EG12261A - Method for preparing of substituted n-methylene of thienamycin - Google Patents

Method for preparing of substituted n-methylene of thienamycin

Info

Publication number
EG12261A
EG12261A EG76723A EG72376A EG12261A EG 12261 A EG12261 A EG 12261A EG 76723 A EG76723 A EG 76723A EG 72376 A EG72376 A EG 72376A EG 12261 A EG12261 A EG 12261A
Authority
EG
Egypt
Prior art keywords
thienamycin
methylene
substituted
preparing
Prior art date
Application number
EG76723A
Other languages
English (en)
Inventor
B Christensen
W Leanze
K Wildonger
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of EG12261A publication Critical patent/EG12261A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EG76723A 1975-11-21 1976-11-21 Method for preparing of substituted n-methylene of thienamycin EG12261A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63429675A 1975-11-21 1975-11-21
US67626176A 1976-04-12 1976-04-12
US73365476A 1976-10-18 1976-10-18

Publications (1)

Publication Number Publication Date
EG12261A true EG12261A (en) 1978-12-31

Family

ID=27417545

Family Applications (1)

Application Number Title Priority Date Filing Date
EG76723A EG12261A (en) 1975-11-21 1976-11-21 Method for preparing of substituted n-methylene of thienamycin

Country Status (27)

Country Link
AT (1) AT358168B (sv)
AU (1) AU512383B2 (sv)
BG (1) BG34037A3 (sv)
CA (1) CA1083577A (sv)
CH (2) CH632510A5 (sv)
DD (1) DD127742A5 (sv)
DE (1) DE2652679A1 (sv)
DK (1) DK157401C (sv)
EG (1) EG12261A (sv)
ES (1) ES453501A1 (sv)
FI (1) FI62306C (sv)
FR (1) FR2332012A1 (sv)
GB (1) GB1570990A (sv)
GR (1) GR62072B (sv)
HK (1) HK29683A (sv)
HU (1) HU180865B (sv)
IE (1) IE44433B1 (sv)
IL (1) IL50911A (sv)
KE (1) KE3286A (sv)
NL (1) NL189297C (sv)
NO (1) NO153298C (sv)
NZ (1) NZ182630A (sv)
PH (1) PH16714A (sv)
PL (1) PL110937B1 (sv)
PT (1) PT65865B (sv)
SE (1) SE427841B (sv)
SG (1) SG10983G (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
DK170778A (da) * 1977-05-05 1979-01-15 Merck & Co Inc Fremgangsmaade til fremstilling af n-alkyl-n-iminomethyl-derivater af thienamycin
US4232030A (en) * 1977-09-15 1980-11-04 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone
DK153486C (da) * 1978-07-03 1988-11-28 Merck & Co Inc Analogifremgangsmaade til fremstilling af krystallinsk n-formimidoyl-thienamycin-monohydrat
EP0044170A1 (en) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-lactam antibiotics, their preparation and use
CA2089261A1 (en) * 1990-08-30 1992-03-01 John F.W. Keana Substituted amidines having high binding to the sigma receptor and the use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348985A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Esters of cephalosporin compounds
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
FI62306B (fi) 1982-08-31
IL50911A (en) 1981-01-30
GR62072B (en) 1979-02-20
IE44433L (en) 1977-05-21
HU180865B (en) 1983-04-29
FR2332012B1 (sv) 1978-11-17
AU1964776A (en) 1978-05-25
KE3286A (en) 1983-06-17
DE2652679A1 (de) 1977-06-02
NO153298B (no) 1985-11-11
PT65865B (en) 1978-10-12
DD127742A5 (de) 1977-10-12
NZ182630A (en) 1979-07-11
GB1570990A (en) 1980-07-09
SE7612963L (sv) 1977-05-22
DK157401C (da) 1990-05-21
DK523576A (da) 1977-05-22
SG10983G (en) 1983-12-16
AT358168B (de) 1980-08-25
PL110937B1 (en) 1980-08-30
DE2652679C2 (sv) 1990-03-01
BG34037A3 (en) 1983-06-15
FI62306C (fi) 1982-12-10
NO763958L (sv) 1977-05-24
PL193809A1 (pl) 1978-01-16
DK157401B (da) 1990-01-02
FI763308A (sv) 1977-05-22
HK29683A (en) 1983-08-26
IE44433B1 (en) 1981-12-02
NL189297B (nl) 1992-10-01
NL189297C (nl) 1993-03-01
NO153298C (no) 1986-02-19
PH16714A (en) 1984-01-25
CA1083577A (en) 1980-08-12
CH633800A5 (en) 1982-12-31
SE427841B (sv) 1983-05-09
ATA863476A (de) 1980-01-15
IL50911A0 (en) 1977-01-31
FR2332012A1 (fr) 1977-06-17
NL7612939A (nl) 1977-05-24
AU512383B2 (en) 1980-10-09
ES453501A1 (es) 1978-03-01
CH632510A5 (en) 1982-10-15
PT65865A (en) 1976-12-01

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