EA202091974A1 - Связывающие bcma антитела и их применение - Google Patents
Связывающие bcma антитела и их применениеInfo
- Publication number
- EA202091974A1 EA202091974A1 EA202091974A EA202091974A EA202091974A1 EA 202091974 A1 EA202091974 A1 EA 202091974A1 EA 202091974 A EA202091974 A EA 202091974A EA 202091974 A EA202091974 A EA 202091974A EA 202091974 A1 EA202091974 A1 EA 202091974A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- bcma
- antibodies
- patient
- binders
- application
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862633152P | 2018-02-21 | 2018-02-21 | |
| PCT/US2019/018698 WO2019164891A1 (en) | 2018-02-21 | 2019-02-20 | Bcma-binding antibodies and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA202091974A1 true EA202091974A1 (ru) | 2020-12-08 |
Family
ID=65686040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202091974A EA202091974A1 (ru) | 2018-02-21 | 2019-02-20 | Связывающие bcma антитела и их применение |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11401336B2 (https=) |
| EP (1) | EP3755718A1 (https=) |
| JP (1) | JP2021514193A (https=) |
| KR (1) | KR20200123155A (https=) |
| CN (1) | CN112272675A (https=) |
| AR (1) | AR115257A1 (https=) |
| AU (1) | AU2019223076A1 (https=) |
| BR (1) | BR112020017053A2 (https=) |
| CA (1) | CA3092037A1 (https=) |
| EA (1) | EA202091974A1 (https=) |
| IL (1) | IL276548A (https=) |
| MX (1) | MX2020008718A (https=) |
| SG (1) | SG11202007495SA (https=) |
| TW (1) | TW202000701A (https=) |
| WO (1) | WO2019164891A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021099944A1 (en) | 2019-11-18 | 2021-05-27 | Janssen Biotech, Inc. | Anti-cd79 chimeric antigen receptors, car-t cells, and uses thereof |
| CN115803027A (zh) * | 2020-04-30 | 2023-03-14 | 百时美施贵宝公司 | 治疗细胞因子相关的不良事件的方法 |
| MX2023003041A (es) | 2020-09-16 | 2023-05-09 | Amgen Inc | Métodos para administrar dosis terapéuticas de moléculas de acoplamiento a células t biespecíficas para el tratamiento de cáncer. |
| AU2022207648A1 (en) | 2021-01-13 | 2023-07-27 | Monte Rosa Therapeutics Ag | Isoindolinone compounds |
| US20250276092A1 (en) * | 2024-03-01 | 2025-09-04 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for re-dosing aav using anti-cd40 antagonistic antibody to suppress host anti-aav antibody response |
| WO2026072671A1 (en) | 2024-09-24 | 2026-04-02 | City Of Hope | Methods comprising oncolytic viruses expressing bcmat and bcma-targeted therapies |
| WO2026072709A1 (en) | 2024-09-25 | 2026-04-02 | Orna Therapeutics, Inc. | Chimeric antigen receptors targeting bcma |
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| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
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| KR102526945B1 (ko) * | 2014-04-30 | 2023-04-27 | 막스-델부뤽-센트럼 퓌어 몰레쿨라레 메디친 인 데어 헬름홀츠-게마인샤프트 | Ｃｄ269에 대한 인간화 항체 |
| BR112017001183A2 (pt) * | 2014-07-21 | 2017-11-28 | Novartis Ag | tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado |
| EP3023437A1 (en) * | 2014-11-20 | 2016-05-25 | EngMab AG | Bispecific antibodies against CD3epsilon and BCMA |
| HRP20191873T1 (hr) * | 2014-12-12 | 2020-01-24 | Bluebird Bio, Inc. | Kimerni antigenski receptori |
| US9713375B1 (en) | 2015-02-26 | 2017-07-25 | Brett Einar Rahm | Collapsible portable table |
| TWI703159B (zh) | 2015-04-13 | 2020-09-01 | 美商輝瑞股份有限公司 | Bcma特異性治療性抗體及其用途 |
| US10294304B2 (en) | 2015-04-13 | 2019-05-21 | Pfizer Inc. | Chimeric antigen receptors targeting B-cell maturation antigen |
| SI3331910T1 (sl) | 2015-08-03 | 2020-07-31 | Engmab Sarl | Monoklonska protitelesa proti humani antigen dozorevanja limfocitov B (BCMA) |
| CN108473575B (zh) * | 2015-11-13 | 2022-04-19 | 美国卫生和人力服务部 | 抗-bcma多肽和蛋白质 |
| TWI795133B (zh) * | 2016-04-01 | 2023-03-01 | 美商凱特製藥公司 | Ｂｃｍａ結合分子類及彼等之用途 |
| KR20250175345A (ko) * | 2016-06-21 | 2025-12-16 | 테네오바이오, 인코포레이티드 | Cd3 결합 항체 |
-
2019
- 2019-02-20 BR BR112020017053-4A patent/BR112020017053A2/pt not_active IP Right Cessation
- 2019-02-20 WO PCT/US2019/018698 patent/WO2019164891A1/en not_active Ceased
- 2019-02-20 US US16/971,925 patent/US11401336B2/en active Active
- 2019-02-20 AU AU2019223076A patent/AU2019223076A1/en not_active Abandoned
- 2019-02-20 MX MX2020008718A patent/MX2020008718A/es unknown
- 2019-02-20 CA CA3092037A patent/CA3092037A1/en active Pending
- 2019-02-20 KR KR1020207026078A patent/KR20200123155A/ko not_active Withdrawn
- 2019-02-20 SG SG11202007495SA patent/SG11202007495SA/en unknown
- 2019-02-20 JP JP2020544223A patent/JP2021514193A/ja active Pending
- 2019-02-20 EP EP19709253.9A patent/EP3755718A1/en not_active Withdrawn
- 2019-02-20 CN CN201980027397.4A patent/CN112272675A/zh active Pending
- 2019-02-20 EA EA202091974A patent/EA202091974A1/ru unknown
- 2019-02-21 TW TW108105895A patent/TW202000701A/zh unknown
- 2019-02-22 AR ARP190100439A patent/AR115257A1/es not_active Application Discontinuation
-
2020
- 2020-08-06 IL IL276548A patent/IL276548A/en unknown
-
2022
- 2022-06-17 US US17/807,473 patent/US20220324991A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20220324991A1 (en) | 2022-10-13 |
| US11401336B2 (en) | 2022-08-02 |
| WO2019164891A9 (en) | 2020-09-17 |
| JP2021514193A (ja) | 2021-06-10 |
| BR112020017053A2 (pt) | 2020-12-15 |
| MX2020008718A (es) | 2020-12-07 |
| AU2019223076A1 (en) | 2020-10-08 |
| TW202000701A (zh) | 2020-01-01 |
| WO2019164891A1 (en) | 2019-08-29 |
| AR115257A1 (es) | 2020-12-16 |
| US20200399386A1 (en) | 2020-12-24 |
| KR20200123155A (ko) | 2020-10-28 |
| CN112272675A (zh) | 2021-01-26 |
| EP3755718A1 (en) | 2020-12-30 |
| IL276548A (en) | 2020-09-30 |
| CA3092037A1 (en) | 2019-08-29 |
| SG11202007495SA (en) | 2020-09-29 |
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