Corporation Preparation by flotation of optically active aliphatic carboxylic acids
US5235100A (en) 1992-01-24 1993-08-10 Ethyl Corporation Preparation of optically active aliphatic carboxylic acids
US5220053A (en) 1992-01-24 1993-06-15 Ethyl Corporation Preparation of optically active aliphatic carboxylic acids
US5235095A (en) 1992-01-24 1993-08-10 Ethyl Corporation Preparation of optically active aliphatic carboxylic acids
US5248213A (en) 1992-01-27 1993-09-28 Plastek Industries, Inc. Seal for roll-on dispenser
US5260482A (en) 1992-10-14 1993-11-09 Ethyl Corporation Enantiomeric resolution
US5256816A (en) 1992-10-14 1993-10-26 Ethyl Corporation Enantiomeric resolution
US5248813A (en) 1992-10-14 1993-09-28 Ethyl Corporation Enantiomeric resolution
US5278337A (en) 1992-10-14 1994-01-11 Ethyl Corporation Enantiomeric resolution of aryl-substituted aliphatic carboxylic acids

Also Published As

Publication number Publication date
US6242000B1 (en) 2001-06-05
ES2148175T3 (es) 2000-10-16
US6525214B1 (en) 2003-02-25
FI934964A0 (fi) 1993-11-10
FI934964L (fi) 1993-11-10
NO934102D0 (no) 1993-11-12
HUT67034A (en) 1995-01-30
HU219242B (en) 2001-03-28
KR100198044B1 (ko) 1999-06-15
NO982500D0 (no) 1998-06-02
EP0584108B1 (de) 2000-08-16
WO1992020334A1 (en) 1992-11-26
CZ240593A3 (en) 1994-03-16
MX9202215A (es) 1992-11-01
TW304940B (de) 1997-05-11
HU9303220D0 (en) 1994-03-28
GEP20002013B (en) 2000-04-10
UA34430C2 (uk) 2001-03-15
GR3034780T3 (en) 2001-02-28
EP0584108A1 (de) 1994-03-02
DK0584108T3 (da) 2000-10-09
IL101818A (en) 1999-08-17
DE69231359D1 (de) 2000-09-21
NO304678B1 (no) 1999-02-01
RU2145219C1 (ru) 2000-02-10
US5696165B1 (en) 2000-12-05
BG98214A (bg) 1994-07-29
BG61676B1 (bg) 1998-03-31
RO118371B1 (ro) 2003-05-30
YU50292A (sh) 1995-03-27
CN1068305C (zh) 2001-07-11
MY110267A (en) 1998-03-31
FI109994B (fi) 2002-11-15
NZ242640A (en) 1993-11-25
JP3326174B2 (ja) 2002-09-17
SK125993A3 (en) 1994-04-06
SK279279B6 (sk) 1998-09-09
PT100476A (pt) 1993-08-31
CA2102530A1 (en) 1992-11-14
PT100476B (pt) 1999-09-30
AU1671192A (en) 1992-12-30
CN1068734A (zh) 1993-02-10
IL101818A0 (en) 1992-12-30
ATE195417T1 (de) 2000-09-15
NO982500L (no) 1993-11-12
IE921393A1 (en) 1992-11-18
NO934102L (no) 1993-11-12
DE69231359T2 (de) 2001-02-08
CZ281717B6 (cs) 1996-12-11
NO305696B1 (no) 1999-07-12
YU48928B (sh) 2002-12-10
AU658415B2 (en) 1995-04-13
US5696165A (en) 1997-12-09
CA2102530C (en) 2003-07-29
JPH06507159A (ja) 1994-08-11

Similar Documents

Publication Publication Date Title
US5696165B1 (en) Composition of s(-) sodium ibuprofen
RU93058389A (ru) Фармацевтическая композиция, содержащая s(-)-2-(4-изобутилфенил)пропионат натрия, способ ее получения, применение композиции, способы получения натриевой соли энантиомера 2-(4-изобутилфенил)пропионовой кислоты, s(-)-2-(4-изобутилфенил)пропионата натрия дигидрат
RU95112575A (ru) Соль арилпропионовой кислоты, способ ее получения и фармацевтическая композиция
RU94042899A (ru) Способ достижения болеутоляющего эффекта, способ лечения и профилактики гипертермии у человека, болеутоляющая и жаропонижающая композиции, содержащие оптически чистый r (-) кетопрофен
EG17609A (en) Process for preparation of therapeutic agents from derivatives of propoimic acid.
IT1170214B (it) Composizione farmaceutica per la cura delle arteriopatie periferiche
IL90056A0 (en) Topical pharmaceutical compositions containing 4-quinoline carboxylic acid derivatives
DE2967356D1 (en) Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
AU1395583A (en) Use of oleanolic acid for ulcer treatment
AU1027592A (en) New salts of 2-(2,6-dichloroanilino)-phenylacetic acid, a process for their preparation and their use for pharmaceutical preparations to be applied locally
ES8300747A1 (es) Procedimiento para la preparacion de derivados de acido in- dolacetico
ZA824649B (en) New optically active dipeptides, process for their preparation and pharmaceutical products containing these compounds
JPS5455715A (en) Amino acid preparation
IT1270699B (it) Sali dell'acido s(+)-2-(4-isobutilfenil)propionico con mono-, di- e trialcanolammine
Janku et al. Kinetics of tropesin disposition in blood plasma after single and multiple oral administration to healthy volunteers.
IT1255236B (it) Composizione farmaceutica idrofila per uso topico