BR112019016208A2 - formulação de dissuasão de abuso de anfetamina - Google Patents

formulação de dissuasão de abuso de anfetamina Download PDF

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Publication number
BR112019016208A2
BR112019016208A2 BR112019016208A BR112019016208A BR112019016208A2 BR 112019016208 A2 BR112019016208 A2 BR 112019016208A2 BR 112019016208 A BR112019016208 A BR 112019016208A BR 112019016208 A BR112019016208 A BR 112019016208A BR 112019016208 A2 BR112019016208 A2 BR 112019016208A2
Authority
BR
Brazil
Prior art keywords
formulation
abuse deterrence
amphetamine abuse
deterrence
amphetamine
Prior art date
Application number
BR112019016208A
Other languages
English (en)
Inventor
Baker David
Siner David
Ron Hanna
Daniely Yaron
Original Assignee
Vallon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vallon Pharmaceuticals Inc filed Critical Vallon Pharmaceuticals Inc
Publication of BR112019016208A2 publication Critical patent/BR112019016208A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

a presente invenção refere-se genericamente a formulações de dissuasão de abuso contendo sulfato de dextroanfetamina.
BR112019016208A 2017-02-06 2018-02-06 formulação de dissuasão de abuso de anfetamina BR112019016208A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762455227P 2017-02-06 2017-02-06
US15/591,677 US9931303B1 (en) 2017-02-06 2017-05-10 Abuse deterrent formulations of amphetamine
PCT/US2018/017019 WO2018145071A1 (en) 2017-02-06 2018-02-06 Abuse deterrent formulations of amphetamine

Publications (1)

Publication Number Publication Date
BR112019016208A2 true BR112019016208A2 (pt) 2020-04-14

Family

ID=61724997

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019016208A BR112019016208A2 (pt) 2017-02-06 2018-02-06 formulação de dissuasão de abuso de anfetamina

Country Status (14)

Country Link
US (3) US9931303B1 (pt)
EP (2) EP3576719B8 (pt)
JP (2) JP7054709B2 (pt)
CN (1) CN110461309A (pt)
AU (1) AU2018215669B2 (pt)
BR (1) BR112019016208A2 (pt)
CA (1) CA3088959A1 (pt)
DK (2) DK3576719T3 (pt)
EA (1) EA039416B1 (pt)
ES (1) ES2890862T3 (pt)
IL (1) IL268367A (pt)
PL (1) PL3576719T3 (pt)
PT (1) PT3576719T (pt)
WO (1) WO2018145071A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9931303B1 (en) * 2017-02-06 2018-04-03 Alcobra Ltd. Abuse deterrent formulations of amphetamine
EP3473246A1 (en) * 2017-10-19 2019-04-24 Capsugel Belgium NV Immediate release abuse deterrent formulations
GB201809976D0 (en) * 2018-06-18 2018-08-01 Neurocentrx Pharma Ltd Novel formulations
US11253490B1 (en) * 2021-05-17 2022-02-22 Vallon Pharamaceuticals, Inc. Compositions and methods of treating cognitive impairment
WO2023212247A1 (en) * 2022-04-27 2023-11-02 Aardvark Therapeutics, Inc. Improved abuse-deterrent pharmaceutical composition with aversion properties

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700561B2 (en) 2002-02-22 2010-04-20 Shire Llc Abuse-resistant amphetamine prodrugs
GB0506982D0 (en) 2005-04-06 2005-05-11 Mw Encap Ltd Abuse resistant capsules
CN101193650A (zh) * 2005-04-08 2008-06-04 新河药品股份有限公司 抗滥用的苯丙胺前体药物
JP2010260812A (ja) 2009-05-01 2010-11-18 Nakanihon Capsule Co Ltd ソフトカプセル
CN103608004A (zh) 2011-03-23 2014-02-26 艾伦索尔医药发展股份有限公司 用于治疗注意力缺陷障碍的方法和组合物
FR2983409B1 (fr) 2011-12-06 2013-12-27 Ethypharm Sa Comprime susceptible de lutter contre le detournement par voie injectable
WO2013158810A1 (en) 2012-04-18 2013-10-24 Mallinckrodt Llc Immediate release pharmaceutical compositions with abuse deterrent properties
US10420729B2 (en) 2013-03-15 2019-09-24 R.P. Scherer Technologies, Llc Abuse resistant capsule
CA2817728A1 (en) * 2013-05-31 2014-11-30 Pharmascience Inc. Abuse deterrent immediate release formulation
US10744131B2 (en) * 2013-12-31 2020-08-18 Kashiv Biosciences, Llc Abuse-resistant drug formulations
JP6701168B2 (ja) * 2014-07-31 2020-05-27 コーニング インコーポレイテッド 熱強化ガラス、ならびにガラスの熱強化のための方法および装置
US9931303B1 (en) 2017-02-06 2018-04-03 Alcobra Ltd. Abuse deterrent formulations of amphetamine

Also Published As

Publication number Publication date
JP2020506238A (ja) 2020-02-27
EP3576719B8 (en) 2022-07-13
DK3576719T3 (da) 2021-10-04
EA201991863A1 (ru) 2020-02-17
IL268367A (en) 2019-09-26
EP3576719A1 (en) 2019-12-11
EA039416B1 (ru) 2022-01-25
EP3943066A1 (en) 2022-01-26
PT3576719T (pt) 2021-09-24
US11517537B2 (en) 2022-12-06
US20200085752A1 (en) 2020-03-19
JP7054709B2 (ja) 2022-04-14
WO2018145071A1 (en) 2018-08-09
PL3576719T3 (pl) 2022-01-03
AU2018215669A1 (en) 2019-09-19
JP2022091951A (ja) 2022-06-21
AU2018215669B2 (en) 2024-02-29
US20190076367A1 (en) 2019-03-14
US10471015B2 (en) 2019-11-12
EP3943066B1 (en) 2022-11-23
CA3088959A1 (en) 2018-08-09
EP3576719B1 (en) 2021-07-07
CN110461309A (zh) 2019-11-15
DK3943066T3 (da) 2023-02-20
ES2890862T3 (es) 2022-01-24
US9931303B1 (en) 2018-04-03

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements