EA201490092A1 - Кристаллы конденсированного гетероциклического соединения - Google Patents

Кристаллы конденсированного гетероциклического соединения

Info

Publication number
EA201490092A1
EA201490092A1 EA201490092A EA201490092A EA201490092A1 EA 201490092 A1 EA201490092 A1 EA 201490092A1 EA 201490092 A EA201490092 A EA 201490092A EA 201490092 A EA201490092 A EA 201490092A EA 201490092 A1 EA201490092 A1 EA 201490092A1
Authority
EA
Eurasian Patent Office
Prior art keywords
crystals
heterocyclic compound
condensed heterocyclic
imidazo
pyridin
Prior art date
Application number
EA201490092A
Other languages
English (en)
Other versions
EA026137B1 (ru
Inventor
Кацухико Ямамото
Original Assignee
Такеда Фармасьютикал Компани Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Такеда Фармасьютикал Компани Лимитед filed Critical Такеда Фармасьютикал Компани Лимитед
Publication of EA201490092A1 publication Critical patent/EA201490092A1/ru
Publication of EA026137B1 publication Critical patent/EA026137B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

Настоящее изобретение относится к кристаллам 1-этил-7-метил-3-{4-[(3-метил-3H-имидазо[4,5-b]пиридин-2-ил)окси]фенил}-1,3-дигидро-2Н-имидазо[4,5-b]пиридин-2-она, пригодным в качестве профилактического или терапевтического агента при шизофрении и тому подобное, которые характеризуются порошковой дифракционной рентгенограммой, имеющей характерные пики на межплоскостных расстояниях (d) 13,59 плюс или минус 0,2 и 6,76 плюс или минус 0,2 Ангстрема при дифракции рентгеновского излучения на порошках.
EA201490092A 2011-06-22 2012-06-21 Кристаллы конденсированного гетероциклического соединения EA026137B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011138920 2011-06-22
PCT/JP2012/066461 WO2012176934A1 (en) 2011-06-22 2012-06-21 Crystal of fused heterocyclic compound

Publications (2)

Publication Number Publication Date
EA201490092A1 true EA201490092A1 (ru) 2014-05-30
EA026137B1 EA026137B1 (ru) 2017-03-31

Family

ID=46551819

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201490092A EA026137B1 (ru) 2011-06-22 2012-06-21 Кристаллы конденсированного гетероциклического соединения

Country Status (26)

Country Link
US (1) US9512118B2 (ru)
EP (1) EP2723738B1 (ru)
JP (1) JP6025757B2 (ru)
KR (1) KR20140040777A (ru)
CN (1) CN103608348B (ru)
AR (1) AR087004A1 (ru)
AU (1) AU2012274292B2 (ru)
BR (1) BR112013032052A2 (ru)
CA (1) CA2839825C (ru)
CL (1) CL2013003632A1 (ru)
CO (1) CO6862150A2 (ru)
CR (1) CR20140033A (ru)
DO (1) DOP2013000311A (ru)
EA (1) EA026137B1 (ru)
EC (1) ECSP14013165A (ru)
GE (1) GEP20166475B (ru)
MA (1) MA35274B1 (ru)
MX (1) MX342990B (ru)
MY (1) MY163483A (ru)
PE (1) PE20141030A1 (ru)
TN (1) TN2013000510A1 (ru)
TW (1) TWI570122B (ru)
UA (1) UA112082C2 (ru)
UY (1) UY34150A (ru)
WO (1) WO2012176934A1 (ru)
ZA (1) ZA201309611B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5973990B2 (ja) * 2011-03-16 2016-08-23 武田薬品工業株式会社 縮合複素環化合物
US10851076B2 (en) 2017-08-10 2020-12-01 Pratt Bethers Method for purifying crystals using solvent vapors
US10960322B2 (en) 2018-07-02 2021-03-30 Pratt Bethers Apparatus for purifying crystals using solvent vapors
US10308626B1 (en) 2018-07-02 2019-06-04 Pratt Bethers Crystal purification in a glass or metal container
US20240052227A1 (en) * 2022-08-12 2024-02-15 Raytheon Company Water-based polymer network for transpirant cooling applications

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5597826A (en) * 1994-09-14 1997-01-28 Pfizer Inc. Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist
CA2582479C (en) * 2004-10-07 2011-07-12 Pfizer Products Inc. Benzoimidazole derivatives useful as antiproliferative agents
AU2006285915B2 (en) 2005-08-30 2011-02-24 Asahi Kasei Pharma Corporation Sulfonamide compound
FI20055498A0 (fi) 2005-09-16 2005-09-16 Biotie Therapies Corp Sulfonamidijohdannaisia
US7618982B2 (en) 2005-12-19 2009-11-17 Nerviano Medical Sciences S.R.L. Heteroarylpyrrolopyridinones active as kinase inhibitors
CN101384583A (zh) * 2006-02-15 2009-03-11 塞诺菲-安万特股份有限公司 氮杂环基-取代的芳基二氢异喹啉酮、它们的制备方法和它们作为药物的用途
US20080090834A1 (en) 2006-07-06 2008-04-17 Pfizer Inc Selective azole pde10a inhibitor compounds
JP5313883B2 (ja) 2007-04-18 2013-10-09 キッセイ薬品工業株式会社 含窒素縮合環誘導体、それを含有する医薬組成物及びその医薬用途
CA2717529A1 (en) 2008-03-11 2009-09-17 Cellzome Limited Sulfonamides as zap-70 inhibitors
TW201030001A (en) 2008-11-14 2010-08-16 Amgen Inc Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors
TWI396689B (zh) 2008-11-14 2013-05-21 Amgen Inc 作為磷酸二酯酶１０抑制劑之吡衍生物
WO2010126002A1 (ja) 2009-04-28 2010-11-04 塩野義製薬株式会社 ヘテロ環スルホンアミド化合物を含有する医薬
MY165585A (en) 2010-06-24 2018-04-05 Takeda Pharmaceuticals Co Fused heterocyclic compounds as phosphodiesterases (pdes) inhibitors
US9029536B2 (en) 2010-08-04 2015-05-12 Takeda Pharmaceutical Company Limited Fused heterocyclic compounds
EP2604597B1 (en) 2010-08-10 2017-01-04 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof inhibitor of phosphodiesterase 10a
JP5973990B2 (ja) 2011-03-16 2016-08-23 武田薬品工業株式会社 縮合複素環化合物

Also Published As

Publication number Publication date
EA026137B1 (ru) 2017-03-31
GEP20166475B (en) 2016-05-10
JP2014516918A (ja) 2014-07-17
KR20140040777A (ko) 2014-04-03
EP2723738A1 (en) 2014-04-30
ZA201309611B (en) 2014-08-27
MY163483A (en) 2017-09-15
CR20140033A (es) 2014-03-12
UA112082C2 (uk) 2016-07-25
MX342990B (es) 2016-10-20
BR112013032052A2 (pt) 2016-12-13
CN103608348A (zh) 2014-02-26
TN2013000510A1 (en) 2015-03-30
ECSP14013165A (es) 2014-02-28
PE20141030A1 (es) 2014-08-29
EP2723738B1 (en) 2018-03-14
AU2012274292B2 (en) 2016-10-27
AR087004A1 (es) 2014-02-05
CA2839825C (en) 2019-04-09
CO6862150A2 (es) 2014-02-10
MX2013015354A (es) 2014-02-11
UY34150A (es) 2013-01-31
WO2012176934A1 (en) 2012-12-27
TWI570122B (zh) 2017-02-11
NZ618944A (en) 2015-08-28
MA35274B1 (fr) 2014-07-03
US20140113932A1 (en) 2014-04-24
JP6025757B2 (ja) 2016-11-16
CL2013003632A1 (es) 2014-06-06
AU2012274292A1 (en) 2014-01-16
CA2839825A1 (en) 2012-12-27
TW201313709A (zh) 2013-04-01
CN103608348B (zh) 2016-03-30
US9512118B2 (en) 2016-12-06
DOP2013000311A (es) 2014-02-28

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM RU