ECSP024404A - Ligandos para receptores de melanocortina - Google Patents

Ligandos para receptores de melanocortina

Info

Publication number
ECSP024404A
ECSP024404A EC2002004404A ECSP024404A ECSP024404A EC SP024404 A ECSP024404 A EC SP024404A EC 2002004404 A EC2002004404 A EC 2002004404A EC SP024404 A ECSP024404 A EC SP024404A EC SP024404 A ECSP024404 A EC SP024404A
Authority
EC
Ecuador
Prior art keywords
ligands
melanocortine
receptors
melanocortine receptors
het
Prior art date
Application number
EC2002004404A
Other languages
English (en)
Inventor
Philip Albert Carpino
Bradley Paul Morgan
Bridget Mccarthy Cole
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ECSP024404A publication Critical patent/ECSP024404A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

Un compuesto de la fórmula. En la que R3, R4, R6, R7, X4, Q y HET son como se han definido anteriormente, útiles para el tratamiento o la prevención de trastornos, enfermedades o procesos sensibles a la activación del receptor de melanocortina.
EC2002004404A 2000-06-28 2002-12-26 Ligandos para receptores de melanocortina ECSP024404A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21461600P 2000-06-28 2000-06-28

Publications (1)

Publication Number Publication Date
ECSP024404A true ECSP024404A (es) 2003-02-06

Family

ID=22799775

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2002004404A ECSP024404A (es) 2000-06-28 2002-12-26 Ligandos para receptores de melanocortina

Country Status (26)

Country Link
US (1) US20020072604A1 (es)
EP (1) EP1294719A1 (es)
JP (1) JP2004501917A (es)
KR (1) KR20030017571A (es)
CN (1) CN1440406A (es)
AP (1) AP2001002196A0 (es)
AR (1) AR030301A1 (es)
AU (1) AU2001260548A1 (es)
BG (1) BG107268A (es)
BR (1) BR0111567A (es)
CA (1) CA2412563A1 (es)
EA (1) EA200201119A1 (es)
EC (1) ECSP024404A (es)
IL (1) IL152781A0 (es)
IS (1) IS6617A (es)
MA (1) MA26920A1 (es)
MX (1) MXPA03000063A (es)
NO (1) NO20026280D0 (es)
OA (1) OA12296A (es)
PA (1) PA8521501A1 (es)
PE (1) PE20020208A1 (es)
PL (1) PL360855A1 (es)
TN (1) TNSN01097A1 (es)
UY (1) UY26804A1 (es)
WO (1) WO2002000654A1 (es)
ZA (1) ZA200210277B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1289526A4 (en) * 2000-05-30 2005-03-16 Merck & Co Inc MELANOCORTIN RECEPTOR AGONISTS
CA2438272A1 (en) 2001-03-02 2002-10-10 John Macor Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
US6911447B2 (en) 2001-04-25 2005-06-28 The Procter & Gamble Company Melanocortin receptor ligands
US7655658B2 (en) * 2001-08-10 2010-02-02 Palatin Technologies, Inc. Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
US7732451B2 (en) * 2001-08-10 2010-06-08 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule
US7718802B2 (en) 2001-08-10 2010-05-18 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
EP1425029A4 (en) 2001-08-10 2006-06-07 Palatin Technologies Inc PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES
US7354923B2 (en) * 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7456184B2 (en) * 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
US7084156B2 (en) 2001-11-27 2006-08-01 Merck & Co., Inc. 2-Aminoquinoline compounds
US7026335B2 (en) 2002-04-30 2006-04-11 The Procter & Gamble Co. Melanocortin receptor ligands
US7132539B2 (en) 2002-10-23 2006-11-07 The Procter & Gamble Company Melanocortin receptor ligands
AU2004209505B2 (en) 2003-02-10 2009-07-23 Banyu Pharmaceutical Co., Ltd. Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient
US7968548B2 (en) 2003-05-01 2011-06-28 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine compounds with diamine groups
US7727990B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine and keto-piperazine compounds
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
WO2005021555A1 (ja) * 2003-08-29 2005-03-10 Takeda Pharmaceutical Company Limited 二環性ピペラジン化合物およびその用途
JP2005306839A (ja) * 2003-08-29 2005-11-04 Takeda Chem Ind Ltd 二環性ピペラジン化合物およびその用途
ATE498678T1 (de) * 2004-04-08 2011-03-15 Astellas Pharma Inc Verbindung ws727713
US7709484B1 (en) 2004-04-19 2010-05-04 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
AU2006269261B2 (en) * 2005-07-08 2009-12-17 Ipsen Pharma S.A.S. Melanocortin receptor ligands
JP2009503020A (ja) 2005-08-03 2009-01-29 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 肥満症の治療におけるフリバンセリンの使用
EP1945214A1 (en) 2005-10-29 2008-07-23 Boehringer Ingelheim International GmbH Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders
PE20080145A1 (es) * 2006-03-21 2008-02-11 Janssen Pharmaceutica Nv Tetrahidro-pirimidoazepinas como moduladores de trpv1
DE602007004615D1 (de) 2006-06-30 2010-03-18 Boehringer Ingelheim Pharma Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen
EP2039695A4 (en) * 2006-07-11 2010-09-15 Takeda Pharmaceutical BICYCLIC HETEROCYLIC COMPOUND AND ITS USE
US7834017B2 (en) 2006-08-11 2010-11-16 Palatin Technologies, Inc. Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents
CA2660476C (en) 2006-08-14 2015-11-17 Boehringer Ingelheim International Gmbh Formulations of flibanserin and method for manufacturing the same
CA2661613C (en) 2006-08-25 2016-01-26 Boehringer Ingelheim International Gmbh Controlled release system and method for manufacturing the same
ES2618315T3 (es) 2007-05-25 2017-06-21 Ipsen Pharma S.A.S. Ligandos del receptor de melanocortina modificados con hidantoína
PE20091188A1 (es) 2007-09-12 2009-08-31 Boehringer Ingelheim Int Compuesto 1-[2-(4-(3-trifluorometil-fenil)piperazin-1-il)etil]-2,3-dihidro-1h-benzimidazol-2-ona (flibanserina), sus sales de adicion y composiciones farmaceuticas que los contienen
PE20091102A1 (es) 2007-12-17 2009-07-25 Janssen Pharmaceutica Nv Moduladores imidazolo-, oxazolo-, y tiazolopirimidina del trpv1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3768799A (en) * 1998-04-28 1999-11-16 Trega Biosciences, Inc. Isoquinoline compound melanocortin receptor ligands and methods of using same
CA2334551A1 (en) * 1998-06-11 1999-12-16 Merck & Co., Inc. Spiropiperidine derivatives as melanocortin receptor agonists
WO2000074679A1 (en) * 1999-06-04 2000-12-14 Merck & Co., Inc. Substituted piperidines as melanocortin-4 receptor agonists

Also Published As

Publication number Publication date
BG107268A (en) 2003-06-30
PE20020208A1 (es) 2002-03-13
TNSN01097A1 (fr) 2005-11-10
UY26804A1 (es) 2002-01-31
CN1440406A (zh) 2003-09-03
IS6617A (is) 2002-11-14
AR030301A1 (es) 2003-08-20
MXPA03000063A (es) 2003-09-25
WO2002000654A1 (en) 2002-01-03
US20020072604A1 (en) 2002-06-13
PA8521501A1 (es) 2002-10-24
EP1294719A1 (en) 2003-03-26
IL152781A0 (en) 2003-06-24
MA26920A1 (fr) 2004-12-20
CA2412563A1 (en) 2002-01-03
EA200201119A1 (ru) 2003-06-26
KR20030017571A (ko) 2003-03-03
BR0111567A (pt) 2003-05-06
AU2001260548A1 (en) 2002-01-08
AP2001002196A0 (en) 2002-12-21
JP2004501917A (ja) 2004-01-22
PL360855A1 (en) 2004-09-20
NO20026280L (no) 2002-12-30
OA12296A (en) 2006-05-12
ZA200210277B (en) 2003-12-19
NO20026280D0 (no) 2002-12-30

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