ECSP077232A - Derivados de triazolopridinilsulfanilo como inhibidores de quinasa map p38 - Google Patents

Derivados de triazolopridinilsulfanilo como inhibidores de quinasa map p38

Info

Publication number
ECSP077232A
ECSP077232A EC2007007232A ECSP077232A ECSP077232A EC SP077232 A ECSP077232 A EC SP077232A EC 2007007232 A EC2007007232 A EC 2007007232A EC SP077232 A ECSP077232 A EC SP077232A EC SP077232 A ECSP077232 A EC SP077232A
Authority
EC
Ecuador
Prior art keywords
triazolopridinilsulfanilo
quinasa
inhibitors
map
derivatives
Prior art date
Application number
EC2007007232A
Other languages
English (en)
Inventor
John Paul Mathias
Russell Andrew Lewthwaite
David Simon Millan
Christopher Phillips
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0418015A external-priority patent/GB0418015D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of ECSP077232A publication Critical patent/ECSP077232A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Virology (AREA)
  • Neurology (AREA)
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  • Immunology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
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  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
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Abstract

Un compuesto de fórmula (I), o un sal y/o solvato (incluyendo un hidrato) farmacéuticamente aceptable del mismo; (consta gráfico) y el uso de compuestos de fórmula (I) en el tratamiento de una enfermedad, trastorno o afección mediada por TNF, o una enfermedad, trastorno o afección mediada por p38, en particular las enfermedades alérgicas y no alérgicas de las vías respiratorias, más particularmente enfermedades obstructivas o inflamatorias de las vías respiratorias, preferiblemente la enfermedad pulmonar obstructiva crónica.
EC2007007232A 2004-08-12 2007-02-09 Derivados de triazolopridinilsulfanilo como inhibidores de quinasa map p38 ECSP077232A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0418015A GB0418015D0 (en) 2004-08-12 2004-08-12 New compounds
US69155905P 2005-06-17 2005-06-17

Publications (1)

Publication Number Publication Date
ECSP077232A true ECSP077232A (es) 2007-03-29

Family

ID=35783420

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2007007232A ECSP077232A (es) 2004-08-12 2007-02-09 Derivados de triazolopridinilsulfanilo como inhibidores de quinasa map p38

Country Status (34)

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US (2) US7511057B2 (es)
EP (1) EP1778686B9 (es)
JP (1) JP4084836B2 (es)
AP (1) AP2326A (es)
AR (1) AR050692A1 (es)
AT (1) ATE412652T1 (es)
AU (1) AU2005273612B2 (es)
BR (1) BRPI0514255A (es)
CA (1) CA2576297C (es)
CR (1) CR8918A (es)
CU (1) CU23497A3 (es)
CY (1) CY1108788T1 (es)
DE (1) DE602005010714D1 (es)
DK (1) DK1778686T3 (es)
EA (1) EA012119B1 (es)
EC (1) ECSP077232A (es)
ES (1) ES2314690T3 (es)
GE (1) GEP20104973B (es)
GT (1) GT200500218A (es)
HN (1) HN2005000418A (es)
HR (1) HRP20080608T3 (es)
IL (1) IL181047A (es)
MA (1) MA28798B1 (es)
MX (1) MX2007001759A (es)
MY (1) MY140021A (es)
NL (1) NL1029726C2 (es)
NO (1) NO339320B1 (es)
NZ (1) NZ552868A (es)
PL (1) PL1778686T3 (es)
PT (1) PT1778686E (es)
SI (1) SI1778686T1 (es)
SV (1) SV2006002193A (es)
TN (1) TNSN07050A1 (es)
WO (1) WO2006018718A2 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572807B2 (en) * 2005-06-09 2009-08-11 Bristol-Myers Squibb Company Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
US7579360B2 (en) * 2005-06-09 2009-08-25 Bristol-Myers Squibb Company Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
EP1984363A1 (en) * 2006-02-09 2008-10-29 Pfizer Limited Triazolopyridine compounds
JP5244369B2 (ja) * 2006-11-10 2013-07-24 富士フイルム株式会社 ５−アミノピラゾール誘導体の製造方法、アゾ色素
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