DK236085A - Heterocyclisk substituerede 2(ah)-quinolon-forbindelser og forbindelser til anvendelse som mellemprodukter ved deres fremstilling samt farmaceutiske praeparater - Google Patents

Heterocyclisk substituerede 2(ah)-quinolon-forbindelser og forbindelser til anvendelse som mellemprodukter ved deres fremstilling samt farmaceutiske praeparater Download PDF

Info

Publication number
DK236085A
DK236085A DK236085A DK236085A DK236085A DK 236085 A DK236085 A DK 236085A DK 236085 A DK236085 A DK 236085A DK 236085 A DK236085 A DK 236085A DK 236085 A DK236085 A DK 236085A
Authority
DK
Denmark
Prior art keywords
quinolon
intermediates
compounds
preparation
pharmaceutical preparations
Prior art date
Application number
DK236085A
Other languages
English (en)
Other versions
DK236085D0 (da
Inventor
David Anthony Roberts
Simon Fraser Campbell
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848413685A external-priority patent/GB8413685D0/en
Priority claimed from GB848427167A external-priority patent/GB8427167D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of DK236085D0 publication Critical patent/DK236085D0/da
Publication of DK236085A publication Critical patent/DK236085A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
DK236085A 1984-05-29 1985-05-28 Heterocyclisk substituerede 2(ah)-quinolon-forbindelser og forbindelser til anvendelse som mellemprodukter ved deres fremstilling samt farmaceutiske praeparater DK236085A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848413685A GB8413685D0 (en) 1984-05-29 1984-05-29 Quinolone inotropic agents
GB848427167A GB8427167D0 (en) 1984-10-26 1984-10-26 Quinoline inotropic agents

Publications (2)

Publication Number Publication Date
DK236085D0 DK236085D0 (da) 1985-05-28
DK236085A true DK236085A (da) 1985-11-30

Family

ID=26287793

Family Applications (1)

Application Number Title Priority Date Filing Date
DK236085A DK236085A (da) 1984-05-29 1985-05-28 Heterocyclisk substituerede 2(ah)-quinolon-forbindelser og forbindelser til anvendelse som mellemprodukter ved deres fremstilling samt farmaceutiske praeparater

Country Status (18)

Country Link
US (3) US4728653A (da)
EP (1) EP0166533B1 (da)
KR (1) KR870001167B1 (da)
AU (1) AU562081B2 (da)
CA (1) CA1292234C (da)
DE (1) DE3577091D1 (da)
DK (1) DK236085A (da)
EG (1) EG17344A (da)
ES (1) ES8608874A1 (da)
FI (1) FI852123L (da)
GR (1) GR851296B (da)
HU (1) HU195961B (da)
IL (1) IL75326A (da)
NO (1) NO163186B (da)
NZ (1) NZ212209A (da)
PL (1) PL145325B1 (da)
PT (1) PT80533B (da)
YU (1) YU44774B (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735948A (en) * 1983-03-25 1988-04-05 Merrell Dow Pharmaceuticals Inc. (1H-tetrazol-5-yl)-2(1H)-quinolinones and-naphthyridones and antiallergic use thereof
ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
GB8502267D0 (en) * 1985-01-30 1985-02-27 Pfizer Ltd Quinolone inotropic agents
US5358949A (en) * 1986-03-05 1994-10-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives
DK111387A (da) * 1986-03-05 1987-09-06 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
US4792561A (en) * 1986-05-29 1988-12-20 Syntex (U.S.A.) Inc. Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors
GB8619902D0 (en) * 1986-08-15 1986-09-24 Pfizer Ltd Quinolone cardiac stimulants
GB8630702D0 (en) * 1986-12-23 1987-02-04 Wellcome Found Quinoline compound
US5166160A (en) * 1986-12-23 1992-11-24 Burroughs Wellcome Co. Quinoline compound
GB8709448D0 (en) * 1987-04-21 1987-05-28 Pfizer Ltd Heterobicyclic quinoline derivatives
DE3819565A1 (de) * 1988-06-09 1990-04-12 Hoechst Ag Verfahren zur herstellung von 4-nitro-3-trifluormethyl-anilin
CA2015366C (en) * 1989-05-05 2001-09-11 Rhone-Poulenc Agrochimie Pesticidal 1-arylimidazoles
US5223525A (en) * 1989-05-05 1993-06-29 Rhone-Poulenc Ag Company Pesticidal 1-arylimidazoles
KR0164842B1 (ko) * 1990-03-24 1999-01-15 손정삼 신규 벤즈옥사진, 벤조티아진 유도체 및 그 제조방법
US5200419A (en) * 1990-05-21 1993-04-06 Warner-Lambert Company Substituted tetrazoles and derivatives thereof acting at muscarinic receptors
EP0510235A1 (en) * 1991-04-26 1992-10-28 Dong-A Pharm. Co., Ltd. Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same
JP2686887B2 (ja) * 1992-08-11 1997-12-08 キッセイ薬品工業株式会社 ピペリジノ−３，４−ジヒドロカルボスチリル誘導体
US5958926A (en) * 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
AU751139B2 (en) * 1997-10-13 2002-08-08 Astellas Pharma Inc. Amide derivative
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
PL353792A1 (en) 1999-08-27 2003-12-01 Ligand Pharmaceuticals Incorporatedligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
CA2378298A1 (en) 1999-08-27 2001-03-08 Lawrence G. Hamann 8-substituted-6-trifluoromethyl-9-pyrido¬3,2-g|quinoline compounds as androgen receptor modulators
US6566372B1 (en) * 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
CA2383565A1 (en) 1999-09-14 2001-03-22 Ligand Pharmaceuticals Incorporated Rxr modulators with improved pharmacologic profile
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
US6388080B1 (en) 2001-06-29 2002-05-14 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6531603B1 (en) 2001-06-29 2003-03-11 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6657061B2 (en) * 2001-06-29 2003-12-02 Grayson Walker Stowell Polymorphic forms of 6-[4-1(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
WO2003002121A1 (en) * 2001-06-29 2003-01-09 Aaipharma, Inc. Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetrazol-5-yl)butoxy]-3, 4-dihydro-2(1h)-quinolinone
US6573382B2 (en) * 2001-06-29 2003-06-03 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6660864B2 (en) * 2001-06-29 2003-12-09 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6596871B2 (en) * 2001-06-29 2003-07-22 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetraol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
WO2003002529A2 (en) * 2001-06-29 2003-01-09 Aaipharma, Inc. Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetrazol-5-yl)butoxy]-3, 4-dihydro-2(1h)-quinolinone
WO2003002120A1 (en) * 2001-06-29 2003-01-09 Aaipharma, Inc. Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetrazol-5-yl)butoxy]-3, 4-dihydro-2(1h)-quinolinone
CA2536349A1 (en) * 2003-08-22 2005-03-03 Ligand Pharmaceuticals Incorporated 6-cycloamino-2-quinolinone derivatives as androgen receptor modulator compounds
AU2013205820B2 (en) * 2005-06-09 2015-11-26 Novartis Ag Process for the synthesis of organic compounds
MY146795A (en) * 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
KR20120033357A (ko) * 2007-10-23 2012-04-06 테바 파마슈티컬 인더스트리즈 리미티드 다사티닙 다형체 및 이의 제조 방법
EP3679028A1 (en) * 2017-09-04 2020-07-15 C4 Therapeutics, Inc. Dihydroquinolinones

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993656A (en) * 1974-11-19 1976-11-23 Merck & Co., Inc. 1,8-Naphthyridine compounds
JPS5473783A (en) * 1977-11-15 1979-06-13 Otsuka Pharmaceut Co Ltd Pyridine derivative
DE2815956A1 (de) * 1978-04-13 1979-10-18 Bayer Ag Verfahren zur herstellung von in 2-stellung substituierten triazolen-1,2,3
JPS5535019A (en) * 1978-09-01 1980-03-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
JPS5576872A (en) * 1978-12-06 1980-06-10 Yoshitomi Pharmaceut Ind Ltd Imidazolidinone derivative
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
CA1164459A (en) * 1980-11-11 1984-03-27 Yung-Hsiung Yang Process for preparing (imidazo¬1,2-a|pyridine- 2-yl)-carbostyril or -3,4-dihydrocarbostyryl derivatives
US4432979A (en) * 1981-10-26 1984-02-21 William H. Rorer, Inc. Pyridone compounds
EP0102046A1 (en) * 1982-08-26 1984-03-07 Schering Corporation Tricyclic lactams, method for making them, pharmaceutical compositions containing them
CH655110A5 (de) * 1982-09-03 1986-03-27 Otsuka Pharma Co Ltd Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten.
PT79031B (en) * 1983-08-20 1986-08-22 Boots Co Plc Therapeutic agents
US4532250A (en) * 1983-11-23 1985-07-30 American Hospital Supply Corporation 5-Heteroarylimidazol-2-ones having cardiotonic activity
US4710507A (en) * 1983-12-22 1987-12-01 Pfizer Inc. Quinolone inotropic agents
US4591591A (en) * 1984-03-08 1986-05-27 Eli Lilly And Company Pyridazinone derivatives as inotropic agents

Also Published As

Publication number Publication date
KR850008675A (ko) 1985-12-21
KR870001167B1 (ko) 1987-06-15
IL75326A0 (en) 1985-09-29
AU4303285A (en) 1985-12-05
EP0166533B1 (en) 1990-04-11
US4728653A (en) 1988-03-01
ES543514A0 (es) 1986-09-01
PT80533B (en) 1987-04-06
PT80533A (en) 1985-06-01
FI852123A0 (fi) 1985-05-28
CA1292234C (en) 1991-11-19
DE3577091D1 (en) 1990-05-17
YU88985A (en) 1987-12-31
IL75326A (en) 1988-09-30
PL253689A1 (en) 1986-07-01
DK236085D0 (da) 1985-05-28
HU195961B (en) 1988-08-29
US4837334A (en) 1989-06-06
AU562081B2 (en) 1987-05-28
EP0166533A1 (en) 1986-01-02
NZ212209A (en) 1988-08-30
NO852124L (no) 1985-12-02
FI852123L (fi) 1985-11-30
ES8608874A1 (es) 1986-09-01
EG17344A (en) 1991-08-30
GR851296B (da) 1985-11-25
PL145325B1 (en) 1988-09-30
YU44774B (en) 1991-02-28
HUT40642A (en) 1987-01-28
NO163186B (no) 1990-01-08
US4900839A (en) 1990-02-13

Similar Documents

Publication Publication Date Title
DK236085A (da) Heterocyclisk substituerede 2(ah)-quinolon-forbindelser og forbindelser til anvendelse som mellemprodukter ved deres fremstilling samt farmaceutiske praeparater
DK422485A (da) 1,3-diacyl-2-oxindol-forbindelser og mellemprodukter ved deres fremstilling samt farmaceutiske praeparater
DK289487A (da) Farmaceutiske praeparater til topisk applikation samt deres fremstilling og anvendelse
DK142485D0 (da) Acyltripeptider, mellemprodukter ved deres fremstilling og farmaceutiske praeparater
DK214088A (da) Ae6-heterobiskcyclisk substituerede 2(1h)-quinolon-forbindelser og deres anvendelse som hjertestimulerende midler samt farmaceutiske praeparater indeholdende disseae
DK328585D0 (da) Modificerede succinimider, fremgangsmaade til deres fremstilling samt deres anvendelse
DK335686D0 (da) Fremgangsmaade til fremstilling af 1-carba-3-cephem-4-carboxylsyrer ogderivater deraf samt mellemprodukter til brug ved fremgangsmaaden
DK534286D0 (da) Nicotinsyrederivater, deres fremstilling og anvendelse som herbicider samt mellemprodukter ved fremstillingen og disses fremstilling
DK394489A (da) I para-stillingen heterocyclisk substituerede n-phenylamidforbindelser, mellemprodukter ved deres fremstilling, farmaceutiske praeparater indeholdende forbindelserne og anvendelse af forbindelserne til fremstilling af antiarytmiske laegemidler
DK568285A (da) 1,4-dihydropyridiner, deres fremstilling og mellemprodukter hertil samt deres anvendelse som laegemidler
DK147386D0 (da) Derivater af methylen-bisphosphonsyre, fremgangsmaade til fremstillingaf samme samt farmaceutisk sammensaetning
DK43685D0 (da) Benzobicycliske lactamsyrer og derivater deraf, fremgangsmaade til deres fremstilling samt deres anvendelse
DK408186D0 (da) Podophyllotoxin og derivater deraf, fremgangsmaader til deres fremstilling og anvendelse samt farmaceutiske praeparater indeholdende forbindelserne
DK325487D0 (da) Farmaceutiske sammensaetninger til parenteral applikation samt deres fremstilling
DK170986A (da) Substituerede 2,3,4,9-tetrahydro-1h-carbazol-1-eddikesyre-derivater, deres fremstilling og anvendelse som famaceutika samt mellem-produkter ved fremstillingen
DK494589D0 (da) Substituerede 1,3,5-triazintrioner og deres anvendelse samt mellemprodukter til deres fremstilling
DK477685A (da) Peptidsubstituerede heterocycliske forbindelser og anvendelse deraf som immunostimulerende eller antiinfektive forbindelser samt farmaceutiske praeparater
DK488385A (da) N6-bicycloadenosinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende saadanne forbindelser
DK177489D0 (da) Cholestadienderivater som mellemprodukter til brug ved fremstillingen af homovitamin-d3-derivater
DK481485A (da) 6-substituerede penicillansyre-1,1-dioxid-forbindelser og mellemprodukter ved deres fremstilling samt farmaceutiske praeparater
DK202286D0 (da) Dihydropyridin-forbindelser og deres anvendelse til fremstilling af antiisohaemiske eller antihypertensive midler samt farmaceutiske praeparater indeholdende forbindelserne
DK402585A (da) Pseudooligosaccharider med alfa-glucosidase-inhiberende virkning, deres fremstilling og anvendelse samt farmaceutiske praeparater
DK47488A (da) Pesticid indeholdende pyrimidinderivater samt pyrimidinderivater og fremgangsmaade til deres fremstilling
DK361185D0 (da) 2-aminoalkyl-2-penem-forbindelser samt deres fremstilling og anvendelse
DK127086A (da) Substituerede 1,8-naphthyridoner, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner, der indeholder disse forbindelser

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment