EA201991863A1 - Составы амфетамина, препятствующие злоупотреблению - Google Patents

Составы амфетамина, препятствующие злоупотреблению

Info

Publication number
EA201991863A1
EA201991863A1 EA201991863A EA201991863A EA201991863A1 EA 201991863 A1 EA201991863 A1 EA 201991863A1 EA 201991863 A EA201991863 A EA 201991863A EA 201991863 A EA201991863 A EA 201991863A EA 201991863 A1 EA201991863 A1 EA 201991863A1
Authority
EA
Eurasian Patent Office
Prior art keywords
amphetamine
composites
preventing abuse
abuse
preventing
Prior art date
Application number
EA201991863A
Other languages
English (en)
Other versions
EA039416B1 (ru
Inventor
Дэвид Бейкер
Ярон Дэниели
Ханна Рон
Давид Синер
Original Assignee
Валлон Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Валлон Фармасьютикалз, Инк. filed Critical Валлон Фармасьютикалз, Инк.
Publication of EA201991863A1 publication Critical patent/EA201991863A1/ru
Publication of EA039416B1 publication Critical patent/EA039416B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение относится в целом к составам, препятствующим злоупотреблению, содержащим декстроамфетамина сульфат.
EA201991863A 2017-02-06 2018-02-06 Состав амфетамина, препятствующий злоупотреблению EA039416B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762455227P 2017-02-06 2017-02-06
US15/591,677 US9931303B1 (en) 2017-02-06 2017-05-10 Abuse deterrent formulations of amphetamine
PCT/US2018/017019 WO2018145071A1 (en) 2017-02-06 2018-02-06 Abuse deterrent formulations of amphetamine

Publications (2)

Publication Number Publication Date
EA201991863A1 true EA201991863A1 (ru) 2020-02-17
EA039416B1 EA039416B1 (ru) 2022-01-25

Family

ID=61724997

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201991863A EA039416B1 (ru) 2017-02-06 2018-02-06 Состав амфетамина, препятствующий злоупотреблению

Country Status (14)

Country Link
US (3) US9931303B1 (ru)
EP (2) EP3943066B1 (ru)
JP (2) JP7054709B2 (ru)
CN (1) CN110461309A (ru)
AU (1) AU2018215669B2 (ru)
BR (1) BR112019016208A2 (ru)
CA (1) CA3088959A1 (ru)
DK (2) DK3943066T3 (ru)
EA (1) EA039416B1 (ru)
ES (1) ES2890862T3 (ru)
IL (1) IL268367A (ru)
PL (1) PL3576719T3 (ru)
PT (1) PT3576719T (ru)
WO (1) WO2018145071A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9931303B1 (en) * 2017-02-06 2018-04-03 Alcobra Ltd. Abuse deterrent formulations of amphetamine
EP3473246A1 (en) * 2017-10-19 2019-04-24 Capsugel Belgium NV Immediate release abuse deterrent formulations
GB201809976D0 (en) * 2018-06-18 2018-08-01 Neurocentrx Pharma Ltd Novel formulations
US11253490B1 (en) * 2021-05-17 2022-02-22 Vallon Pharamaceuticals, Inc. Compositions and methods of treating cognitive impairment
WO2023212247A1 (en) * 2022-04-27 2023-11-02 Aardvark Therapeutics, Inc. Improved abuse-deterrent pharmaceutical composition with aversion properties

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700561B2 (en) 2002-02-22 2010-04-20 Shire Llc Abuse-resistant amphetamine prodrugs
GB0506982D0 (en) 2005-04-06 2005-05-11 Mw Encap Ltd Abuse resistant capsules
CN101193650A (zh) * 2005-04-08 2008-06-04 新河药品股份有限公司 抗滥用的苯丙胺前体药物
JP2010260812A (ja) 2009-05-01 2010-11-18 Nakanihon Capsule Co Ltd ソフトカプセル
WO2012129551A1 (en) 2011-03-23 2012-09-27 Ironshore Pharmaceuticals & Development, Inc. Methods and compositions for treatment of attention deficit disorder
FR2983409B1 (fr) * 2011-12-06 2013-12-27 Ethypharm Sa Comprime susceptible de lutter contre le detournement par voie injectable
EP2838536B1 (en) 2012-04-18 2017-08-09 Mallinckrodt LLC Immediate release pharmaceutical compositions with abuse deterrent properties
US10420729B2 (en) 2013-03-15 2019-09-24 R.P. Scherer Technologies, Llc Abuse resistant capsule
CA2817728A1 (en) * 2013-05-31 2014-11-30 Pharmascience Inc. Abuse deterrent immediate release formulation
WO2015103379A1 (en) * 2013-12-31 2015-07-09 Kashiv Pharma, Llc Abuse-resistant drug formulations
KR102454959B1 (ko) * 2014-07-31 2022-10-14 코닝 인코포레이티드 열 템퍼링된 유리 및 유리를 열 템퍼링하는 방법 및 장치
US9931303B1 (en) * 2017-02-06 2018-04-03 Alcobra Ltd. Abuse deterrent formulations of amphetamine

Also Published As

Publication number Publication date
JP7054709B2 (ja) 2022-04-14
JP2020506238A (ja) 2020-02-27
US9931303B1 (en) 2018-04-03
PL3576719T3 (pl) 2022-01-03
US20200085752A1 (en) 2020-03-19
PT3576719T (pt) 2021-09-24
ES2890862T3 (es) 2022-01-24
EP3576719B8 (en) 2022-07-13
BR112019016208A2 (pt) 2020-04-14
IL268367A (en) 2019-09-26
AU2018215669B2 (en) 2024-02-29
DK3943066T3 (da) 2023-02-20
EP3943066A1 (en) 2022-01-26
AU2018215669A1 (en) 2019-09-19
EP3576719B1 (en) 2021-07-07
US20190076367A1 (en) 2019-03-14
EP3943066B1 (en) 2022-11-23
EA039416B1 (ru) 2022-01-25
EP3576719A1 (en) 2019-12-11
JP2022091951A (ja) 2022-06-21
CA3088959A1 (en) 2018-08-09
WO2018145071A1 (en) 2018-08-09
CN110461309A (zh) 2019-11-15
US10471015B2 (en) 2019-11-12
DK3576719T3 (da) 2021-10-04
US11517537B2 (en) 2022-12-06

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