EG20219A - Method of preparation of deiwatives indole used in preparation of pharmaceutical composition and treatment of migraine - Google Patents

Method of preparation of deiwatives indole used in preparation of pharmaceutical composition and treatment of migraine

Info

Publication number
EG20219A
EG20219A EG75391A EG75391A EG20219A EG 20219 A EG20219 A EG 20219A EG 75391 A EG75391 A EG 75391A EG 75391 A EG75391 A EG 75391A EG 20219 A EG20219 A EG 20219A
Authority
EG
Egypt
Prior art keywords
preparation
deiwatives
migraine
treatment
pharmaceutical composition
Prior art date
Application number
EG75391A
Other languages
English (en)
Inventor
Joanne Craig
Derek Leslie Crookes
Stephen John Skittrall
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of EG20219A publication Critical patent/EG20219A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
EG75391A 1990-12-12 1991-12-11 Method of preparation of deiwatives indole used in preparation of pharmaceutical composition and treatment of migraine EG20219A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909026998A GB9026998D0 (en) 1990-12-12 1990-12-12 Medicaments

Publications (1)

Publication Number Publication Date
EG20219A true EG20219A (en) 1997-11-30

Family

ID=10686904

Family Applications (1)

Application Number Title Priority Date Filing Date
EG75391A EG20219A (en) 1990-12-12 1991-12-11 Method of preparation of deiwatives indole used in preparation of pharmaceutical composition and treatment of migraine

Country Status (36)

Country Link
US (2) US5554639A (is)
EP (1) EP0490689B1 (is)
JP (1) JP2994037B2 (is)
KR (1) KR100211479B1 (is)
CN (2) CN1030890C (is)
AP (1) AP230A (is)
AT (1) ATE119881T1 (is)
AU (1) AU650706B2 (is)
BE (1) BE1005085A3 (is)
CA (1) CA2098302C (is)
CH (1) CH684192A5 (is)
CY (1) CY2005A (is)
CZ (1) CZ281931B6 (is)
DE (1) DE69108200T2 (is)
DK (1) DK0490689T3 (is)
EG (1) EG20219A (is)
ES (1) ES2069836T3 (is)
FR (1) FR2670487B1 (is)
GB (2) GB9026998D0 (is)
GR (1) GR3015430T3 (is)
HK (1) HK82697A (is)
HU (1) HU211937A9 (is)
IE (1) IE62894B1 (is)
IL (1) IL100330A (is)
IS (1) IS1706B (is)
IT (1) IT1252868B (is)
MX (1) MX9102501A (is)
MY (1) MY109265A (is)
NL (1) NL9102071A (is)
NZ (1) NZ240942A (is)
PT (1) PT99757B (is)
RU (1) RU2108328C1 (is)
TW (2) TW205035B (is)
WO (1) WO1992010477A1 (is)
YU (1) YU48926B (is)
ZA (1) ZA919750B (is)

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US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
US6187790B1 (en) 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
US6426084B1 (en) * 2000-06-19 2002-07-30 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6132757A (en) 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
GB9926250D0 (en) * 1999-11-06 2000-01-12 Knoll Ag Chemical process
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US6610271B2 (en) * 2000-05-10 2003-08-26 University Of Kentucky Research Foundation System and method for intranasal administration of lorazepam
US6562838B2 (en) 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
US20030096748A1 (en) * 2001-06-04 2003-05-22 The Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
DK1435945T3 (da) * 2001-06-05 2008-12-01 Ronald Aung-Din Topisk migræne terapi
US8329734B2 (en) 2009-07-27 2012-12-11 Afgin Pharma Llc Topical therapy for migraine
US7041677B2 (en) * 2002-03-01 2006-05-09 R.T. Alamo Ventures I, Llc Use of monochloroflosequinan in the treatment of sexual dysfunction
US7208628B2 (en) * 2002-05-13 2007-04-24 Kansas State University Research Foundation Compositions and methods for the treatment of hepatitis C virus infection
US7074893B2 (en) * 2002-06-03 2006-07-11 Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
CA2509023C (en) * 2002-12-26 2011-05-24 Pozen Inc. Multilayer dosage forms containing nsaids and triptans
US20080213363A1 (en) * 2003-01-23 2008-09-04 Singh Nikhilesh N Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa
WO2004076403A1 (en) * 2003-02-24 2004-09-10 Transform Pharmaceuticals, Inc. Sumatriptan crystalline forms, pharmaceutical compositions and methods
WO2004112723A2 (en) * 2003-06-20 2004-12-29 Ronald Aung-Din Tropical therapy for the treatment of migraines, muscle sprains, muscle spasm, spasticity and related conditions
US20050089558A1 (en) * 2003-10-28 2005-04-28 Alamo Pharmaceuticals, Llc Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
WO2005119607A2 (en) * 2004-06-03 2005-12-15 Tyfone, Inc. System and method for securing financial transactions
CA2569964A1 (en) * 2004-06-10 2005-12-29 Duramed Pharmaceuticals, Inc. Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
AU2006249577A1 (en) 2005-05-20 2006-11-30 Janssen Pharmaceutica N.V. Process for preparation of sulfamide derivatives
US20070166336A1 (en) * 2005-12-13 2007-07-19 David Delmarre Stable and palatable oral liquid sumatriptan compositions
US8492431B2 (en) 2005-12-19 2013-07-23 Janssen Pharmaceutica, N.V. Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US20070191461A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-heteroaryl sulfamide derivatives for the treatment of migraine
TW200812573A (en) 2006-05-19 2008-03-16 Janssen Pharmaceutica Nv Co-therapy for the treatment of epilepsy and related disorders
PL2124556T3 (pl) 2006-10-09 2015-02-27 Charleston Laboratories Inc Kompozycje farmaceutyczne
AU2007310949A1 (en) * 2006-10-19 2008-04-24 Auspex Pharmaceuticals, Inc. Substituted indoles
US20080275030A1 (en) 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
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US20090252791A1 (en) * 2008-04-02 2009-10-08 Venkata Nookaraju Sreedharala Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
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US8618157B2 (en) * 2008-06-20 2013-12-31 Alphapharm Pty. Ltd. Pharmaceutical formulation
BRPI0915890A2 (pt) 2008-06-23 2015-11-03 Janssen Pharmaceutica Nv forma cristalina de (2s)-(-)-n-(6-cloro-2,3-di-hidro-benzo[1,4]dioxin-2-ilmetil)-sulfamida
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US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
US9211282B2 (en) 2009-09-25 2015-12-15 Dr. Reddy's Laboratories Ltd. Formulations comprising triptan compounds
CN107530318A (zh) 2015-03-02 2018-01-02 阿福金制药有限责任公司 用大麻素的局部区域神经影响性疗法
US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
ES2842523T3 (es) 2015-05-15 2021-07-14 Univ Michigan Regents Métodos y composiciones para el tratamiento de la artritis
US10179109B2 (en) 2016-03-04 2019-01-15 Charleston Laboratories, Inc. Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates
US20180049994A1 (en) 2016-08-16 2018-02-22 Afgin Pharma, Llc Topical regional neuro-affective therapy with caryophyllene
CN117304172A (zh) 2017-11-07 2023-12-29 密执安大学评议会 化合物、药物组合物、其制备方法以及治疗疾病的方法
WO2020049523A1 (en) 2018-09-07 2020-03-12 Upsher-Smith Laboratories, Llc Methods of treating migraine
US11364225B2 (en) * 2019-08-21 2022-06-21 Bn Intellectual Properties, Inc. Pharmaceutical formulation for treating symptoms of migraine and cluster headaches, and method of using the same
AU2021227937A1 (en) * 2020-02-27 2022-09-08 Biohaven Pharmaceutical Holding Company Ltd. Oral fast-dispersing dosage form of rimegepant

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB8615599D0 (en) * 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
US5554639A (en) 1996-09-10
AP9100339A0 (en) 1992-01-31
GB2251614A (en) 1992-07-15
DE69108200T2 (de) 1995-07-20
KR100211479B1 (ko) 1999-08-02
CN1050831C (zh) 2000-03-29
NZ240942A (en) 1994-03-25
EP0490689B1 (en) 1995-03-15
PT99757A (pt) 1992-12-31
IS1706B (is) 1998-12-10
GB9026998D0 (en) 1991-01-30
ITRM910922A0 (it) 1991-12-11
CN1030890C (zh) 1996-02-07
DK0490689T3 (da) 1995-05-22
BE1005085A3 (fr) 1993-04-13
JPH06503560A (ja) 1994-04-21
PT99757B (pt) 1999-05-31
AU650706B2 (en) 1994-06-30
AU9072091A (en) 1992-07-08
TW300886B (is) 1997-03-21
CA2098302C (en) 2001-10-16
CN1128259A (zh) 1996-08-07
GR3015430T3 (en) 1995-06-30
CA2098302A1 (en) 1992-06-13
IL100330A0 (en) 1992-09-06
EP0490689A1 (en) 1992-06-17
TW205035B (is) 1993-05-01
RU2108328C1 (ru) 1998-04-10
IT1252868B (it) 1995-06-28
IL100330A (en) 1996-06-18
YU48926B (sh) 2002-12-10
GB2251614B (en) 1994-12-14
AP230A (en) 1993-01-27
MX9102501A (es) 1992-09-01
YU191491A (sh) 1994-04-05
ZA919750B (en) 1992-10-28
WO1992010477A1 (en) 1992-06-25
CH684192A5 (fr) 1994-07-29
ITRM910922A1 (it) 1993-06-11
DE69108200D1 (de) 1995-04-20
CN1063099A (zh) 1992-07-29
ES2069836T3 (es) 1995-05-16
MY109265A (en) 1996-12-31
US5705520A (en) 1998-01-06
GB9126297D0 (en) 1992-02-12
FR2670487B1 (fr) 1993-08-20
CZ114093A3 (en) 1994-02-16
IE62894B1 (en) 1995-03-08
FR2670487A1 (fr) 1992-06-19
HU211937A9 (en) 1996-01-29
IS3790A7 (is) 1992-06-13
HK82697A (en) 1997-06-27
IE914317A1 (en) 1992-06-17
CY2005A (en) 1997-12-05
CZ281931B6 (cs) 1997-04-16
ATE119881T1 (de) 1995-04-15
NL9102071A (nl) 1992-07-01
JP2994037B2 (ja) 1999-12-27

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