TNSN01097A1 - Ligands nouveaux recepteurs de melanocortines, et compositions les contenant - Google Patents

Ligands nouveaux recepteurs de melanocortines, et compositions les contenant

Info

Publication number
TNSN01097A1
TNSN01097A1 TNTNSN01097A TNSN01097A TNSN01097A1 TN SN01097 A1 TNSN01097 A1 TN SN01097A1 TN TNSN01097 A TNTNSN01097 A TN TNSN01097A TN SN01097 A TNSN01097 A TN SN01097A TN SN01097 A1 TNSN01097 A1 TN SN01097A1
Authority
TN
Tunisia
Prior art keywords
compositions containing
melanocortin receptors
novel melanocortin
compound
novel
Prior art date
Application number
TNTNSN01097A
Other languages
English (en)
Inventor
Albert Carpino Philip
Mccarthy Cole Bridget
Paul Morgan Bradley
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TNSN01097A1 publication Critical patent/TNSN01097A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'INVENTION CONCERNE UN COMPOSE DE FORMULE (I) : DANS LAQUELLE R3, R4, R6, R7 et X4 REPRESENTENT L'HYDROGENE OU DES RADICAUX ORGANIQUES, Q EST UNE LIAISON COVALENTE OU UN GROUPE CH2, ET HET EST UN GROUPEMENT HETEROCYCLIQUE ; CE COMPOSE EST UTILE POUR LE TRAITEMENT CURATIF OU PREVENTIF DE DEREGLEMENTS, DE MALADIES OU D'ETATS PATHOLOGIQUES SENSIBLES A L'ACTIVATION DU RECEPTEUR DE MELANOCORTINE.
TNTNSN01097A 2000-06-28 2001-06-27 Ligands nouveaux recepteurs de melanocortines, et compositions les contenant TNSN01097A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21461600P 2000-06-28 2000-06-28

Publications (1)

Publication Number Publication Date
TNSN01097A1 true TNSN01097A1 (fr) 2005-11-10

Family

ID=22799775

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN01097A TNSN01097A1 (fr) 2000-06-28 2001-06-27 Ligands nouveaux recepteurs de melanocortines, et compositions les contenant

Country Status (26)

Country Link
US (1) US20020072604A1 (fr)
EP (1) EP1294719A1 (fr)
JP (1) JP2004501917A (fr)
KR (1) KR20030017571A (fr)
CN (1) CN1440406A (fr)
AP (1) AP2001002196A0 (fr)
AR (1) AR030301A1 (fr)
AU (1) AU2001260548A1 (fr)
BG (1) BG107268A (fr)
BR (1) BR0111567A (fr)
CA (1) CA2412563A1 (fr)
EA (1) EA200201119A1 (fr)
EC (1) ECSP024404A (fr)
IL (1) IL152781A0 (fr)
IS (1) IS6617A (fr)
MA (1) MA26920A1 (fr)
MX (1) MXPA03000063A (fr)
NO (1) NO20026280L (fr)
OA (1) OA12296A (fr)
PA (1) PA8521501A1 (fr)
PE (1) PE20020208A1 (fr)
PL (1) PL360855A1 (fr)
TN (1) TNSN01097A1 (fr)
UY (1) UY26804A1 (fr)
WO (1) WO2002000654A1 (fr)
ZA (1) ZA200210277B (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001091752A1 (fr) * 2000-05-30 2001-12-06 Merck & Co., Inc. Agonistes du recepteur de la melanocortine
CA2438272A1 (fr) 2001-03-02 2002-10-10 John Macor Composes utiles comme modulateurs des recepteurs de la melanocortine et compositions pharmaceutiques renfermant ceux-ci
US6911447B2 (en) 2001-04-25 2005-06-28 The Procter & Gamble Company Melanocortin receptor ligands
US7718802B2 (en) 2001-08-10 2010-05-18 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US7655658B2 (en) * 2001-08-10 2010-02-02 Palatin Technologies, Inc. Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
US7354923B2 (en) * 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7732451B2 (en) * 2001-08-10 2010-06-08 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule
AU2002331064B2 (en) * 2001-08-10 2007-08-23 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
US7456184B2 (en) * 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
JP2005519876A (ja) 2001-11-27 2005-07-07 メルク　エンド　カムパニー　インコーポレーテッド ２−アミノキノリン化合物
US7026335B2 (en) 2002-04-30 2006-04-11 The Procter & Gamble Co. Melanocortin receptor ligands
TW200504033A (en) 2002-10-23 2005-02-01 Procter & Gamble Melanocortin receptor ligands
WO2004069798A1 (fr) 2003-02-10 2004-08-19 Banyu Pharmaceutical Co.,Ltd. Antagonistes des recepteurs de l'hormone concentrant la melanine contenant des derives de piperidine en tant que principe actif
US7727990B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine and keto-piperazine compounds
US7968548B2 (en) 2003-05-01 2011-06-28 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine compounds with diamine groups
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
EP1661898A4 (fr) * 2003-08-29 2009-04-15 Takeda Pharmaceutical Compose de piperazine bicyclique et utilisation de ce dernier
JP2005306839A (ja) * 2003-08-29 2005-11-04 Takeda Chem Ind Ltd 二環性ピペラジン化合物およびその用途
KR20100118615A (ko) * 2004-04-08 2010-11-05 아스테라스 세이야쿠 가부시키가이샤 화합물 ｗｓ727713
US7709484B1 (en) 2004-04-19 2010-05-04 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
EP2236151B1 (fr) * 2005-07-08 2012-05-23 Ipsen Pharma Ligands des récepteurs de la melanocortine
JP2009503020A (ja) 2005-08-03 2009-01-29 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 肥満症の治療におけるフリバンセリンの使用
EP1945214A1 (fr) 2005-10-29 2008-07-23 Boehringer Ingelheim International GmbH Derives de benzimidazolone utiles pour le traitement des troubles premenstruels et d'autres troubles sexuels chez la femme
PE20080145A1 (es) 2006-03-21 2008-02-11 Janssen Pharmaceutica Nv Tetrahidro-pirimidoazepinas como moduladores de trpv1
DE602007004615D1 (de) 2006-06-30 2010-03-18 Boehringer Ingelheim Pharma Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen
JPWO2008007664A1 (ja) 2006-07-11 2009-12-10 武田薬品工業株式会社 二環性複素環化合物およびその用途
US7834017B2 (en) 2006-08-11 2010-11-16 Palatin Technologies, Inc. Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents
JP5793828B2 (ja) 2006-08-14 2015-10-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング フリバンセリンの製剤及びその製造方法
CN101505736A (zh) 2006-08-25 2009-08-12 贝林格尔.英格海姆国际有限公司 控制释放系统及其制造方法
CA2689016C (fr) 2007-05-25 2014-08-12 Ipsen Pharma S.A.S. Ligands de recepteurs de la melanocortine modifies au moyen d'hydantoine
PE20091188A1 (es) 2007-09-12 2009-08-31 Boehringer Ingelheim Int Compuesto 1-[2-(4-(3-trifluorometil-fenil)piperazin-1-il)etil]-2,3-dihidro-1h-benzimidazol-2-ona (flibanserina), sus sales de adicion y composiciones farmaceuticas que los contienen
EP2224929B1 (fr) 2007-12-17 2016-05-04 Janssen Pharmaceutica, N.V. Modulateurs imidazolo-, oxazolo- et thiazolopyrimidines de trpv1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3768799A (en) * 1998-04-28 1999-11-16 Trega Biosciences, Inc. Isoquinoline compound melanocortin receptor ligands and methods of using same
EP1085869A4 (fr) * 1998-06-11 2001-10-04 Merck & Co Inc Derives de spiropiperidine en tant qu'agonistes des recepteurs de la melanocortine
JP2003505435A (ja) * 1999-06-04 2003-02-12 メルク エンド カムパニー インコーポレーテッド メラノコルチン−４受容体ゴニストとしての置換ピペリジン

Also Published As

Publication number Publication date
ECSP024404A (es) 2003-02-06
PA8521501A1 (es) 2002-10-24
UY26804A1 (es) 2002-01-31
AU2001260548A1 (en) 2002-01-08
NO20026280D0 (no) 2002-12-30
AP2001002196A0 (en) 2002-12-21
MA26920A1 (fr) 2004-12-20
BG107268A (en) 2003-06-30
MXPA03000063A (es) 2003-09-25
EP1294719A1 (fr) 2003-03-26
JP2004501917A (ja) 2004-01-22
ZA200210277B (en) 2003-12-19
CN1440406A (zh) 2003-09-03
US20020072604A1 (en) 2002-06-13
KR20030017571A (ko) 2003-03-03
CA2412563A1 (fr) 2002-01-03
IL152781A0 (en) 2003-06-24
PE20020208A1 (es) 2002-03-13
IS6617A (is) 2002-11-14
PL360855A1 (en) 2004-09-20
WO2002000654A1 (fr) 2002-01-03
BR0111567A (pt) 2003-05-06
OA12296A (en) 2006-05-12
EA200201119A1 (ru) 2003-06-26
AR030301A1 (es) 2003-08-20
NO20026280L (no) 2002-12-30

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