PA8521501A1 - Ligandos para receptores de melanocortina - Google Patents

Ligandos para receptores de melanocortina

Info

Publication number
PA8521501A1
PA8521501A1 PA20018521501A PA8521501A PA8521501A1 PA 8521501 A1 PA8521501 A1 PA 8521501A1 PA 20018521501 A PA20018521501 A PA 20018521501A PA 8521501 A PA8521501 A PA 8521501A PA 8521501 A1 PA8521501 A1 PA 8521501A1
Authority
PA
Panama
Prior art keywords
ligands
melanocortine
receptors
melanocortine receptors
het
Prior art date
Application number
PA20018521501A
Other languages
English (en)
Inventor
Cole Bridget Mccarthy
Bradley Paul Morgan
Philip Albert Carpino
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PA8521501A1 publication Critical patent/PA8521501A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

UN COMPUESTO DE FORMULA 1 EN LA QUE R3, R4, R6, R7, X4, Q Y HET SON COMO SE HAN DEFINIDO ANTERIORMENTE, UTILES PARA EL TRATAMIENTO O LA PREVENCION DE TRASTORNOS, ENFERMEDADES O PROCESOS SENSIBLES A LA ACTIVACION DEL RECEPTOR DE MELANOCORTINA.
PA20018521501A 2000-06-28 2001-06-28 Ligandos para receptores de melanocortina PA8521501A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21461600P 2000-06-28 2000-06-28

Publications (1)

Publication Number Publication Date
PA8521501A1 true PA8521501A1 (es) 2002-10-24

Family

ID=22799775

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20018521501A PA8521501A1 (es) 2000-06-28 2001-06-28 Ligandos para receptores de melanocortina

Country Status (26)

Country Link
US (1) US20020072604A1 (es)
EP (1) EP1294719A1 (es)
JP (1) JP2004501917A (es)
KR (1) KR20030017571A (es)
CN (1) CN1440406A (es)
AP (1) AP2001002196A0 (es)
AR (1) AR030301A1 (es)
AU (1) AU2001260548A1 (es)
BG (1) BG107268A (es)
BR (1) BR0111567A (es)
CA (1) CA2412563A1 (es)
EA (1) EA200201119A1 (es)
EC (1) ECSP024404A (es)
IL (1) IL152781A0 (es)
IS (1) IS6617A (es)
MA (1) MA26920A1 (es)
MX (1) MXPA03000063A (es)
NO (1) NO20026280D0 (es)
OA (1) OA12296A (es)
PA (1) PA8521501A1 (es)
PE (1) PE20020208A1 (es)
PL (1) PL360855A1 (es)
TN (1) TNSN01097A1 (es)
UY (1) UY26804A1 (es)
WO (1) WO2002000654A1 (es)
ZA (1) ZA200210277B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2410597A1 (en) * 2000-05-30 2001-12-06 Merck & Co., Inc. Melanocortin receptor agonists
EP1363631A4 (en) 2001-03-02 2005-11-16 Bristol Myers Squibb Co "COMPOUNDS SUITED AS MODULATORS OF MELANOCORTIN RECEPTORS AND THESE PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF"
US6911447B2 (en) * 2001-04-25 2005-06-28 The Procter & Gamble Company Melanocortin receptor ligands
US7655658B2 (en) * 2001-08-10 2010-02-02 Palatin Technologies, Inc. Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
US7354923B2 (en) * 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7718802B2 (en) 2001-08-10 2010-05-18 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US7732451B2 (en) * 2001-08-10 2010-06-08 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule
US7456184B2 (en) * 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
AU2002331064B2 (en) 2001-08-10 2007-08-23 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
CA2468015A1 (en) 2001-11-27 2003-06-05 Merck & Co., Inc. 2-aminoquinoline compounds
US7026335B2 (en) 2002-04-30 2006-04-11 The Procter & Gamble Co. Melanocortin receptor ligands
TW200504033A (en) 2002-10-23 2005-02-01 Procter & Gamble Melanocortin receptor ligands
JPWO2004069798A1 (ja) 2003-02-10 2006-05-25 萬有製薬株式会社 ピペリジン誘導体を有効成分とするメラニン凝集ホルモン受容体拮抗剤
US7727990B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine and keto-piperazine compounds
US7968548B2 (en) 2003-05-01 2011-06-28 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine compounds with diamine groups
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
JP2005306839A (ja) * 2003-08-29 2005-11-04 Takeda Chem Ind Ltd 二環性ピペラジン化合物およびその用途
EP1661898A4 (en) 2003-08-29 2009-04-15 Takeda Pharmaceutical BICYCLIC PIPERAZINE COMPOUND AND USE THEREOF
PT1751273E (pt) * 2004-04-08 2011-03-07 Astellas Pharma Inc Composto ws727713
US7709484B1 (en) 2004-04-19 2010-05-04 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
WO2007008704A2 (en) * 2005-07-08 2007-01-18 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Melanocortin receptor ligands
EP1912650B8 (en) 2005-08-03 2017-10-18 Sprout Pharmaceuticals, Inc. Use of flibanserin in the treatment of obesity
US7923449B2 (en) 2005-10-29 2011-04-12 Boehringer Ingelheim International Gmbh Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders
PE20080145A1 (es) 2006-03-21 2008-02-11 Janssen Pharmaceutica Nv Tetrahidro-pirimidoazepinas como moduladores de trpv1
DE602007004615D1 (de) 2006-06-30 2010-03-18 Boehringer Ingelheim Pharma Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen
US20100004249A1 (en) * 2006-07-11 2010-01-07 Takahiro Matsumoto Bicyclic heterocyclic compound and use thereof
US7834017B2 (en) 2006-08-11 2010-11-16 Palatin Technologies, Inc. Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents
BRPI0716439B8 (pt) 2006-08-14 2021-05-25 Boehringer Ingelheim Int sistemas de liberação farmacêutico compreendendo flibanserina, processo para preparação e uso dos mesmos
JP5220746B2 (ja) 2006-08-25 2013-06-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 制御放出システム及びその製造方法
JP5250026B2 (ja) 2007-05-25 2013-07-31 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ ヒダントインで修飾したメラノコルチン受容体リガンド
UY31335A1 (es) 2007-09-12 2009-04-30 Tratamiento de sintomas vasomotores
EP2224929B1 (en) 2007-12-17 2016-05-04 Janssen Pharmaceutica, N.V. Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of trpv1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3768799A (en) * 1998-04-28 1999-11-16 Trega Biosciences, Inc. Isoquinoline compound melanocortin receptor ligands and methods of using same
CA2334551A1 (en) * 1998-06-11 1999-12-16 Merck & Co., Inc. Spiropiperidine derivatives as melanocortin receptor agonists
EP1187614A4 (en) * 1999-06-04 2005-06-22 Merck & Co Inc SUBSTITUTED PIPERIDINES THAN MELANOCORTIN-4 RECEPTOR AGONISTS

Also Published As

Publication number Publication date
IS6617A (is) 2002-11-14
AP2001002196A0 (en) 2002-12-21
KR20030017571A (ko) 2003-03-03
JP2004501917A (ja) 2004-01-22
PE20020208A1 (es) 2002-03-13
BR0111567A (pt) 2003-05-06
PL360855A1 (en) 2004-09-20
EA200201119A1 (ru) 2003-06-26
EP1294719A1 (en) 2003-03-26
US20020072604A1 (en) 2002-06-13
ZA200210277B (en) 2003-12-19
MXPA03000063A (es) 2003-09-25
BG107268A (en) 2003-06-30
TNSN01097A1 (fr) 2005-11-10
ECSP024404A (es) 2003-02-06
CA2412563A1 (en) 2002-01-03
NO20026280L (no) 2002-12-30
CN1440406A (zh) 2003-09-03
AR030301A1 (es) 2003-08-20
AU2001260548A1 (en) 2002-01-08
NO20026280D0 (no) 2002-12-30
IL152781A0 (en) 2003-06-24
OA12296A (en) 2006-05-12
WO2002000654A1 (en) 2002-01-03
UY26804A1 (es) 2002-01-31
MA26920A1 (fr) 2004-12-20

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