CY1108788T1 - Τριαζολοπυριδινυλσουλφανυλ παραγωγα ως αναστολεις ρ38 map κινασης - Google Patents

Τριαζολοπυριδινυλσουλφανυλ παραγωγα ως αναστολεις ρ38 map κινασης

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Publication number
CY1108788T1
CY1108788T1 CY20081101380T CY081101380T CY1108788T1 CY 1108788 T1 CY1108788 T1 CY 1108788T1 CY 20081101380 T CY20081101380 T CY 20081101380T CY 081101380 T CY081101380 T CY 081101380T CY 1108788 T1 CY1108788 T1 CY 1108788T1
Authority
CY
Cyprus
Prior art keywords
kinase inhibitors
map kinase
formula
disorder
compound
Prior art date
Application number
CY20081101380T
Other languages
English (en)
Inventor
John Paul Mathias
David Simon Millan
Russell Andrew Lewthwaite
Christopher Phillips
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0418015A external-priority patent/GB0418015D0/en
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of CY1108788T1 publication Critical patent/CY1108788T1/el

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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Abstract

Μία ένωση του τύπου (I) ή φαρμακευτικώς αποδεκτό άλας ή/και διαλύτωμα (συμπεριλαμβανομένου υδρίτη) αυτής. Ο τύπος (I) και η χρήση μιας ένωσης του τύπου (I) στη θεραπεία προκαλούμενης από TNF ασθένειας, διαταραχής ή κατάστασης ή μιας προκαλούμενης από p38 ασθένειας, διαταραχής ή κατάστασης, συγκεκριμένα τις αλλεργικές και μη-αλλεργικές ασθένειες των αεροδών, ειδικότερα αποφρακτικές ή φλεγμονώδεις ασθένειες των αεροδών, κατά προτίμηση χρόνιας αποφρακτικής πνευμονοπάθειας.
CY20081101380T 2004-08-12 2008-12-01 Τριαζολοπυριδινυλσουλφανυλ παραγωγα ως αναστολεις ρ38 map κινασης CY1108788T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0418015A GB0418015D0 (en) 2004-08-12 2004-08-12 New compounds
US69155905P 2005-06-17 2005-06-17
EP05772546A EP1778686B9 (en) 2004-08-12 2005-08-09 Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors

Publications (1)

Publication Number Publication Date
CY1108788T1 true CY1108788T1 (el) 2014-07-02

Family

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CY20081101380T CY1108788T1 (el) 2004-08-12 2008-12-01 Τριαζολοπυριδινυλσουλφανυλ παραγωγα ως αναστολεις ρ38 map κινασης

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US (2) US7511057B2 (el)
EP (1) EP1778686B9 (el)
JP (1) JP4084836B2 (el)
AP (1) AP2326A (el)
AR (1) AR050692A1 (el)
AT (1) ATE412652T1 (el)
AU (1) AU2005273612B2 (el)
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CA (1) CA2576297C (el)
CR (1) CR8918A (el)
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CY (1) CY1108788T1 (el)
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EC (1) ECSP077232A (el)
ES (1) ES2314690T3 (el)
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NO (1) NO339320B1 (el)
NZ (1) NZ552868A (el)
PL (1) PL1778686T3 (el)
PT (1) PT1778686E (el)
SI (1) SI1778686T1 (el)
SV (1) SV2006002193A (el)
TN (1) TNSN07050A1 (el)
WO (1) WO2006018718A2 (el)

Families Citing this family (29)

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