EE200000768A - 2-(puriin-9-üül)tetrahüdrofuraan-3,4-diooli derivaadid - Google Patents

2-(puriin-9-üül)tetrahüdrofuraan-3,4-diooli derivaadid

Info

Publication number
EE200000768A
EE200000768A EEP200000768A EEP200000768A EE200000768A EE 200000768 A EE200000768 A EE 200000768A EE P200000768 A EEP200000768 A EE P200000768A EE P200000768 A EEP200000768 A EE P200000768A EE 200000768 A EE200000768 A EE 200000768A
Authority
EE
Estonia
Prior art keywords
purin
tetrahydrofuran
diol derivatives
diol
derivatives
Prior art date
Application number
EEP200000768A
Other languages
English (en)
Estonian (et)
Inventor
George Allen David
Peter Charles Cousins Richard
Victoria Geden Joanna
Elaine Keeling Suzanne
Judith Redgrave Alison
Davis Roper Thomas Iv
Chan Chuen
Cox Brian
Hobbs Heather
Xie Shiping
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9813538.7A external-priority patent/GB9813538D0/en
Priority claimed from GBGB9909482.3A external-priority patent/GB9909482D0/en
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of EE200000768A publication Critical patent/EE200000768A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/06—Heterocyclic radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
EEP200000768A 1998-06-23 1999-06-23 2-(puriin-9-üül)tetrahüdrofuraan-3,4-diooli derivaadid EE200000768A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9813538.7A GB9813538D0 (en) 1998-06-23 1998-06-23 Chemical compounds
GBGB9909482.3A GB9909482D0 (en) 1999-04-23 1999-04-23 2-(Purin-9-yl)-tetahydrofuran-3,4-diol derivatives
PCT/EP1999/004269 WO1999067265A1 (en) 1998-06-23 1999-06-23 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives

Publications (1)

Publication Number Publication Date
EE200000768A true EE200000768A (et) 2002-04-15

Family

ID=26313917

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000768A EE200000768A (et) 1998-06-23 1999-06-23 2-(puriin-9-üül)tetrahüdrofuraan-3,4-diooli derivaadid

Country Status (27)

Country Link
US (1) US6495528B1 (pt)
EP (1) EP1090022B1 (pt)
JP (1) JP3933870B2 (pt)
KR (1) KR20010071591A (pt)
CN (1) CN1313861A (pt)
AP (1) AP2000002016A0 (pt)
AT (1) ATE246701T1 (pt)
AU (1) AU750462B2 (pt)
BR (1) BR9911482A (pt)
CA (1) CA2335809A1 (pt)
CZ (1) CZ20004868A3 (pt)
DE (1) DE69910213T2 (pt)
EA (1) EA200001224A1 (pt)
EE (1) EE200000768A (pt)
ES (1) ES2204139T3 (pt)
HR (1) HRP20000894A2 (pt)
HU (1) HUP0103025A3 (pt)
ID (1) ID29609A (pt)
IL (1) IL140396A0 (pt)
IS (1) IS5779A (pt)
NO (1) NO20006548L (pt)
NZ (1) NZ509030A (pt)
PL (1) PL345062A1 (pt)
SK (1) SK19542000A3 (pt)
TR (1) TR200100410T2 (pt)
WO (1) WO1999067265A1 (pt)
YU (1) YU81100A (pt)

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US7427606B2 (en) 1999-02-01 2008-09-23 University Of Virginia Patent Foundation Method to reduce inflammatory response in transplanted tissue
US6232297B1 (en) 1999-02-01 2001-05-15 University Of Virginia Patent Foundation Methods and compositions for treating inflammatory response
US7378400B2 (en) 1999-02-01 2008-05-27 University Of Virginia Patent Foundation Method to reduce an inflammatory response from arthritis
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US7576069B2 (en) 2004-08-02 2009-08-18 University Of Virginia Patent Foundation 2-polycyclic propynyl adenosine analogs having A2A agonist activity
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
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GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
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JP5373599B2 (ja) 2006-04-21 2013-12-18 ノバルティス アーゲー アデノシンａ２ａ受容体アゴニストとして使用するためのプリン誘導体
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EP1903044A1 (en) 2006-09-14 2008-03-26 Novartis AG Adenosine Derivatives as A2A Receptor Agonists
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Also Published As

Publication number Publication date
AP2000002016A0 (en) 2000-12-31
YU81100A (sh) 2003-10-31
TR200100410T2 (tr) 2001-06-21
DE69910213D1 (de) 2003-09-11
US6495528B1 (en) 2002-12-17
HUP0103025A2 (hu) 2001-12-28
CN1313861A (zh) 2001-09-19
HUP0103025A3 (en) 2002-04-29
EP1090022B1 (en) 2003-08-06
JP3933870B2 (ja) 2007-06-20
JP2002518512A (ja) 2002-06-25
IL140396A0 (en) 2002-02-10
PL345062A1 (en) 2001-11-19
EA200001224A1 (ru) 2001-08-27
DE69910213T2 (de) 2004-07-01
BR9911482A (pt) 2002-01-22
KR20010071591A (ko) 2001-07-28
ATE246701T1 (de) 2003-08-15
ES2204139T3 (es) 2004-04-16
CA2335809A1 (en) 1999-12-29
ID29609A (id) 2001-09-06
HRP20000894A2 (en) 2001-12-31
NO20006548L (no) 2001-02-22
NZ509030A (en) 2003-07-25
CZ20004868A3 (cs) 2001-08-15
EP1090022A1 (en) 2001-04-11
AU4774499A (en) 2000-01-10
NO20006548D0 (no) 2000-12-21
SK19542000A3 (sk) 2001-09-11
IS5779A (is) 2000-12-19
AU750462B2 (en) 2002-07-18
WO1999067265A1 (en) 1999-12-29

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