ES2148175T3 - Composicion farmaceutica que contiene una sal de ibuprofeno. - Google Patents

Composicion farmaceutica que contiene una sal de ibuprofeno.

Info

Publication number
ES2148175T3
ES2148175T3 ES92909270T ES92909270T ES2148175T3 ES 2148175 T3 ES2148175 T3 ES 2148175T3 ES 92909270 T ES92909270 T ES 92909270T ES 92909270 T ES92909270 T ES 92909270T ES 2148175 T3 ES2148175 T3 ES 2148175T3
Authority
ES
Spain
Prior art keywords
isobutylphenyl
salt
ibuprofen
pharmaceutical composition
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92909270T
Other languages
English (en)
Inventor
Bernard John Armitage
Paul Frederick Coe
John Francis Lampard
Alan Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26298899&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2148175(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB919110342A external-priority patent/GB9110342D0/en
Priority claimed from GB919112058A external-priority patent/GB9112058D0/en
Application filed by Boots Co PLC filed Critical Boots Co PLC
Application granted granted Critical
Publication of ES2148175T3 publication Critical patent/ES2148175T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE DESCRIBE EL USO DE 2-$-ISOBUTILFENIL)PROPIONATO DE S(-) SODIO (LA SAL DE SODIO DE S+)-IBUPROFENO) EN COMPOSICIONES FARMACEUTICAS PARA EL TRATAMIENTO DE INFLAMACION, DOLOR Y PIREXIA. LAS COMPOSICIONES PREFERIDAS COMPRENDEN DIHIDRATO DE 2-(4ISOBUTILFENIL)PROPIONATO DE S(-) SODIO. TAMBIEN SE DESCRIBEN PROCESOS PARA PREPARAR 2-(4-ISOBUTILFENIL)PROPIONATO DE S-(-)SODIO Y SU USO EN UN PROCESO PARA PREPARAR ACIDO S(+) 2-(4-ISOBUTILFENIL)PROPIONICO DE ALTA PUREZA ENANTIOMERICA.
ES92909270T 1991-05-13 1992-05-04 Composicion farmaceutica que contiene una sal de ibuprofeno. Expired - Lifetime ES2148175T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919110342A GB9110342D0 (en) 1991-05-13 1991-05-13 Therapeutic agent
GB919112058A GB9112058D0 (en) 1991-06-05 1991-06-05 Therapeutic agent

Publications (1)

Publication Number Publication Date
ES2148175T3 true ES2148175T3 (es) 2000-10-16

Family

ID=26298899

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92909270T Expired - Lifetime ES2148175T3 (es) 1991-05-13 1992-05-04 Composicion farmaceutica que contiene una sal de ibuprofeno.

Country Status (32)

Country Link
US (3) US6525214B1 (es)
EP (1) EP0584108B1 (es)
JP (1) JP3326174B2 (es)
KR (1) KR100198044B1 (es)
CN (1) CN1068305C (es)
AT (1) ATE195417T1 (es)
AU (1) AU658415B2 (es)
BG (1) BG61676B1 (es)
CA (1) CA2102530C (es)
CZ (1) CZ281717B6 (es)
DE (1) DE69231359T2 (es)
DK (1) DK0584108T3 (es)
EG (1) EG20309A (es)
ES (1) ES2148175T3 (es)
FI (1) FI109994B (es)
GE (1) GEP20002013B (es)
GR (1) GR3034780T3 (es)
HU (1) HU219242B (es)
IE (1) IE921393A1 (es)
IL (1) IL101818A (es)
MX (1) MX9202215A (es)
MY (1) MY110267A (es)
NO (2) NO304678B1 (es)
NZ (1) NZ242640A (es)
PT (1) PT100476B (es)
RO (1) RO118371B1 (es)
RU (1) RU2145219C1 (es)
SK (1) SK279279B6 (es)
TW (1) TW304940B (es)
UA (1) UA34430C2 (es)
WO (1) WO1992020334A1 (es)
YU (1) YU48928B (es)

Families Citing this family (59)

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SK279279B6 (sk) * 1991-05-13 1998-09-09 The Boots Company Plc S(-)-nátrium-2-(4-izobutylfenyl)propionát-dihydrát
US5260482A (en) * 1992-10-14 1993-11-09 Ethyl Corporation Enantiomeric resolution
US5248813A (en) * 1992-10-14 1993-09-28 Ethyl Corporation Enantiomeric resolution
GB9224021D0 (en) * 1992-11-16 1993-01-06 Boots Co Plc Effervescent compositions
DK0607467T3 (da) * 1992-12-01 1999-12-13 Spirig Ag Lægemidler, der indeholder S(+)-ibuprofen
AU672269B2 (en) * 1992-12-02 1996-09-26 Aesica Pharmaceuticals Ltd Process for preparing substantially pure enantiomers of phenylpropionic acids
SI9300470A (en) * 1993-09-10 1995-04-30 Lek Tovarna Farmacevtskih Inclusion complexes of optically active and racemic ibuproxan with cyclodextrin derivates,process for their preparation,pharmaceutical preparations comprising the same and their use
EP0667149A1 (en) * 1994-02-14 1995-08-16 E-PHARMA TRENTO S.p.A. Ibuprofen based effervescent composition
IT1270239B (it) * 1994-06-17 1997-04-29 Zambon Spa Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo
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GB9603699D0 (en) * 1996-02-21 1996-04-17 Boots Co Plc Therapeutic composition
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DE19814256A1 (de) * 1998-03-31 1999-10-07 Asta Medica Ag Feste, schnellzerfallende Cetirizin-Formulierungen
US20050063998A1 (en) * 1999-10-26 2005-03-24 Francois Marc Karel Jozef Oral solution containing galantamine and a sweetening agent
FR2800276B1 (fr) * 1999-10-27 2004-08-20 Palbian Snc Composition et medicament, notamment anti-inflammatoire, constitue de ladite composition
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US6440983B1 (en) * 2000-12-21 2002-08-27 Mary Theresa Frank-Kollman Compositions and methods for relieving headache symptoms in aspirin-sensitive headache sufferers
US20030008003A1 (en) * 2001-04-10 2003-01-09 Fahkreddin Jamali Compositions for enhanced absorption of NSAIDs
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RU2004113433A (ru) * 2001-10-04 2005-03-20 Макрокем Корпорейшн (Us) Эмульгаторы на основе солей ибупрофена и препаративные формы в виде крема, содержащие указанные вещества
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WO2010050499A1 (ja) * 2008-10-29 2010-05-06 三菱瓦斯化学株式会社 光学活性有機カルボン酸の製造方法
AU2015264861C1 (en) * 2009-06-22 2017-11-16 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
RU2715680C2 (ru) * 2009-06-22 2020-03-03 ВАЙЕТ ЭлЭлСи Таблетки ибупрофена натрия и способы изготовления фармацевтических композиций, включающих ибупрофен натрия
AU2014200704C1 (en) * 2009-06-22 2018-12-06 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
BR112012014558B8 (pt) * 2009-12-16 2021-05-25 Shasun Pharmaceuticals Ltd nova composição de hidrogel transdérmico de dexibuprofeno
CN102557918B (zh) * 2011-11-28 2013-08-21 海南永田药物研究院有限公司 一种布洛芬钠化合物及其制法
WO2013154511A1 (en) * 2012-04-13 2013-10-17 Mahmut Bilgic Film tablet formulations comprising dexibuprofen
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
CN102992997A (zh) * 2012-11-20 2013-03-27 北京阜康仁生物制药科技有限公司 右布洛芬的新药用盐
CN104744236A (zh) * 2013-12-26 2015-07-01 鲁南贝特制药有限公司 一种右旋布洛芬的精制方法
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Also Published As

Publication number Publication date
NO304678B1 (no) 1999-02-01
EP0584108A1 (en) 1994-03-02
FI109994B (fi) 2002-11-15
CA2102530A1 (en) 1992-11-14
HUT67034A (en) 1995-01-30
DE69231359T2 (de) 2001-02-08
HU9303220D0 (en) 1994-03-28
SK125993A3 (en) 1994-04-06
MY110267A (en) 1998-03-31
AU1671192A (en) 1992-12-30
YU50292A (sh) 1995-03-27
SK279279B6 (sk) 1998-09-09
AU658415B2 (en) 1995-04-13
CN1068305C (zh) 2001-07-11
US5696165A (en) 1997-12-09
PT100476B (pt) 1999-09-30
YU48928B (sh) 2002-12-10
WO1992020334A1 (en) 1992-11-26
RU2145219C1 (ru) 2000-02-10
DK0584108T3 (da) 2000-10-09
FI934964L (fi) 1993-11-10
EP0584108B1 (en) 2000-08-16
CZ281717B6 (cs) 1996-12-11
MX9202215A (es) 1992-11-01
IL101818A0 (en) 1992-12-30
NO934102D0 (no) 1993-11-12
CZ240593A3 (en) 1994-03-16
NO982500L (no) 1993-11-12
GR3034780T3 (en) 2001-02-28
NO305696B1 (no) 1999-07-12
BG98214A (bg) 1994-07-29
EG20309A (en) 1998-10-31
ATE195417T1 (de) 2000-09-15
HU219242B (en) 2001-03-28
CN1068734A (zh) 1993-02-10
NO982500D0 (no) 1998-06-02
JPH06507159A (ja) 1994-08-11
IL101818A (en) 1999-08-17
IE921393A1 (en) 1992-11-18
FI934964A0 (fi) 1993-11-10
KR100198044B1 (ko) 1999-06-15
BG61676B1 (bg) 1998-03-31
CA2102530C (en) 2003-07-29
UA34430C2 (uk) 2001-03-15
JP3326174B2 (ja) 2002-09-17
DE69231359D1 (de) 2000-09-21
NZ242640A (en) 1993-11-25
GEP20002013B (en) 2000-04-10
US5696165B1 (en) 2000-12-05
NO934102L (no) 1993-11-12
US6525214B1 (en) 2003-02-25
PT100476A (pt) 1993-08-31
TW304940B (es) 1997-05-11
RO118371B1 (ro) 2003-05-30
US6242000B1 (en) 2001-06-05

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