WO2018115877A3 - Rumen derived antimicrobial peptides - Google Patents

Rumen derived antimicrobial peptides Download PDF

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Publication number
WO2018115877A3
WO2018115877A3 PCT/GB2017/053847 GB2017053847W WO2018115877A3 WO 2018115877 A3 WO2018115877 A3 WO 2018115877A3 GB 2017053847 W GB2017053847 W GB 2017053847W WO 2018115877 A3 WO2018115877 A3 WO 2018115877A3
Authority
WO
WIPO (PCT)
Prior art keywords
antimicrobial peptides
derived antimicrobial
rumen
rumen derived
peptides
Prior art date
Application number
PCT/GB2017/053847
Other languages
French (fr)
Other versions
WO2018115877A2 (en
Inventor
Sharon Ann HUWS
Linda OYAMA
Original Assignee
Aberystwyth University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aberystwyth University filed Critical Aberystwyth University
Publication of WO2018115877A2 publication Critical patent/WO2018115877A2/en
Publication of WO2018115877A3 publication Critical patent/WO2018115877A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a composition comprising rumen microbe derived peptides which have particular uses as antimicrobial agents.
PCT/GB2017/053847 2016-12-20 2017-12-20 Compositions and methods of treatment WO2018115877A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1621737.4A GB201621737D0 (en) 2016-12-20 2016-12-20 Compositions and methods of treatment
GB1621737.4 2016-12-20

Publications (2)

Publication Number Publication Date
WO2018115877A2 WO2018115877A2 (en) 2018-06-28
WO2018115877A3 true WO2018115877A3 (en) 2018-08-02

Family

ID=58284277

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2017/053847 WO2018115877A2 (en) 2016-12-20 2017-12-20 Compositions and methods of treatment

Country Status (2)

Country Link
GB (1) GB201621737D0 (en)
WO (1) WO2018115877A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111387133B (en) * 2020-02-25 2021-04-16 中国农业大学 Method for establishing model for inhibiting mouse mastitis by using Klebsiella pneumoniae bacteriophage
IT202100007214A1 (en) * 2021-03-24 2022-09-24 Softmining S R L PEPTIDE WITH ANTIMICROBIAL ACTIVITY
IT202100007211A1 (en) * 2021-03-24 2022-09-24 Softmining S R L PEPTIDE WITH ANTIMICROBIAL ACTIVITY

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ANALICE C. AZEVEDO ET AL: "ABSTRACT", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 81, no. 20, 15 October 2015 (2015-10-15), pages 7290 - 7304, XP055451410, ISSN: 0099-2240, DOI: 10.1128/AEM.01223-15 *
LINDA B. OYAMA ET AL: "Buwchitin: A Ruminal Peptide with Antimicrobial Potential against Enterococcus faecalis", FRONTIERS IN CHEMISTRY, vol. 5, 12 July 2017 (2017-07-12), XP055451352, DOI: 10.3389/fchem.2017.00051 *
LINDA B. OYAMA ET AL: "The rumen microbiome: an underexplored resource for novel antimicrobial discovery", NPJ BIOFILMS AND MICROBIOMES, vol. 3, no. 1, 1 December 2017 (2017-12-01), XP055451361, DOI: 10.1038/s41522-017-0042-1 *
OYAMA ET AL.: "Broad spectrumantimicrobial peptides derived froma bovine rumen", SOCIETY FOR GENERAL MICROBIOLOGY, ANNUAL CONFERENCE 2015, 30 March 2015 (2015-03-30), BIRMINGHAM, pages 1, 12, XP002778279 *
OYAMA ET AL.: "Broad-spectrum antimicrobial peptidesderived from a bovine rumen", SOCIETY FOR GENERAL MICROBIOLOGY, ANNUAL CONFERENCE 2015, 30 March 2015 (2015-03-30), BIRMINGHAM, pages 1, 124, XP002778280 *
OYAMA ET AL: "Prospecting Rumen Bacteria for Novel Antimicrobials", PHD THESIS, ABERYSTWYTH UNIVERSITY, UK, 1 January 2015 (2015-01-01), pages 1 - 302, XP009503502, Retrieved from the Internet <URL:http://hdl.handle.net/2160/43571> *
RAVI KUMAR K ET AL: "Partial purification of bacteriocin like substance from rumen liquor obtained from the slaughtered cattle for medical applications", ASIAN JOURNAL OF PHARMACEUTICAL AND CLINICAL RESEARCH : AJPCR, INDORE, IN, vol. 6, no. SUPPL.5, 1 October 2013 (2013-10-01), pages 180 - 183, XP009503505, ISSN: 0974-2441 *

Also Published As

Publication number Publication date
GB201621737D0 (en) 2017-02-01
WO2018115877A2 (en) 2018-06-28

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