EG20219A - Method of preparation of deiwatives indole used in preparation of pharmaceutical composition and treatment of migraine - Google Patents

Method of preparation of deiwatives indole used in preparation of pharmaceutical composition and treatment of migraine

Info

Publication number
EG20219A
EG20219A EG75391A EG75391A EG20219A EG 20219 A EG20219 A EG 20219A EG 75391 A EG75391 A EG 75391A EG 75391 A EG75391 A EG 75391A EG 20219 A EG20219 A EG 20219A
Authority
EG
Egypt
Prior art keywords
preparation
deiwatives
migraine
treatment
pharmaceutical composition
Prior art date
Application number
EG75391A
Other languages
English (en)
Inventor
Joanne Craig
Derek Leslie Crookes
Stephen John Skittrall
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of EG20219A publication Critical patent/EG20219A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
EG75391A 1990-12-12 1991-12-11 Method of preparation of deiwatives indole used in preparation of pharmaceutical composition and treatment of migraine EG20219A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909026998A GB9026998D0 (en) 1990-12-12 1990-12-12 Medicaments

Publications (1)

Publication Number Publication Date
EG20219A true EG20219A (en) 1997-11-30

Family

ID=10686904

Family Applications (1)

Application Number Title Priority Date Filing Date
EG75391A EG20219A (en) 1990-12-12 1991-12-11 Method of preparation of deiwatives indole used in preparation of pharmaceutical composition and treatment of migraine

Country Status (36)

Country Link
US (2) US5554639A (fr)
EP (1) EP0490689B1 (fr)
JP (1) JP2994037B2 (fr)
KR (1) KR100211479B1 (fr)
CN (2) CN1030890C (fr)
AP (1) AP230A (fr)
AT (1) ATE119881T1 (fr)
AU (1) AU650706B2 (fr)
BE (1) BE1005085A3 (fr)
CA (1) CA2098302C (fr)
CH (1) CH684192A5 (fr)
CY (1) CY2005A (fr)
CZ (1) CZ281931B6 (fr)
DE (1) DE69108200T2 (fr)
DK (1) DK0490689T3 (fr)
EG (1) EG20219A (fr)
ES (1) ES2069836T3 (fr)
FR (1) FR2670487B1 (fr)
GB (2) GB9026998D0 (fr)
GR (1) GR3015430T3 (fr)
HK (1) HK82697A (fr)
HU (1) HU211937A9 (fr)
IE (1) IE62894B1 (fr)
IL (1) IL100330A (fr)
IS (1) IS1706B (fr)
IT (1) IT1252868B (fr)
MX (1) MX9102501A (fr)
MY (1) MY109265A (fr)
NL (1) NL9102071A (fr)
NZ (1) NZ240942A (fr)
PT (1) PT99757B (fr)
RU (1) RU2108328C1 (fr)
TW (2) TW300886B (fr)
WO (1) WO1992010477A1 (fr)
YU (1) YU48926B (fr)
ZA (1) ZA919750B (fr)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT71403A (en) * 1992-06-05 1995-11-28 Merck Sharp & Dohme The sulphate salt of a substituted triazole, pharmaceutical compositions thereof, and their use in therapy
FR2749846B1 (fr) * 1996-06-17 1998-09-11 Pf Medicament Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US8022095B2 (en) * 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US6106837A (en) * 1997-05-15 2000-08-22 Hirsch; Alan R. Method of treating headaches, and article of manufacture therefor
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US6426084B1 (en) * 2000-06-19 2002-07-30 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6132757A (en) * 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6187790B1 (en) 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
GB9926250D0 (en) * 1999-11-06 2000-01-12 Knoll Ag Chemical process
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US6610271B2 (en) * 2000-05-10 2003-08-26 University Of Kentucky Research Foundation System and method for intranasal administration of lorazepam
US6458804B1 (en) 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US6562838B2 (en) * 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
US20030096748A1 (en) * 2001-06-04 2003-05-22 The Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US8329734B2 (en) 2009-07-27 2012-12-11 Afgin Pharma Llc Topical therapy for migraine
EP1435945B1 (fr) * 2001-06-05 2008-08-13 Aung-din, Ronald Therapie antimigraineuse par voie topique
US7041677B2 (en) * 2002-03-01 2006-05-09 R.T. Alamo Ventures I, Llc Use of monochloroflosequinan in the treatment of sexual dysfunction
US7208628B2 (en) * 2002-05-13 2007-04-24 Kansas State University Research Foundation Compositions and methods for the treatment of hepatitis C virus infection
US7074893B2 (en) * 2002-06-03 2006-07-11 Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
EP1575566B1 (fr) * 2002-12-26 2012-02-22 Pozen, Inc. Formes galeniques multicouches contenant de naproxene et des triptanes
US20080213363A1 (en) * 2003-01-23 2008-09-04 Singh Nikhilesh N Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa
WO2004076403A1 (fr) * 2003-02-24 2004-09-10 Transform Pharmaceuticals, Inc. Formes cristallines du sumatriptan, compositions pharmaceutiques et procedes
WO2004112723A2 (fr) 2003-06-20 2004-12-29 Ronald Aung-Din Therapie locale pour le traitement des migraines, des claquages musculaires, des spasmes musculaires, de la spasticite et d'etats apparentes
US20050089558A1 (en) * 2003-10-28 2005-04-28 Alamo Pharmaceuticals, Llc Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
WO2005119607A2 (fr) * 2004-06-03 2005-12-15 Tyfone, Inc. Systeme et procede pour securiser pour des transactions financieres
WO2005123043A2 (fr) * 2004-06-10 2005-12-29 Duramed Pharmaceuticals, Inc. Formulations de sumatriptan absorbables au travers des membranes biologiques, et methodes de production et d'utilisation desdites formulations
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
CA2609185A1 (fr) 2005-05-20 2006-11-30 Ahmed F. Abdel-Magid Procede de fabrication de derives de sulfamide
US20070166336A1 (en) * 2005-12-13 2007-07-19 David Delmarre Stable and palatable oral liquid sumatriptan compositions
AR058389A1 (es) 2005-12-19 2008-01-30 Janssen Pharmaceutica Nv Uso de derivados heterociclicos benzo-fusionados de sulfamida para el tratamiento de la obesidad
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US20070191461A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-heteroaryl sulfamide derivatives for the treatment of migraine
EP2026790A2 (fr) 2006-05-19 2009-02-25 Janssen Pharmaceutica, N.V. Thérapie combinée pour le traitement de l'épilepsie et de troubles apparentés
SI2124556T1 (sl) 2006-10-09 2015-01-30 Charleston Laboratories, Inc. Farmacevtske sestave
CA2666149A1 (fr) * 2006-10-19 2008-04-24 Auspex Pharmaceuticals, Inc. Indoles substitues
US20080275030A1 (en) * 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
GB2448183A (en) * 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
US8124126B2 (en) 2008-01-09 2012-02-28 Charleston Laboratories, Inc. Pharmaceutical compositions
US20090252791A1 (en) * 2008-04-02 2009-10-08 Venkata Nookaraju Sreedharala Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
CN102046621B (zh) 2008-05-27 2014-11-12 生物区科学管理控股有限公司 抗病毒盐
CN102088966B (zh) * 2008-06-20 2015-06-10 阿尔法制药有限公司 药物制剂
MX2011000090A (es) 2008-06-23 2011-03-02 Janssen Pharmaceutica Nv Forma cristalina de (2s)-(-)-n-(6-cloro-2,3-dihidro-benzo[1,4]diox in-2-ilmetil)sulfamida.
AU2009269129B2 (en) * 2008-06-30 2015-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy
US8815939B2 (en) 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
EP2451274B1 (fr) 2009-07-08 2017-10-04 Charleston Laboratories, Inc. Compositions pharmaceutiques
AU2010299607B2 (en) 2009-09-25 2016-07-28 Tonix Medicines, Inc. Formulations comprising triptan compounds
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
CN107530318A (zh) 2015-03-02 2018-01-02 阿福金制药有限责任公司 用大麻素的局部区域神经影响性疗法
US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
ES2842523T3 (es) 2015-05-15 2021-07-14 Univ Michigan Regents Métodos y composiciones para el tratamiento de la artritis
JP2019507181A (ja) 2016-03-04 2019-03-14 チャールストン ラボラトリーズ，インコーポレイテッド 医薬組成物
US20180049994A1 (en) 2016-08-16 2018-02-22 Afgin Pharma, Llc Topical regional neuro-affective therapy with caryophyllene
CN117304172A (zh) 2017-11-07 2023-12-29 密执安大学评议会 化合物、药物组合物、其制备方法以及治疗疾病的方法
WO2020049523A1 (fr) 2018-09-07 2020-03-12 Upsher-Smith Laboratories, Llc Méthodes de traitement de la migraine
US11364225B2 (en) * 2019-08-21 2022-06-21 Bn Intellectual Properties, Inc. Pharmaceutical formulation for treating symptoms of migraine and cluster headaches, and method of using the same
BR112022016790A2 (pt) * 2020-02-27 2022-11-08 Biohaven Pharm Holding Co Ltd Forma de dosagem oral de dispersão rápida de rimegepant

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB8615599D0 (en) * 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
CA2098302C (fr) 2001-10-16
AP230A (en) 1993-01-27
CN1050831C (zh) 2000-03-29
GB2251614B (en) 1994-12-14
BE1005085A3 (fr) 1993-04-13
CH684192A5 (fr) 1994-07-29
IS3790A7 (is) 1992-06-13
GB9026998D0 (en) 1991-01-30
CZ281931B6 (cs) 1997-04-16
RU2108328C1 (ru) 1998-04-10
KR100211479B1 (ko) 1999-08-02
ES2069836T3 (es) 1995-05-16
HU211937A9 (en) 1996-01-29
DE69108200T2 (de) 1995-07-20
WO1992010477A1 (fr) 1992-06-25
IT1252868B (it) 1995-06-28
DK0490689T3 (da) 1995-05-22
AU9072091A (en) 1992-07-08
CN1128259A (zh) 1996-08-07
NL9102071A (nl) 1992-07-01
GB9126297D0 (en) 1992-02-12
ATE119881T1 (de) 1995-04-15
MX9102501A (es) 1992-09-01
JP2994037B2 (ja) 1999-12-27
TW205035B (fr) 1993-05-01
IS1706B (is) 1998-12-10
CN1030890C (zh) 1996-02-07
YU191491A (sh) 1994-04-05
IE62894B1 (en) 1995-03-08
PT99757A (pt) 1992-12-31
PT99757B (pt) 1999-05-31
AU650706B2 (en) 1994-06-30
GR3015430T3 (en) 1995-06-30
CZ114093A3 (en) 1994-02-16
US5554639A (en) 1996-09-10
IL100330A (en) 1996-06-18
NZ240942A (en) 1994-03-25
ITRM910922A0 (it) 1991-12-11
DE69108200D1 (de) 1995-04-20
AP9100339A0 (en) 1992-01-31
MY109265A (en) 1996-12-31
CY2005A (en) 1997-12-05
IE914317A1 (en) 1992-06-17
YU48926B (sh) 2002-12-10
ITRM910922A1 (it) 1993-06-11
CN1063099A (zh) 1992-07-29
ZA919750B (en) 1992-10-28
CA2098302A1 (fr) 1992-06-13
FR2670487A1 (fr) 1992-06-19
IL100330A0 (en) 1992-09-06
EP0490689A1 (fr) 1992-06-17
JPH06503560A (ja) 1994-04-21
TW300886B (fr) 1997-03-21
US5705520A (en) 1998-01-06
EP0490689B1 (fr) 1995-03-15
HK82697A (en) 1997-06-27
GB2251614A (en) 1992-07-15
FR2670487B1 (fr) 1993-08-20

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