EA202091365A1 - Комбинации ацетиллейцина для лечения головокружения - Google Patents
Комбинации ацетиллейцина для лечения головокруженияInfo
- Publication number
- EA202091365A1 EA202091365A1 EA202091365A EA202091365A EA202091365A1 EA 202091365 A1 EA202091365 A1 EA 202091365A1 EA 202091365 A EA202091365 A EA 202091365A EA 202091365 A EA202091365 A EA 202091365A EA 202091365 A1 EA202091365 A1 EA 202091365A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- treatment
- combinations
- acetylleucine
- visits
- vestibular
- Prior art date
Links
- WXNXCEHXYPACJF-ZETCQYMHSA-N N-acetyl-L-leucine Chemical compound CC(C)C[C@@H](C(O)=O)NC(C)=O WXNXCEHXYPACJF-ZETCQYMHSA-N 0.000 title abstract 2
- 229960000669 acetylleucine Drugs 0.000 title abstract 2
- 206010003591 Ataxia Diseases 0.000 abstract 1
- RZZPDXZPRHQOCG-OJAKKHQRSA-M CDP-choline(1-) Chemical compound O[C@@H]1[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OCC[N+](C)(C)C)O[C@H]1N1C(=O)N=C(N)C=C1 RZZPDXZPRHQOCG-OJAKKHQRSA-M 0.000 abstract 1
- 206010008025 Cerebellar ataxia Diseases 0.000 abstract 1
- 239000008777 Glycerylphosphorylcholine Substances 0.000 abstract 1
- 208000012886 Vertigo Diseases 0.000 abstract 1
- 229960004536 betahistine Drugs 0.000 abstract 1
- UUQMNUMQCIQDMZ-UHFFFAOYSA-N betahistine Chemical compound CNCCC1=CC=CC=N1 UUQMNUMQCIQDMZ-UHFFFAOYSA-N 0.000 abstract 1
- QWCRAEMEVRGPNT-UHFFFAOYSA-N buspirone Chemical compound C1C(=O)N(CCCCN2CCN(CC2)C=2N=CC=CN=2)C(=O)CC21CCCC2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 0.000 abstract 1
- 229960002495 buspirone Drugs 0.000 abstract 1
- 229960004788 choline alfoscerate Drugs 0.000 abstract 1
- 229960001284 citicoline Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- SUHOQUVVVLNYQR-MRVPVSSYSA-O glycerylphosphorylcholine Chemical compound C[N+](C)(C)CCO[P@](O)(=O)OC[C@H](O)CO SUHOQUVVVLNYQR-MRVPVSSYSA-O 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001720 vestibular Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Настоящее изобретение относится к области медицины и фармакологии, а именно к новым комбинациям ацетиллейцина с по меньшей мере одним веществом, выбранным из группы, включающей бетагистин, буспирон, холина альфосцерат и цитиколин, для лечения вестибулярного и невестибулярного головокружения, мозжечковой атаксии, семейной атаксии.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2017141912A RU2680413C1 (ru) | 2017-12-01 | 2017-12-01 | Комбинации ацетиллейцина для лечения головокружения |
| PCT/RU2018/000762 WO2019108093A1 (ru) | 2017-12-01 | 2018-11-20 | Комбинации ацетиллейцина для лечения головокружения |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA202091365A1 true EA202091365A1 (ru) | 2020-08-26 |
Family
ID=65479219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202091365A EA202091365A1 (ru) | 2017-12-01 | 2018-11-20 | Комбинации ацетиллейцина для лечения головокружения |
Country Status (3)
| Country | Link |
|---|---|
| EA (1) | EA202091365A1 (ru) |
| RU (1) | RU2680413C1 (ru) |
| WO (1) | WO2019108093A1 (ru) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20071492A1 (it) * | 2007-07-24 | 2009-01-25 | S I I T Srl Servizio Internazi | "composizioni per il trattamento e la prevenzione di condizioni di vertigine e acufeni comprendenti citicolina, estratto di ginkgo biloba e flavoni dimerici di ginkgo biloba" |
| RU2406506C1 (ru) * | 2009-08-17 | 2010-12-20 | Мераб Ревазович Кокеладзе | Фармацевтическая композиция холин альфосцерата в форме раствора для инъекций (холитилин®), обладающая ноотропной активностью и холиномиметическим действием, способ лечения/профилактики заболеваний цнс и последствий черепно-мозговых травм |
-
2017
- 2017-12-01 RU RU2017141912A patent/RU2680413C1/ru active
-
2018
- 2018-11-20 EA EA202091365A patent/EA202091365A1/ru unknown
- 2018-11-20 WO PCT/RU2018/000762 patent/WO2019108093A1/ru active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| RU2680413C1 (ru) | 2019-02-21 |
| WO2019108093A1 (ru) | 2019-06-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA201890725A1 (ru) | Агонисты фарнезоидного х-рецептора и их применение | |
| EA201990187A1 (ru) | Антипролиферационные средства на основе пиримидина | |
| BR112017012859A2 (pt) | fosforamidatos para o tratamento do vírus da hepatite b | |
| MD3582853T2 (ro) | Compuși di-nucleotidici ciclici pentru tratamentul cancerului | |
| EA201790630A1 (ru) | Способы получения рибозидов | |
| EA201690372A1 (ru) | Азапиридоновые соединения и их применение | |
| EA201791739A1 (ru) | Иммуномодуляторы | |
| EA201791708A1 (ru) | Иммуномодуляторы | |
| EA202090720A1 (ru) | ПРОИЗВОДНЫЕ GalNAc | |
| EA201792008A1 (ru) | Соединения азапиридона и способы их применения | |
| EA201690224A1 (ru) | Противовирусные соединения | |
| EA201891399A1 (ru) | Бипиразолильные производные, пригодные для лечения аутоиммунных заболеваний | |
| EA201992083A1 (ru) | Модуляторы соматостатина и их применения | |
| EA201690371A1 (ru) | Пиридазиноновые соединения и их применение | |
| EA201890723A1 (ru) | Производные моно- или дизамещенных индолов в качестве ингибиторов репликации вирусов денге | |
| EA201790700A1 (ru) | Моно- или дизамещенные индолы в качестве ингибиторов репликации вирусов денге | |
| EA201791614A1 (ru) | Производные индола в качестве ингибиторов репликации вирусов денге | |
| EA201992782A1 (ru) | Замещенные производные индолина в качестве ингибиторов репликации вирусов денге | |
| EA201990400A1 (ru) | Соединения и композиции и их применение | |
| EA202191476A1 (ru) | Гетероароматические соединения в качестве ингибиторов ванина | |
| EA202091020A1 (ru) | Замещенные имидазопиридинамиды и их применение | |
| EA201892265A1 (ru) | Способы лечения офтальмологических заболеваний | |
| EA201891609A1 (ru) | Производные 3-((гетеро-)арил)алкил-8-амино-2-оксо-1,3-диазаспиро[4.5]декана | |
| EA201892475A1 (ru) | Оксабороловые сложные эфиры, их применение | |
| EA201792571A1 (ru) | Терапевтическое применение l-4-хлорокинуренина |