ECSP109851A - Sales de amina de un antagonista de crth2 - Google Patents

Sales de amina de un antagonista de crth2

Info

Publication number
ECSP109851A
ECSP109851A EC2010009851A ECSP109851A ECSP109851A EC SP109851 A ECSP109851 A EC SP109851A EC 2010009851 A EC2010009851 A EC 2010009851A EC SP109851 A ECSP109851 A EC SP109851A EC SP109851 A ECSP109851 A EC SP109851A
Authority
EC
Ecuador
Prior art keywords
salts
amina
crth2 antagonist
crth2
benzamido
Prior art date
Application number
EC2010009851A
Other languages
English (en)
Inventor
Tai Wei Ly
Original Assignee
Actimis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39731477&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP109851(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Actimis Pharmaceuticals Inc filed Critical Actimis Pharmaceuticals Inc
Publication of ECSP109851A publication Critical patent/ECSP109851A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se proveen sales de amina de ácido [(4,6-bis(dimetilamino)-2-(4-(4-(trifluorometil) benzamido) bencil) pirimidin-5-il] acético, procesos para su preparación, composiciones farmacéuticas, que los contienen, y su uso para tratar, prevenir, o aliviar uno o más síntomas de un trastorno o enfermedad mediado por CRTH2.
EC2010009851A 2007-06-21 2010-01-06 Sales de amina de un antagonista de crth2 ECSP109851A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93673607P 2007-06-21 2007-06-21

Publications (1)

Publication Number Publication Date
ECSP109851A true ECSP109851A (es) 2010-03-31

Family

ID=39731477

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010009851A ECSP109851A (es) 2007-06-21 2010-01-06 Sales de amina de un antagonista de crth2

Country Status (23)

Country Link
US (1) US8278310B2 (es)
EP (1) EP2176240A1 (es)
JP (1) JP6006914B2 (es)
KR (1) KR20100039350A (es)
CN (4) CN102898381A (es)
AR (1) AR067118A1 (es)
BR (1) BRPI0812597A2 (es)
CA (1) CA2690436A1 (es)
CL (1) CL2008001817A1 (es)
CO (1) CO6251286A2 (es)
EC (1) ECSP109851A (es)
HK (1) HK1144940A1 (es)
IL (1) IL202755A0 (es)
MA (1) MA31536B1 (es)
MX (1) MX2009013813A (es)
MY (1) MY149005A (es)
NZ (1) NZ581856A (es)
RU (1) RU2468013C2 (es)
TN (1) TN2009000517A1 (es)
TW (1) TWI419693B (es)
UA (1) UA101326C2 (es)
WO (1) WO2008156781A1 (es)
ZA (1) ZA200909110B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1471057E (pt) 2003-04-25 2006-05-31 Actimis Pharmaceuticals Inc Derivados de acido pirimidinilacetico uteis para o tratamento de doencas mediadas por crth2
CA2735722A1 (en) * 2008-09-02 2010-03-11 Actimis Pharmaceuticals, Inc. Isotopically enriched pyrimidin-5-yl acetic acid derivatives as crth2 antagonists
WO2010089391A1 (en) * 2009-02-09 2010-08-12 Boehringer Ingelheim International Gmbh New pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
EP2451787B1 (en) 2009-07-06 2013-04-24 Boehringer Ingelheim International GmbH Polymorph of [4,6-bis(dimethylamino)-2-(4-{[4-(trifluoromethyl)benzoyl]amino}benzyl)pyrimidin-5-yl]
CA2781610A1 (en) * 2009-11-24 2011-06-03 Boehringer Ingelheim International Gmbh Process for preparing a polymorph of the choline salt of a pyrimidin-5-yl acetic acid derivative
JP2013512239A (ja) 2009-11-24 2013-04-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ピリミジン−５−イル酢酸誘導体の新規な塩の形態
JP2013535456A (ja) * 2010-07-28 2013-09-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器系及び炎症性疾患の治療用医薬組成物
EP2598145A1 (en) 2010-07-28 2013-06-05 Boehringer Ingelheim International GmbH Pharmaceutical composition for treatment of respiratory and inflammatory diseases
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
EA026456B1 (ru) 2011-12-16 2017-04-28 Атопикс Терапьютикс Лимитед Фармацевтическая композиция на основе антагониста crth2 и ингибитора протонного насоса для лечения эозинофильного эзофагита
EP3108460A1 (en) 2014-02-18 2016-12-28 Bekey A/S Controlling access to a location
RU2019128534A (ru) 2017-02-15 2021-03-16 Наньян Текнолоджикал Юниверсити Химические соединения для лечения туберкулеза

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1280522E (pt) * 2000-04-26 2005-02-28 Warner Lambert Co Combinacao de eteres carboxialquilicos com anti-hipertensores e a utilizacao farmaceutica
US7078690B2 (en) * 2002-02-04 2006-07-18 Applied Materials, Israel, Ltd. Monitoring of contact hole production
PT1471057E (pt) * 2003-04-25 2006-05-31 Actimis Pharmaceuticals Inc Derivados de acido pirimidinilacetico uteis para o tratamento de doencas mediadas por crth2
SE0301569D0 (sv) * 2003-05-27 2003-05-27 Astrazeneca Ab Novel compounds
WO2006109836A1 (en) * 2005-04-07 2006-10-19 Teijin Pharma Limited Crystal of aminopyrrolidine derivative and prodcution method thereof
JP2010530425A (ja) * 2007-06-21 2010-09-09 アクチミス ファーマシューティカルズ インコーポレーテッド Ｃｒｔｈ２アンタゴニストの粒子
CA2735722A1 (en) * 2008-09-02 2010-03-11 Actimis Pharmaceuticals, Inc. Isotopically enriched pyrimidin-5-yl acetic acid derivatives as crth2 antagonists

Also Published As

Publication number Publication date
CN101772489A (zh) 2010-07-07
CN102875478A (zh) 2013-01-16
RU2010101795A (ru) 2011-07-27
AU2008266854A1 (en) 2008-12-24
AR067118A1 (es) 2009-09-30
CN102898380A (zh) 2013-01-30
MX2009013813A (es) 2010-02-03
JP2010530426A (ja) 2010-09-09
CA2690436A1 (en) 2008-12-24
UA101326C2 (en) 2013-03-25
ZA200909110B (en) 2011-03-30
US20110034482A1 (en) 2011-02-10
HK1144940A1 (en) 2011-03-18
CL2008001817A1 (es) 2009-03-13
TWI419693B (zh) 2013-12-21
CN102898381A (zh) 2013-01-30
BRPI0812597A2 (pt) 2015-02-18
TW200911261A (en) 2009-03-16
IL202755A0 (en) 2010-06-30
JP6006914B2 (ja) 2016-10-12
MY149005A (en) 2013-06-28
CN101772489B (zh) 2013-02-20
NZ581856A (en) 2011-05-27
WO2008156781A1 (en) 2008-12-24
MA31536B1 (fr) 2010-07-01
EP2176240A1 (en) 2010-04-21
RU2468013C2 (ru) 2012-11-27
US8278310B2 (en) 2012-10-02
CO6251286A2 (es) 2011-02-21
TN2009000517A1 (en) 2011-03-31
KR20100039350A (ko) 2010-04-15

Similar Documents

Publication Publication Date Title
ECSP109851A (es) Sales de amina de un antagonista de crth2
ECSP109890A (es) Particulas de un antagonista de crth2
UY32203A (es) Amino pirimidinas y su uso en terapia
UY32351A (es) Compuestos de pirimidinil indol para uso como inhibidores de atr
CR11857A (es) Compuestos pirazolicos 436
NI201200184A (es) Morfolinopirimidinas y su uso en terapia
ECSP099750A (es) Imidazoquinolinas con propiedades inmunomoduladoras
ECSP109917A (es) Nuevos derivados de ácido azabifenilaminobenzoico
UY30141A1 (es) Nuevas isoindolonas potenciadoras de receptores metabotropicos de glutamato
CO6440584A2 (es) Compuestos diamida que tienen actividad como antagonistas de los receptores muscarínicos y como agonistas de los receptores adrenérgicos beta 2
DOP2010000134A (es) Algunos derivados de 2-pirazinona como inhibidores de elastasa de los neutrofilos
UY28765A1 (es) Compuestos de piperazina acetilínica y su uso como antagonistas del receptor de glutamato metabotrópico
BRPI0817843B8 (pt) inibidores da quinase c-fms, composição farmacêutica que os compreende e processo para a fabricação da dita composição
NO20074567L (no) Glucagonreseptorantagoniser, fremstilling og terapeutisk anvendelse
BRPI0707704A8 (pt) derivados de antranilamida / 2-amino-heteroareno carboxamida
UY32848A (es) Compuestos heterocíclicos de oxima
CR10963A (es) Compuestos de 2-amino pirimidina
BRPI0815360A8 (pt) Composto derivado de 4-pirimidinossulfamida, composição farmacêutica que o contem, uso e processo para a preparação do composto
BR112013008211A8 (pt) Cocristais e sais de inibidores de ccr3, seu uso e composição que os compreende
BRPI0511999A (pt) compostos como antagonistas de ccr5
BRPI0918517B8 (pt) composto, composição farmacêutica, e, uso de um composto
AR058047A1 (es) Administracion de inhibidores de dipeptidil peptidasa
BRPI0821611A8 (pt) Derivado de 3-carboxipropil-aminotetralina e compostos relacionados como antagonistas do receptor opióide mu
AR082659A1 (es) Composiciones farmaceuticas para el tratamiento de enfermedades respiratorias e inflamatorias
UY29824A1 (es) Preparación de derivados de quinazolinas o sales de los mismos, intermedios utilizados en su preparación y preparación de dichos derivados utilizando esos intermedios