EG17344A - Process for preparing a quinoline intropic agents - Google Patents

Process for preparing a quinoline intropic agents

Info

Publication number
EG17344A
EG17344A EG323/85A EG32385A EG17344A EG 17344 A EG17344 A EG 17344A EG 323/85 A EG323/85 A EG 323/85A EG 32385 A EG32385 A EG 32385A EG 17344 A EG17344 A EG 17344A
Authority
EG
Egypt
Prior art keywords
intropic
quinoline
agents
preparing
quinoline intropic
Prior art date
Application number
EG323/85A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848413685A external-priority patent/GB8413685D0/en
Priority claimed from GB848427167A external-priority patent/GB8427167D0/en
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of EG17344A publication Critical patent/EG17344A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
EG323/85A 1984-05-29 1985-05-28 Process for preparing a quinoline intropic agents EG17344A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848413685A GB8413685D0 (en) 1984-05-29 1984-05-29 Quinolone inotropic agents
GB848427167A GB8427167D0 (en) 1984-10-26 1984-10-26 Quinoline inotropic agents

Publications (1)

Publication Number Publication Date
EG17344A true EG17344A (en) 1991-08-30

Family

ID=26287793

Family Applications (1)

Application Number Title Priority Date Filing Date
EG323/85A EG17344A (en) 1984-05-29 1985-05-28 Process for preparing a quinoline intropic agents

Country Status (18)

Country Link
US (3) US4728653A (fi)
EP (1) EP0166533B1 (fi)
KR (1) KR870001167B1 (fi)
AU (1) AU562081B2 (fi)
CA (1) CA1292234C (fi)
DE (1) DE3577091D1 (fi)
DK (1) DK236085A (fi)
EG (1) EG17344A (fi)
ES (1) ES8608874A1 (fi)
FI (1) FI852123L (fi)
GR (1) GR851296B (fi)
HU (1) HU195961B (fi)
IL (1) IL75326A (fi)
NO (1) NO163186B (fi)
NZ (1) NZ212209A (fi)
PL (1) PL145325B1 (fi)
PT (1) PT80533B (fi)
YU (1) YU44774B (fi)

Families Citing this family (39)

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ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
GB8502267D0 (en) * 1985-01-30 1985-02-27 Pfizer Ltd Quinolone inotropic agents
DK111387A (da) * 1986-03-05 1987-09-06 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
US5358949A (en) * 1986-03-05 1994-10-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives
US4792561A (en) * 1986-05-29 1988-12-20 Syntex (U.S.A.) Inc. Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors
GB8619902D0 (en) * 1986-08-15 1986-09-24 Pfizer Ltd Quinolone cardiac stimulants
GB8630702D0 (en) * 1986-12-23 1987-02-04 Wellcome Found Quinoline compound
US5166160A (en) * 1986-12-23 1992-11-24 Burroughs Wellcome Co. Quinoline compound
GB8709448D0 (en) * 1987-04-21 1987-05-28 Pfizer Ltd Heterobicyclic quinoline derivatives
DE3819565A1 (de) * 1988-06-09 1990-04-12 Hoechst Ag Verfahren zur herstellung von 4-nitro-3-trifluormethyl-anilin
CA2015366C (en) * 1989-05-05 2001-09-11 Rhone-Poulenc Agrochimie Pesticidal 1-arylimidazoles
US5223525A (en) * 1989-05-05 1993-06-29 Rhone-Poulenc Ag Company Pesticidal 1-arylimidazoles
KR0164842B1 (ko) * 1990-03-24 1999-01-15 손정삼 신규 벤즈옥사진, 벤조티아진 유도체 및 그 제조방법
US5200419A (en) * 1990-05-21 1993-04-06 Warner-Lambert Company Substituted tetrazoles and derivatives thereof acting at muscarinic receptors
EP0510235A1 (en) * 1991-04-26 1992-10-28 Dong-A Pharm. Co., Ltd. Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same
JP2686887B2 (ja) * 1992-08-11 1997-12-08 キッセイ薬品工業株式会社 ピペリジノ−3,4−ジヒドロカルボスチリル誘導体
US5958926A (en) * 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
AU751139B2 (en) * 1997-10-13 2002-08-08 Astellas Pharma Inc. Amide derivative
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6566372B1 (en) * 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
JP2003508402A (ja) 1999-08-27 2003-03-04 リガンド・ファーマシューティカルズ・インコーポレイテッド アンドロゲン受容体モジュレーター化合物および方法
WO2001016133A2 (en) 1999-08-27 2001-03-08 Ligand Pharmaceuticals Incorporated 8-substituted-6-trifluoromethyl-9-pyrido[3,2-g]quinoline compounds as androgen receptor modulators
JP2003529545A (ja) 1999-09-14 2003-10-07 リガンド・ファーマシューティカルズ・インコーポレイテッド 改善された薬理学的プロファイルを有するrxrモジュレーター
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
WO2003002121A1 (en) * 2001-06-29 2003-01-09 Aaipharma, Inc. Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetrazol-5-yl)butoxy]-3, 4-dihydro-2(1h)-quinolinone
US6660864B2 (en) * 2001-06-29 2003-12-09 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
WO2003002529A2 (en) * 2001-06-29 2003-01-09 Aaipharma, Inc. Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetrazol-5-yl)butoxy]-3, 4-dihydro-2(1h)-quinolinone
US6531603B1 (en) 2001-06-29 2003-03-11 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
WO2003002120A1 (en) * 2001-06-29 2003-01-09 Aaipharma, Inc. Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetrazol-5-yl)butoxy]-3, 4-dihydro-2(1h)-quinolinone
US6573382B2 (en) * 2001-06-29 2003-06-03 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6596871B2 (en) * 2001-06-29 2003-07-22 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetraol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6657061B2 (en) * 2001-06-29 2003-12-02 Grayson Walker Stowell Polymorphic forms of 6-[4-1(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6388080B1 (en) 2001-06-29 2002-05-14 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
BRPI0413820A (pt) * 2003-08-22 2006-10-24 Ligand Pharm Inc derivados de 6-cicloamino-2-quinolinona como compostos moduladores de receptor de androgênio
MY146795A (en) * 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
AU2013205820B2 (en) * 2005-06-09 2015-11-26 Novartis Ag Process for the synthesis of organic compounds
KR20100058660A (ko) * 2007-10-23 2010-06-03 테바 파마슈티컬 인더스트리즈 리미티드 다사티닙 다형체 및 이의 제조 방법
EP3679028A1 (en) * 2017-09-04 2020-07-15 C4 Therapeutics, Inc. Dihydroquinolinones

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Publication number Priority date Publication date Assignee Title
US3993656A (en) * 1974-11-19 1976-11-23 Merck & Co., Inc. 1,8-Naphthyridine compounds
JPS5473783A (en) * 1977-11-15 1979-06-13 Otsuka Pharmaceut Co Ltd Pyridine derivative
DE2815956A1 (de) * 1978-04-13 1979-10-18 Bayer Ag Verfahren zur herstellung von in 2-stellung substituierten triazolen-1,2,3
JPS5535019A (en) * 1978-09-01 1980-03-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
JPS5576872A (en) * 1978-12-06 1980-06-10 Yoshitomi Pharmaceut Ind Ltd Imidazolidinone derivative
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
CA1164459A (en) * 1980-11-11 1984-03-27 Yung-Hsiung Yang Process for preparing (imidazo¬1,2-a|pyridine- 2-yl)-carbostyril or -3,4-dihydrocarbostyryl derivatives
US4432979A (en) * 1981-10-26 1984-02-21 William H. Rorer, Inc. Pyridone compounds
EP0102046A1 (en) * 1982-08-26 1984-03-07 Schering Corporation Tricyclic lactams, method for making them, pharmaceutical compositions containing them
CH655110A5 (de) * 1982-09-03 1986-03-27 Otsuka Pharma Co Ltd Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten.
PT79031B (en) * 1983-08-20 1986-08-22 Boots Co Plc Therapeutic agents
US4532250A (en) * 1983-11-23 1985-07-30 American Hospital Supply Corporation 5-Heteroarylimidazol-2-ones having cardiotonic activity
US4710507A (en) * 1983-12-22 1987-12-01 Pfizer Inc. Quinolone inotropic agents
US4591591A (en) * 1984-03-08 1986-05-27 Eli Lilly And Company Pyridazinone derivatives as inotropic agents

Also Published As

Publication number Publication date
EP0166533A1 (en) 1986-01-02
KR870001167B1 (ko) 1987-06-15
NZ212209A (en) 1988-08-30
NO163186B (no) 1990-01-08
CA1292234C (en) 1991-11-19
PT80533A (en) 1985-06-01
ES543514A0 (es) 1986-09-01
FI852123A0 (fi) 1985-05-28
KR850008675A (ko) 1985-12-21
IL75326A (en) 1988-09-30
HUT40642A (en) 1987-01-28
HU195961B (en) 1988-08-29
YU44774B (en) 1991-02-28
US4900839A (en) 1990-02-13
IL75326A0 (en) 1985-09-29
US4837334A (en) 1989-06-06
GR851296B (fi) 1985-11-25
PT80533B (en) 1987-04-06
DK236085A (da) 1985-11-30
DE3577091D1 (en) 1990-05-17
YU88985A (en) 1987-12-31
PL145325B1 (en) 1988-09-30
AU562081B2 (en) 1987-05-28
EP0166533B1 (en) 1990-04-11
ES8608874A1 (es) 1986-09-01
PL253689A1 (en) 1986-07-01
US4728653A (en) 1988-03-01
NO852124L (no) 1985-12-02
AU4303285A (en) 1985-12-05
FI852123L (fi) 1985-11-30
DK236085D0 (da) 1985-05-28

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