EA201792366A1 - Способ разделения белка и прочих примесей и капсульных полисахаридов микроорганизмов - Google Patents

Способ разделения белка и прочих примесей и капсульных полисахаридов микроорганизмов

Info

Publication number
EA201792366A1
EA201792366A1 EA201792366A EA201792366A EA201792366A1 EA 201792366 A1 EA201792366 A1 EA 201792366A1 EA 201792366 A EA201792366 A EA 201792366A EA 201792366 A EA201792366 A EA 201792366A EA 201792366 A1 EA201792366 A1 EA 201792366A1
Authority
EA
Eurasian Patent Office
Prior art keywords
microorganisms
impurities
protein
capsular polysaccharides
separation
Prior art date
Application number
EA201792366A
Other languages
English (en)
Inventor
Рамеш Венкат Матур
Вивек Бабу Кандималла
Нарендер Дев Мантена
Махима Датла
Мутхиала Венкатесвара Редди
Кантан Кхаран
Original Assignee
Байолоджикал И Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байолоджикал И Лимитед filed Critical Байолоджикал И Лимитед
Publication of EA201792366A1 publication Critical patent/EA201792366A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Изобретение относится к способу отделения белка и прочих примесей от капсульных полисахаридов микроорганизмов. Более конкретно, настоящее изобретение относится к выделению капсульных полисахаридов микроорганизмов в чистой форме после удаления белка и прочих примесей.
EA201792366A 2015-04-28 2016-04-25 Способ разделения белка и прочих примесей и капсульных полисахаридов микроорганизмов EA201792366A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2161CH2015 2015-04-28
PCT/IN2016/000107 WO2016174683A1 (en) 2015-04-28 2016-04-25 Method for separation of protein and other impurities from microbial capsular polysaccharides

Publications (1)

Publication Number Publication Date
EA201792366A1 true EA201792366A1 (ru) 2018-03-30

Family

ID=56137482

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201792366A EA201792366A1 (ru) 2015-04-28 2016-04-25 Способ разделения белка и прочих примесей и капсульных полисахаридов микроорганизмов

Country Status (12)

Country Link
US (2) US10836839B2 (ru)
EP (1) EP3288983A1 (ru)
JP (1) JP6882193B2 (ru)
CN (1) CN107835821B (ru)
AU (1) AU2016254693B2 (ru)
BR (1) BR112017023437B1 (ru)
CA (1) CA2983708C (ru)
EA (1) EA201792366A1 (ru)
MX (1) MX2017013855A (ru)
SA (1) SA517390202B1 (ru)
WO (1) WO2016174683A1 (ru)
ZA (1) ZA201707454B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109890413B (zh) 2016-09-02 2024-04-16 赛诺菲巴斯德股份有限公司 脑膜炎奈瑟氏菌疫苗
EP3518965A1 (en) 2016-09-30 2019-08-07 Biological E Limited Multivalent pneumococcal vaccine compositions comprising polysaccharide-protein conjugates
WO2018104889A1 (en) * 2016-12-06 2018-06-14 Glaxosmithkline Biologicals Sa Purification process for capsular polysaccharide
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
CN114450576A (zh) 2019-10-01 2022-05-06 生物E有限公司 碳水化合物定量的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242501A (en) 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
CA2059693C (en) 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US5714354A (en) 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
ATE421339T1 (de) 1998-02-05 2009-02-15 Jackson H M Found Military Med Vereinfachte methode zur entfernung von freiem protein während der herstellung von protein- polysaccharid-konjugaten und impfstoffen unter verwendung von medien mit limitierter durchlässigkeit
GB0502096D0 (en) 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
BRPI0713215A2 (pt) * 2006-07-06 2012-04-17 Realince Life Sciences Pvt Ltd processo eficiente de produção e purificação de ácido hialurÈnico de elevado peso molecular e produto resultante
PT2074221E (pt) 2006-10-10 2010-09-06 Wyeth Llc Métodos melhorados para a separação de polissacáridos tipo 3 de streptococcus pneumoniae
HUE048398T2 (hu) * 2010-06-04 2020-07-28 Wyeth Llc Vakcinakészítmények
JP5944480B2 (ja) 2011-03-22 2016-07-05 セルム・インスティテュート・オブ・インディア・ピーブイティー．・リミテッド 多糖を調製するための新規な方法
CN103623401A (zh) 2012-08-23 2014-03-12 北京科兴中维生物技术有限公司 多价肺炎球菌荚膜多糖-蛋白质共轭组合物及其制备方法
EP3096785B1 (en) * 2014-01-21 2020-09-09 Pfizer Inc Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof

Also Published As

Publication number Publication date
US20210017300A1 (en) 2021-01-21
AU2016254693A1 (en) 2017-11-09
JP6882193B2 (ja) 2021-06-02
BR112017023437A2 (pt) 2018-07-31
JP2018514624A (ja) 2018-06-07
AU2016254693B2 (en) 2020-07-09
US11680111B2 (en) 2023-06-20
CA2983708C (en) 2023-09-19
CN107835821A (zh) 2018-03-23
WO2016174683A1 (en) 2016-11-03
US20180155453A1 (en) 2018-06-07
MX2017013855A (es) 2018-03-15
SA517390202B1 (ar) 2021-04-19
CN107835821B (zh) 2022-01-28
EP3288983A1 (en) 2018-03-07
US10836839B2 (en) 2020-11-17
CA2983708A1 (en) 2016-11-03
BR112017023437B1 (pt) 2022-03-22
ZA201707454B (en) 2019-11-27

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