EE200300301A - Asendatud pürasinokinoksaliini derivaadid kui serotoniiniretseptorite agonistid ja antagonistid - Google Patents
Asendatud pürasinokinoksaliini derivaadid kui serotoniiniretseptorite agonistid ja antagonistidInfo
- Publication number
- EE200300301A EE200300301A EEP200300301A EEP200300301A EE200300301A EE 200300301 A EE200300301 A EE 200300301A EE P200300301 A EEP200300301 A EE P200300301A EE P200300301 A EEP200300301 A EE P200300301A EE 200300301 A EE200300301 A EE 200300301A
- Authority
- EE
- Estonia
- Prior art keywords
- antagonists
- disorders
- novel compounds
- agonists
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25676500P | 2000-12-20 | 2000-12-20 | |
PCT/US2001/049374 WO2002059127A2 (en) | 2000-12-20 | 2001-12-19 | Pyrazinoquinoxaline derivatives as serotonin agonists and antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
EE200300301A true EE200300301A (et) | 2003-10-15 |
Family
ID=22973498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200300301A EE200300301A (et) | 2000-12-20 | 2001-12-19 | Asendatud pürasinokinoksaliini derivaadid kui serotoniiniretseptorite agonistid ja antagonistid |
Country Status (23)
Country | Link |
---|---|
US (1) | US6638934B2 (ja) |
EP (1) | EP1345942B9 (ja) |
JP (2) | JP4346307B2 (ja) |
KR (1) | KR20030069192A (ja) |
CN (1) | CN1505631A (ja) |
AT (1) | ATE318819T1 (ja) |
AU (1) | AU2002248216B2 (ja) |
BG (1) | BG107864A (ja) |
BR (1) | BR0116347A (ja) |
CA (1) | CA2431970A1 (ja) |
DE (1) | DE60117617T2 (ja) |
EE (1) | EE200300301A (ja) |
ES (1) | ES2260335T3 (ja) |
HU (1) | HUP0303513A3 (ja) |
IL (1) | IL156201A0 (ja) |
IS (1) | IS6850A (ja) |
MX (1) | MXPA03005437A (ja) |
NO (1) | NO20032795L (ja) |
PL (1) | PL366060A1 (ja) |
RU (1) | RU2003121406A (ja) |
SK (1) | SK7022003A3 (ja) |
WO (1) | WO2002059127A2 (ja) |
ZA (1) | ZA200304303B (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA03005437A (es) * | 2000-12-20 | 2003-09-10 | Bristol Myers Squibb Pharma Co | Derivados substituidos de pirazino quinoxalina como agonistas y antagonistas del receptor de serotonina. |
US7244843B2 (en) | 2003-10-07 | 2007-07-17 | Bristol-Myers Squibb Company | Modulators of serotonin receptors |
GB0417558D0 (en) * | 2004-08-06 | 2004-09-08 | Merck Sharp & Dohme | Novel combination therapy |
US8685924B2 (en) | 2004-08-25 | 2014-04-01 | Takeda Pharmaceutical Company Limited | Preventives/remedies for stress urinary incontinence and method of screening the same |
WO2007132841A1 (ja) | 2006-05-16 | 2007-11-22 | Takeda Pharmaceutical Company Limited | 縮合複素環化合物およびその用途 |
WO2009063992A1 (ja) | 2007-11-15 | 2009-05-22 | Takeda Pharmaceutical Company Limited | 縮合ピリジン誘導体およびその用途 |
US20120253036A1 (en) | 2009-12-11 | 2012-10-04 | Yukinori Nagakura | Agent for treating fibromyalgia |
WO2012030953A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level |
WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
WO2019131902A1 (ja) | 2017-12-27 | 2019-07-04 | 武田薬品工業株式会社 | 腹圧性尿失禁および便失禁の治療薬 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4115577A (en) | 1972-06-19 | 1978-09-19 | Endo Laboratories, Inc. | Pyridopyrrolobenzheterocycles |
US3914421A (en) | 1972-06-19 | 1975-10-21 | Endo Lab | Pyridopyrrolobenzheterocycles for combatting depression |
US4013652A (en) | 1972-06-19 | 1977-03-22 | Endo Laboratories, Inc. | Pyridopyrrolobenzoxazine |
US4238607A (en) | 1972-06-19 | 1980-12-09 | Endo Laboratories Inc. | Pyridopyrrolo benzheterocycles |
US4183936A (en) | 1972-06-19 | 1980-01-15 | Endo Laboratories, Inc. | Pyridopyrrolobenzheterocycles |
US4219550A (en) | 1978-11-09 | 1980-08-26 | E. I. Du Pont De Nemours And Company | Cis- and trans- octahydropyridopyrrolobenzheterocycles |
HUT61548A (en) * | 1990-08-27 | 1993-01-28 | Sandoz Ag | Process for producing indolonaphthyridine derivatives and pharmaceutical compositions comprising such compounds |
JP2002532504A (ja) * | 1998-12-17 | 2002-10-02 | アメリカン・ホーム・プロダクツ・コーポレイション | 5−ht2c作動薬である2,3,4,4a−テトラヒドロ−1h−ピラジノ(1,2−a)キノキサリン−5(6h)−オン誘導体 |
MXPA03005437A (es) * | 2000-12-20 | 2003-09-10 | Bristol Myers Squibb Pharma Co | Derivados substituidos de pirazino quinoxalina como agonistas y antagonistas del receptor de serotonina. |
-
2001
- 2001-12-19 MX MXPA03005437A patent/MXPA03005437A/es unknown
- 2001-12-19 EP EP01997097A patent/EP1345942B9/en not_active Expired - Lifetime
- 2001-12-19 KR KR10-2003-7008273A patent/KR20030069192A/ko not_active Application Discontinuation
- 2001-12-19 BR BR0116347-7A patent/BR0116347A/pt not_active Application Discontinuation
- 2001-12-19 ES ES01997097T patent/ES2260335T3/es not_active Expired - Lifetime
- 2001-12-19 RU RU2003121406/04A patent/RU2003121406A/ru not_active Application Discontinuation
- 2001-12-19 CA CA002431970A patent/CA2431970A1/en not_active Abandoned
- 2001-12-19 JP JP2002559429A patent/JP4346307B2/ja not_active Expired - Fee Related
- 2001-12-19 AU AU2002248216A patent/AU2002248216B2/en not_active Ceased
- 2001-12-19 EE EEP200300301A patent/EE200300301A/xx unknown
- 2001-12-19 DE DE60117617T patent/DE60117617T2/de not_active Expired - Lifetime
- 2001-12-19 IL IL15620101A patent/IL156201A0/xx unknown
- 2001-12-19 WO PCT/US2001/049374 patent/WO2002059127A2/en active IP Right Grant
- 2001-12-19 US US10/026,404 patent/US6638934B2/en not_active Expired - Lifetime
- 2001-12-19 AT AT01997097T patent/ATE318819T1/de active
- 2001-12-19 HU HU0303513A patent/HUP0303513A3/hu not_active Application Discontinuation
- 2001-12-19 PL PL01366060A patent/PL366060A1/xx not_active Application Discontinuation
- 2001-12-19 SK SK702-2003A patent/SK7022003A3/sk unknown
- 2001-12-19 CN CNA01822704XA patent/CN1505631A/zh active Pending
-
2003
- 2003-05-30 BG BG107864A patent/BG107864A/bg unknown
- 2003-06-02 ZA ZA200304303A patent/ZA200304303B/en unknown
- 2003-06-18 IS IS6850A patent/IS6850A/is unknown
- 2003-06-19 NO NO20032795A patent/NO20032795L/no not_active Application Discontinuation
-
2009
- 2009-05-11 JP JP2009114360A patent/JP5117440B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2002059127A3 (en) | 2002-10-03 |
KR20030069192A (ko) | 2003-08-25 |
EP1345942B1 (en) | 2006-03-01 |
AU2002248216B2 (en) | 2007-03-01 |
RU2003121406A (ru) | 2004-12-27 |
CN1505631A (zh) | 2004-06-16 |
US6638934B2 (en) | 2003-10-28 |
EP1345942A2 (en) | 2003-09-24 |
NO20032795D0 (no) | 2003-06-19 |
BR0116347A (pt) | 2004-07-06 |
MXPA03005437A (es) | 2003-09-10 |
EP1345942B9 (en) | 2006-11-15 |
DE60117617D1 (de) | 2006-04-27 |
CA2431970A1 (en) | 2002-08-01 |
IS6850A (is) | 2003-06-18 |
HUP0303513A3 (en) | 2005-12-28 |
IL156201A0 (en) | 2003-12-23 |
ZA200304303B (en) | 2004-09-02 |
NO20032795L (no) | 2003-08-04 |
PL366060A1 (en) | 2005-01-24 |
JP2004524298A (ja) | 2004-08-12 |
JP5117440B2 (ja) | 2013-01-16 |
BG107864A (bg) | 2004-03-31 |
WO2002059127A2 (en) | 2002-08-01 |
JP4346307B2 (ja) | 2009-10-21 |
SK7022003A3 (en) | 2004-08-03 |
HUP0303513A2 (hu) | 2004-01-28 |
JP2009215304A (ja) | 2009-09-24 |
ES2260335T3 (es) | 2006-11-01 |
DE60117617T2 (de) | 2007-01-25 |
US20020177596A1 (en) | 2002-11-28 |
ATE318819T1 (de) | 2006-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EE200300303A (et) | Asendatud pürrolokinoliinid ja püridokinoliinid kui serotoniini agonistid ja antagonistid | |
MXPA03005438A (es) | Pirioindoles substituidos como agonistas y antagonistas de serotonina. | |
MXPA01012914A (es) | Gama-carbolinas fundidas de heterociclo substituido. | |
ATE509929T1 (de) | Substituierte tricyclische gamma-carbolineals serotonin-rezeptor-agonisten und antagonisten | |
HK1098460A1 (en) | Fused hetrocyclic compounds and their use as metabotropic receptor antagonists for the treatment of gastrointestinal disorders | |
EE200300301A (et) | Asendatud pürasinokinoksaliini derivaadid kui serotoniiniretseptorite agonistid ja antagonistid | |
CA2354606A1 (en) | Azabicycloalkane derivatives and therapeutic uses thereof | |
HUP0303316A2 (hu) | Aril- és amino-aril-szubsztituált szerotoninreceptor agonista és antagonista ligandumok és ezeket tartalmazó gyógyszerkészítmények | |
GB0311349D0 (en) | Therapeutic agents, compositions, preparations and uses |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
HB1A | Correction of owner name or address |