EE9900038A - Fluori sisaldavad 1,4-diasendatud piperidiini derivaadid - Google Patents

Fluori sisaldavad 1,4-diasendatud piperidiini derivaadid

Info

Publication number
EE9900038A
EE9900038A EEP199900038A EE9900038A EE9900038A EE 9900038 A EE9900038 A EE 9900038A EE P199900038 A EEP199900038 A EE P199900038A EE 9900038 A EE9900038 A EE 9900038A EE 9900038 A EE9900038 A EE 9900038A
Authority
EE
Estonia
Prior art keywords
fluoride
piperidine derivatives
disubstituted piperidine
disubstituted
derivatives
Prior art date
Application number
EEP199900038A
Other languages
English (en)
Estonian (et)
Inventor
Tsuchiya Yoshimi
Nomoto Takashi
Ohsawa Hirokazu
Kawakami Kumiko
Ohwaki Kenji
Nishikibe Masaru
Original Assignee
Banyu Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharmaceutical Co., Ltd. filed Critical Banyu Pharmaceutical Co., Ltd.
Publication of EE9900038A publication Critical patent/EE9900038A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
EEP199900038A 1996-08-01 1997-07-28 Fluori sisaldavad 1,4-diasendatud piperidiini derivaadid EE9900038A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21943696 1996-08-01
JP5397997 1997-02-21
PCT/JP1997/002600 WO1998005641A1 (fr) 1996-08-01 1997-07-28 Derives de piperidine fluores a disubstitution en position 1,4

Publications (1)

Publication Number Publication Date
EE9900038A true EE9900038A (et) 1999-08-16

Family

ID=26394715

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900038A EE9900038A (et) 1996-08-01 1997-07-28 Fluori sisaldavad 1,4-diasendatud piperidiini derivaadid

Country Status (29)

Country Link
US (2) US5948792A (sh)
EP (1) EP0930298B1 (sh)
JP (1) JP3063164B2 (sh)
KR (1) KR20000022214A (sh)
CN (1) CN1226888A (sh)
AR (3) AR008272A1 (sh)
AT (1) ATE229941T1 (sh)
AU (1) AU716050B2 (sh)
BG (1) BG103114A (sh)
BR (1) BR9711108A (sh)
CA (1) CA2261680C (sh)
CO (1) CO4960641A1 (sh)
CZ (1) CZ33199A3 (sh)
DE (1) DE69718026T2 (sh)
EE (1) EE9900038A (sh)
ES (1) ES2188961T3 (sh)
HR (1) HRP970426A2 (sh)
HU (1) HUP9902381A3 (sh)
ID (1) ID17259A (sh)
IL (1) IL127685A0 (sh)
IS (1) IS4960A (sh)
NO (1) NO990472D0 (sh)
NZ (1) NZ333842A (sh)
PE (1) PE92198A1 (sh)
PL (1) PL331431A1 (sh)
SK (1) SK12299A3 (sh)
TR (2) TR200001482T2 (sh)
WO (1) WO1998005641A1 (sh)
YU (1) YU1299A (sh)

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UA73543C2 (uk) 1999-12-07 2005-08-15 Тераванс, Інк. Похідні сечовини, фармацевтична композиція та застосування похідного при приготуванні лікарського засобу для лікування захворювання, яке опосередковується мускариновим рецептором
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US6403584B1 (en) * 2000-06-22 2002-06-11 Merck & Co., Inc. Substituted nipecotyl derivatives as inhibitors of cell adhesion
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ES2266291T3 (es) * 2000-12-28 2007-03-01 Almirall Prodesfarma Ag Nuevos derivados de quinuclidina y composiciones medicinales que los contienen.
DE10111843A1 (de) * 2001-03-13 2002-09-19 Boehringer Ingelheim Pharma Verbindungen zur Behandlung von inflammatorischen Erkrankungen
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JP2006518707A (ja) 2002-12-10 2006-08-17 ランバクシー ラボラトリーズ リミテッド ムスカリン様受容体アンタゴニストとしての3,6−二置換アザビシクロ[3.1.0]ヘキサン誘導体
ES2341240T3 (es) 2002-12-13 2010-06-17 Warner-Lambert Company Llc Ligando alfa-2-delta para tratar los sintomas del tracto urinario inferior.
AU2002347552A1 (en) * 2002-12-23 2004-07-14 Ranbaxy Laboratories Limited 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists
EP1581522B1 (en) 2002-12-23 2008-02-20 Ranbaxy Laboratories Limited Flavaxate derivatives as muscarinic receptor antagonists
US7488748B2 (en) * 2003-01-28 2009-02-10 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
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US7560479B2 (en) 2003-04-10 2009-07-14 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
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Also Published As

Publication number Publication date
BG103114A (en) 1999-11-30
DE69718026D1 (de) 2003-01-30
CN1226888A (zh) 1999-08-25
AU3635197A (en) 1998-02-25
ES2188961T3 (es) 2003-07-01
US6040449A (en) 2000-03-21
EP0930298B1 (en) 2002-12-18
HRP970426A2 (en) 1998-08-31
ATE229941T1 (de) 2003-01-15
IS4960A (is) 1999-01-29
YU1299A (sh) 2002-03-18
IL127685A0 (en) 1999-10-28
TR199900204T2 (xx) 2000-01-21
US5948792A (en) 1999-09-07
HUP9902381A3 (en) 2000-06-28
SK12299A3 (en) 2000-05-16
NO990472L (no) 1999-02-01
EP0930298A1 (en) 1999-07-21
CA2261680C (en) 2005-03-08
PL331431A1 (en) 1999-07-19
JP3063164B2 (ja) 2000-07-12
TR200001482T2 (tr) 2000-11-21
AR016877A2 (es) 2001-08-01
DE69718026T2 (de) 2003-07-10
WO1998005641A1 (fr) 1998-02-12
AU716050B2 (en) 2000-02-17
HUP9902381A2 (hu) 1999-11-29
NZ333842A (en) 2001-05-25
CZ33199A3 (cs) 1999-07-14
CO4960641A1 (es) 2000-09-25
NO990472D0 (no) 1999-02-01
KR20000022214A (ko) 2000-04-25
PE92198A1 (es) 1999-01-09
ID17259A (id) 1997-12-11
CA2261680A1 (en) 1998-02-12
AR017021A1 (es) 2001-08-22
BR9711108A (pt) 1999-08-17
AR008272A1 (es) 1999-12-29
EP0930298A4 (en) 2000-06-07

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