HN2005000418A - Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38 - Google Patents
Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38Info
- Publication number
- HN2005000418A HN2005000418A HN2005000418A HN2005000418A HN2005000418A HN 2005000418 A HN2005000418 A HN 2005000418A HN 2005000418 A HN2005000418 A HN 2005000418A HN 2005000418 A HN2005000418 A HN 2005000418A HN 2005000418 A HN2005000418 A HN 2005000418A
- Authority
- HN
- Honduras
- Prior art keywords
- derivatives
- inhibitors
- triazolopiridinilsulfanilo
- quinasa
- map
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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Abstract
ESTA INVENCION SE REFIERE A DERIVADOS DE TRIAZOLOPIRIDINILSULFANILO, MAS PARTICULARMENTE ESTA INVENCION SE REFIERE A DERIVADOS DE PIRAZOLIL-[(TRIAZOLOPIRIDINILSULFANIL)-BENCIL]UREA Y A PROCEDIMIENTOS PARA LA PREPARACION DE, A INTERMEDIOS USADOS EN LA PREPARACION DE, A COMPOSICIONES QUE CONTIENEN Y USOS DE TALES DERIVADOS.- LOS DERIVADOS DE LA PRESENTE INVENCION SON INHIBIDORES DE LA PROTEINA QUINASA ACTIVADA POR MITOGENOS P38 (MAPK P38, QUINASA P38 O P38), PARTICULARMENTE QUINASA P38a Y SON INHIBIDORES DE LA PRODUCCION DEL FACTOR DE NECROSIS TUMORAL (TNF) PARTICULARMENTE TNFa.- TIENEN APLICACIONES TERAPEUTICAS, PARTICULARMENTE EN EL TRATAMIENTO DE ENFERMEDADES ALERGICAS Y NO ALERGICAS DE LAS VIAS RESPIRATORIAS, MAS PARTICULARMENTE ENFERMEDADES OBSTRUCTIVAS O INFLAMATORIAS D ELAS VIAS RESPIRATORIAS COMO LA ENFERMEDAD PULMONAR OBSTRUCTIVA CRONICA (COPD).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0418015A GB0418015D0 (en) | 2004-08-12 | 2004-08-12 | New compounds |
US69155905P | 2005-06-17 | 2005-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
HN2005000418A true HN2005000418A (es) | 2009-12-07 |
Family
ID=35783420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HN2005000418A HN2005000418A (es) | 2004-08-12 | 2005-08-10 | Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38 |
Country Status (35)
Country | Link |
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US (2) | US7511057B2 (es) |
EP (1) | EP1778686B9 (es) |
JP (1) | JP4084836B2 (es) |
AP (1) | AP2326A (es) |
AR (1) | AR050692A1 (es) |
AT (1) | ATE412652T1 (es) |
AU (1) | AU2005273612B2 (es) |
BR (1) | BRPI0514255A (es) |
CA (1) | CA2576297C (es) |
CR (1) | CR8918A (es) |
CU (1) | CU23497A3 (es) |
CY (1) | CY1108788T1 (es) |
DE (1) | DE602005010714D1 (es) |
DK (1) | DK1778686T3 (es) |
EA (1) | EA012119B1 (es) |
EC (1) | ECSP077232A (es) |
ES (1) | ES2314690T3 (es) |
GE (1) | GEP20104973B (es) |
GT (1) | GT200500218A (es) |
HK (1) | HK1105536A1 (es) |
HN (1) | HN2005000418A (es) |
HR (1) | HRP20080608T3 (es) |
IL (1) | IL181047A (es) |
MA (1) | MA28798B1 (es) |
MX (1) | MX2007001759A (es) |
MY (1) | MY140021A (es) |
NL (1) | NL1029726C2 (es) |
NO (1) | NO339320B1 (es) |
NZ (1) | NZ552868A (es) |
PL (1) | PL1778686T3 (es) |
PT (1) | PT1778686E (es) |
SI (1) | SI1778686T1 (es) |
SV (1) | SV2006002193A (es) |
TN (1) | TNSN07050A1 (es) |
WO (1) | WO2006018718A2 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7572807B2 (en) * | 2005-06-09 | 2009-08-11 | Bristol-Myers Squibb Company | Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors |
US7579360B2 (en) * | 2005-06-09 | 2009-08-25 | Bristol-Myers Squibb Company | Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
EP1984363A1 (en) * | 2006-02-09 | 2008-10-29 | Pfizer Limited | Triazolopyridine compounds |
JP5244369B2 (ja) * | 2006-11-10 | 2013-07-24 | 富士フイルム株式会社 | 5−アミノピラゾール誘導体の製造方法、アゾ色素 |
EP1992344A1 (en) | 2007-05-18 | 2008-11-19 | Institut Curie | P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation |
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