EE03155B1 - Selektiivsed aromataasi pärssivad ühendid ja nende kasutamine - Google Patents

Selektiivsed aromataasi pärssivad ühendid ja nende kasutamine

Info

Publication number
EE03155B1
EE03155B1 EE9400434A EE9400434A EE03155B1 EE 03155 B1 EE03155 B1 EE 03155B1 EE 9400434 A EE9400434 A EE 9400434A EE 9400434 A EE9400434 A EE 9400434A EE 03155 B1 EE03155 B1 EE 03155B1
Authority
EE
Estonia
Prior art keywords
pct
choh
date
compounds
sec
Prior art date
Application number
EE9400434A
Other languages
English (en)
Estonian (et)
Inventor
Johannes Karjalainen Arto
Marketta Kalapudas Arja
Olavi Pelkonen Reino
Marja Laine Aire
Arvo Sakari Lammintausta Risto
Sakari Salonen Jarmo
S�dervall Marja-Liisa
Original Assignee
Orion-Yhtym Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion-Yhtym Oy filed Critical Orion-Yhtym Oy
Publication of EE03155B1 publication Critical patent/EE03155B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
EE9400434A 1992-12-16 1994-11-22 Selektiivsed aromataasi pärssivad ühendid ja nende kasutamine EE03155B1 (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9226209A GB2273704B (en) 1992-12-16 1992-12-16 Triazolyl diaryl selective aromatase inhibiting compounds

Publications (1)

Publication Number Publication Date
EE03155B1 true EE03155B1 (et) 1999-02-15

Family

ID=10726697

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9400434A EE03155B1 (et) 1992-12-16 1994-11-22 Selektiivsed aromataasi pärssivad ühendid ja nende kasutamine

Country Status (31)

Country Link
US (2) US5703109A (sk)
EP (1) EP0674626B1 (sk)
JP (1) JP3186771B2 (sk)
KR (1) KR100347639B1 (sk)
CN (1) CN1056835C (sk)
AT (1) ATE194833T1 (sk)
AU (1) AU682332B2 (sk)
BG (1) BG62930B1 (sk)
CA (1) CA2150904A1 (sk)
CZ (1) CZ283043B6 (sk)
DE (1) DE69329072T2 (sk)
DK (1) DK0674626T3 (sk)
EE (1) EE03155B1 (sk)
ES (1) ES2148312T3 (sk)
FI (1) FI952867A (sk)
GB (1) GB2273704B (sk)
GR (1) GR3034618T3 (sk)
HR (1) HRP931494B1 (sk)
IL (1) IL107714A (sk)
LT (1) LT3151B (sk)
NO (1) NO310237B1 (sk)
NZ (1) NZ258588A (sk)
PL (1) PL176413B1 (sk)
PT (1) PT674626E (sk)
RO (1) RO113986B1 (sk)
RU (1) RU2131418C1 (sk)
SI (1) SI9300663B (sk)
SK (1) SK281667B6 (sk)
TW (1) TW327169B (sk)
WO (1) WO1994013645A1 (sk)
ZA (1) ZA938717B (sk)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063930A (en) * 1996-04-03 2000-05-16 Merck & Co., Inc. Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6080870A (en) * 1996-04-03 2000-06-27 Merck & Co., Inc. Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
EP0891334A1 (en) * 1996-04-03 1999-01-20 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5972921A (en) * 1997-12-12 1999-10-26 Hormos Medical Oy Ltd. Use of an aromatase inhibitor in the treatment of decreased androgen to estrogen ratio and detrusor urethral sphincter dyssynergia in men
WO2002009703A1 (en) * 2000-07-10 2002-02-07 Hormos Medical Corporation Method for treating cryptorchidism
FI20010905A0 (fi) * 2001-05-02 2001-05-02 Vetcare Oy Uusi eläinlääke
EP1456184A1 (en) * 2001-12-11 2004-09-15 Emory University Bis(cyanophenyl)methyl-triazole for use in prevention of breast cancer
US6737433B1 (en) * 2002-12-16 2004-05-18 Laboratoire Theramex 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors and pharmaceutical compositions containing them
JP2004196795A (ja) * 2002-12-16 2004-07-15 Wyeth 外部寄生虫駆除剤としてのｎ−フェニル−３−シクロプロピルピラゾール−４−カルボニトリル
US7345073B2 (en) 2003-02-07 2008-03-18 Hormos Medical Ltd. Method for treating cryptorchidism
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
CN1890221B (zh) * 2003-12-15 2014-07-16 沙拉麦斯实验公司 1-n-苯基-氨基-1h-咪唑衍生物和含有它们的医药组合物
RU2480207C2 (ru) * 2006-05-22 2013-04-27 Хормос Медикал Лтд. Способ лечения хронического абактериального простатита селективными модуляторами рецепторов эстрогена или ингибиторами ароматазы
GB0914767D0 (en) * 2009-08-24 2009-09-30 Sterix Ltd Compound
CN102884072A (zh) 2010-04-08 2013-01-16 爱默蕾大学 被取代的雄甾-4-烯二酮
WO2011147814A1 (de) * 2010-05-27 2011-12-01 Bayer Cropscience Ag Heterocyclische alkanolderivate als fungizide
KR101583521B1 (ko) 2015-07-31 2016-01-08 (주) 엘림비엠에스 내오염, 내마모 성능과 시공 작업성 및 광도 성능이 개선된 피브이씨 타일 바닥의 코팅방법
US11026519B2 (en) 2018-04-19 2021-06-08 Wonderland Switzerland Ag Child carrier

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1580535A (en) * 1976-08-27 1980-12-03 Ici Ltd Substituted ketones and their use as herbicides
US4978672A (en) 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
US4937250A (en) 1988-03-07 1990-06-26 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US5071861A (en) 1986-03-07 1991-12-10 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US5112845A (en) * 1986-03-07 1992-05-12 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US4749713A (en) * 1986-03-07 1988-06-07 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
AU627559B2 (en) * 1989-03-30 1992-08-27 Farmos-Yhtyma Oy Novel aromatase inhibiting 4(5)-imidazoles
ATE135000T1 (de) * 1989-07-14 1996-03-15 Ciba Geigy Ag Substituierte benzonitrile
DE4039559A1 (de) * 1990-12-07 1992-06-11 Schering Ag Funktionalisierte vinylazole, verfahren zu deren herstellung, pharmazeutische praeparate die diese vinylazole enthalten sowie deren verwendung zur herstellung von arzneimitteln
GB9125924D0 (en) * 1991-06-18 1992-02-05 Orion Yhtymae Oy Stereoisomers of an imidazole derivative

Also Published As

Publication number Publication date
SK77895A3 (en) 1995-12-06
SK281667B6 (sk) 2001-06-11
JP3186771B2 (ja) 2001-07-11
EP0674626B1 (en) 2000-07-19
GR3034618T3 (en) 2001-01-31
IL107714A (en) 2003-07-31
NO952365L (no) 1995-06-15
KR950704263A (ko) 1995-11-17
JPH08504424A (ja) 1996-05-14
DK0674626T3 (da) 2000-11-13
LT3151B (en) 1995-01-31
NO952365D0 (no) 1995-06-15
SI9300663B (sl) 2002-02-28
NZ258588A (en) 1996-11-26
HRP931494B1 (en) 2001-06-30
AU5652394A (en) 1994-07-04
DE69329072D1 (de) 2000-08-24
EP0674626A1 (en) 1995-10-04
TW327169B (en) 1998-02-21
FI952867A0 (fi) 1995-06-09
US5962495A (en) 1999-10-05
SI9300663A (en) 1994-09-30
US5703109A (en) 1997-12-30
CN1056835C (zh) 2000-09-27
CA2150904A1 (en) 1994-06-23
LTIP1524A (en) 1994-07-15
KR100347639B1 (ko) 2002-11-29
RO113986B1 (ro) 1998-12-30
BG99699A (bg) 1996-04-30
GB2273704B (en) 1997-01-22
PT674626E (pt) 2000-11-30
ES2148312T3 (es) 2000-10-16
AU682332B2 (en) 1997-10-02
ATE194833T1 (de) 2000-08-15
BG62930B1 (bg) 2000-11-30
DE69329072T2 (de) 2000-12-21
CN1093357A (zh) 1994-10-12
CZ283043B6 (cs) 1997-12-17
PL176413B1 (pl) 1999-05-31
FI952867A (fi) 1995-06-09
NO310237B1 (no) 2001-06-11
IL107714A0 (en) 1994-02-27
GB9226209D0 (en) 1993-02-10
CZ153295A3 (en) 1995-11-15
RU2131418C1 (ru) 1999-06-10
GB2273704A (en) 1994-06-29
ZA938717B (en) 1994-06-30
PL309350A1 (en) 1995-10-02
HRP931494A2 (en) 1996-08-31
WO1994013645A1 (en) 1994-06-23
RU95114360A (ru) 1997-06-10

Similar Documents

Publication Publication Date Title
EE03155B1 (et) Selektiivsed aromataasi pärssivad ühendid ja nende kasutamine
ES2169355T3 (es) Derivados de 4-anilinoquinazolina.
DE60025848D1 (en) Pyrimidin-derivate als selective inhibitoren von cox-2
RU94046463A (ru) Антиандрогенное соединение, предшественник лекарственного средства, фармацевтические композиции, способ лечения или предотвращения заболеваний
NO983724D0 (no) 17-<beta>-syklopropyl (amino/oksi)-4-aza-steroider som aktive inhibitorer av testosteron-5-<alfa>-reduktase og C17-20-lylase
GR3025050T3 (en) Etoposide derivatives, process for their preparation, their use as a drug and in the preparation of a drug for treating cancer.
NO913712L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazol-derivater.
FR2804957B1 (fr) Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

MM4A Lapsed by not paying the annual fees

Effective date: 20031122