EA201290026A1 - Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid) - Google Patents

Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid)

Info

Publication number
EA201290026A1
EA201290026A1 EA201290026A EA201290026A EA201290026A1 EA 201290026 A1 EA201290026 A1 EA 201290026A1 EA 201290026 A EA201290026 A EA 201290026A EA 201290026 A EA201290026 A EA 201290026A EA 201290026 A1 EA201290026 A1 EA 201290026A1
Authority
EA
Eurasian Patent Office
Prior art keywords
patient
risk
treating
analism
reception
Prior art date
Application number
EA201290026A
Other languages
English (en)
Russian (ru)
Inventor
Брайан Аулт
Клара Хуанг
Эверардус Орлеманс
Джон Р. Плачетка
Марк Состек
Original Assignee
Астразенека Аб
Поузен Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43381035&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201290026(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Астразенека Аб, Поузен Инк. filed Critical Астразенека Аб
Publication of EA201290026A1 publication Critical patent/EA201290026A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA201290026A 2009-06-25 2010-06-23 Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid) EA201290026A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22042009P 2009-06-25 2009-06-25
US22597009P 2009-07-16 2009-07-16
US31052510P 2010-03-04 2010-03-04
PCT/SE2010/050712 WO2010151216A1 (en) 2009-06-25 2010-06-23 Method for treating a patient at risk for developing an nsaid-associated ulcer

Publications (1)

Publication Number Publication Date
EA201290026A1 true EA201290026A1 (ru) 2012-07-30

Family

ID=43381035

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201290026A EA201290026A1 (ru) 2009-06-25 2010-06-23 Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid)

Country Status (13)

Country Link
US (3) US8945621B2 (enExample)
EP (1) EP2445499A4 (enExample)
JP (1) JP2012531409A (enExample)
KR (1) KR20120030106A (enExample)
CN (1) CN102481293A (enExample)
AU (1) AU2010263304A1 (enExample)
CA (1) CA2764963C (enExample)
EA (1) EA201290026A1 (enExample)
IL (1) IL216877A0 (enExample)
MA (1) MA33553B1 (enExample)
MX (1) MX2011013467A (enExample)
SG (1) SG176724A1 (enExample)
WO (1) WO2010151216A1 (enExample)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
EA201100313A1 (ru) 2008-09-09 2011-10-31 Астразенека Аб Способ доставки фармацевтической композиции пациенту, нуждающемуся в этом
US8435545B2 (en) 2011-09-01 2013-05-07 Qualicaps, Inc. Capsule having broad color spectrum
US8420057B2 (en) 2011-09-01 2013-04-16 Qualicaps, Inc. Capsule having broad color spectrum
US9539214B2 (en) 2011-12-28 2017-01-10 Pozen Inc. Compositions and methods for delivery of omeprazole plus acetylsalicylic acid
US10653777B2 (en) 2015-02-10 2020-05-19 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10537642B1 (en) 2015-02-10 2020-01-21 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10799588B2 (en) 2015-02-10 2020-10-13 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11110173B2 (en) 2015-02-10 2021-09-07 Axsome Therapeutics, Inc Pharmaceutical compositions comprising meloxicam
US11607456B2 (en) 2015-02-10 2023-03-21 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10729773B2 (en) 2015-02-10 2020-08-04 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10780165B2 (en) 2015-02-10 2020-09-22 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US12485176B2 (en) 2015-02-10 2025-12-02 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10695429B2 (en) 2015-02-10 2020-06-30 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11738085B2 (en) 2015-02-10 2023-08-29 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10758618B2 (en) 2015-02-10 2020-09-01 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10058614B2 (en) 2015-02-10 2018-08-28 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10512692B2 (en) 2015-02-10 2019-12-24 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10532101B1 (en) 2015-02-10 2020-01-14 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11045549B2 (en) 2015-02-10 2021-06-29 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11013805B2 (en) 2015-02-10 2021-05-25 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10821181B2 (en) 2015-02-10 2020-11-03 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11013806B2 (en) 2015-02-10 2021-05-25 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10933136B2 (en) 2015-02-10 2021-03-02 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10729774B1 (en) 2015-02-10 2020-08-04 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10780166B2 (en) 2015-02-10 2020-09-22 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10695430B2 (en) 2015-02-10 2020-06-30 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11602563B2 (en) 2015-02-10 2023-03-14 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10702602B2 (en) 2015-02-10 2020-07-07 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10933137B2 (en) 2015-02-10 2021-03-02 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10722583B2 (en) 2015-02-10 2020-07-28 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10517950B1 (en) 2015-02-10 2019-12-31 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11806354B2 (en) 2017-01-04 2023-11-07 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
RS61346B1 (sr) 2017-01-04 2021-02-26 Axsome Therapeutics Inc Farmaceutske kompozicije koje obuhvataju meloksikam i rizatriptan
US11617755B2 (en) 2017-01-04 2023-04-04 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10905693B2 (en) 2017-01-04 2021-02-02 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11433078B2 (en) 2017-01-04 2022-09-06 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10471014B2 (en) 2017-01-04 2019-11-12 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11471465B2 (en) 2017-01-04 2022-10-18 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11266657B2 (en) 2017-01-04 2022-03-08 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11433079B2 (en) 2017-01-04 2022-09-06 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11207327B2 (en) 2017-01-04 2021-12-28 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11801250B2 (en) 2017-01-04 2023-10-31 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10583144B2 (en) 2017-01-04 2020-03-10 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10821182B2 (en) 2017-06-29 2020-11-03 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10729697B2 (en) 2017-01-04 2020-08-04 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10940153B2 (en) 2017-01-04 2021-03-09 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10583088B2 (en) 2017-01-04 2020-03-10 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10894053B2 (en) 2017-01-04 2021-01-19 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10729696B2 (en) 2017-01-04 2020-08-04 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10561664B1 (en) 2017-01-04 2020-02-18 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10688185B2 (en) 2017-06-29 2020-06-23 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10512693B2 (en) 2017-06-29 2019-12-24 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10918722B2 (en) 2017-06-29 2021-02-16 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10987358B2 (en) 2017-06-29 2021-04-27 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11617756B2 (en) 2017-06-29 2023-04-04 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11759522B2 (en) 2017-06-29 2023-09-19 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11219626B2 (en) 2017-06-29 2022-01-11 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11617791B2 (en) 2017-06-29 2023-04-04 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10688102B2 (en) 2017-06-29 2020-06-23 Axsome Therapeutics, Inc. Combination treatment for migraine and other pain
US11510927B2 (en) 2017-06-29 2022-11-29 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US11865117B2 (en) 2017-06-29 2024-01-09 Axsome Therapeutics, Inc Pharmaceutical compositions comprising meloxicam
US11185550B2 (en) 2017-06-29 2021-11-30 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US10758617B2 (en) 2017-06-29 2020-09-01 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
EP3999013A4 (en) * 2019-07-15 2023-07-26 R.P. Scherer Technologies, LLC SOFT GEL CAPSULE WITH ENTERIC PROTON PUMP INHIBITOR
US20240058354A1 (en) 2020-04-06 2024-02-22 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US12128052B2 (en) 2020-05-28 2024-10-29 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US20250319071A1 (en) * 2020-12-30 2025-10-16 Hk Inno.N Corporation Pharmaceutical composition comprising tegoprazan and non-steroidal anti-inflammatory drugs
US12370196B2 (en) 2020-12-31 2025-07-29 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
AU2021414212A1 (en) 2020-12-31 2023-07-20 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US12005118B2 (en) 2022-05-19 2024-06-11 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
WO2025207796A1 (en) * 2024-03-26 2025-10-02 The Medical College Of Wisconsin, Inc. Methods and compositions for treatment of peptic ulcers and/or peptic ulcer disease

Family Cites Families (232)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
DE2950977A1 (de) 1978-12-22 1980-07-10 Donald E Panoz Neue galenische zubereitungsform fuer die orale verabreichung von medikamenten mit programmierter besetzung, sowie verfahren zu ihrer herstellung
US4198390A (en) 1979-01-31 1980-04-15 Rider Joseph A Simethicone antacid tablet
FR2470599A1 (fr) 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
US4344929A (en) 1980-04-25 1982-08-17 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
CY1398A (en) 1981-09-04 1987-12-18 Glaxo Group Ltd Pharmaceutical compositions containing non-steroidal anti-inflammatory agents
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
JPS59227870A (ja) 1983-06-07 1984-12-21 Yamanouchi Pharmaceut Co Ltd 新規２−グアニジノチアゾリン誘導体ならびにその製造法
US4554276A (en) 1983-10-03 1985-11-19 Pfizer Inc. 2-Amino-5-hydroxy-4-methylpyrimidine derivatives
US4522826A (en) 1984-02-08 1985-06-11 Richardson-Vicks Inc. Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same
US4552899A (en) 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
IL75400A (en) 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
IT1196190B (it) 1984-07-12 1988-11-10 Lisapharma Spa Forma farmaceutica solida orale ad azione sequenziale per la somministrazione di farmaci ad effetto collaterale ulcerogeno
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU4640985A (en) 1984-08-31 1986-03-06 Nippon Chemiphar Co. Ltd. Benzimidazole derivatives
US4766117A (en) 1984-10-11 1988-08-23 Pfizer Inc. Antiinflammatory compositions and methods
US4676984A (en) 1985-08-14 1987-06-30 American Home Products Corp. Rehydratable antacid composition
US4704278A (en) 1984-10-17 1987-11-03 American Home Products Corp (Del) Fluidized magaldrate suspension
DE3603576A1 (de) 1986-02-06 1987-08-13 Code Kaffee Handel Verwendung von gerbstoffen und/oder chlorogensaeure sowie nahrungs-, genuss- und/oder arzneimittel mit gerbstoff- und/oder chlorogensaeurezusatz
CA1327010C (en) 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
US4965065A (en) 1986-04-29 1990-10-23 Bristol-Myers Squibb Company Gastroprotective process and compositions
US4757060A (en) 1986-03-04 1988-07-12 Bristol-Myers Company Non-steroidal anti-inflammatory compositions protected against gastrointestinal injury with a combination of certain H1 and H2, receptor blockers
US5043358A (en) 1986-03-04 1991-08-27 Bristol-Myers Squibb Company Gastroprotective process
US5037815A (en) 1986-03-04 1991-08-06 Bristol-Myers Squibb Co. Non-steroidal anti-inflammatory compositions protected against gastrointestinal injury with a combination of certain H1 - and H2 -receptor blockers
GB2189699A (en) 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
US5260333A (en) 1986-08-08 1993-11-09 Bristol Myers Squibb Company Effect of a combination of a terbutaline, diphenhydramine and ranitidine composition on gastrointestinal injury produced by nonsteroidal anti-inflammatory compositions
US5026560A (en) 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
EP0320550A1 (en) 1987-12-18 1989-06-21 Bristol-Myers Company Non steroidal anti-inflammatory drug composition containing H1 blockers, H2 blockers, beta adrenergic agonists or combinations thereof and an alkalizing agent
GB8805268D0 (en) 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
JPH0768125B2 (ja) 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤
SE8804629D0 (sv) 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
US4948581A (en) 1989-02-17 1990-08-14 Dojin Iyaku-Kako Co., Ltd. Long acting diclofenac sodium preparation
NZ235877A (en) 1989-11-02 1992-09-25 Mcneil Ppc Inc Composition comprising acetaminophen or nsaid and an h 1 or h 2 receptor blocker and/or proton pump inhibitor for treating overindulgence
US5204118A (en) 1989-11-02 1993-04-20 Mcneil-Ppc, Inc. Pharmaceutical compositions and methods for treating the symptoms of overindulgence
EP0527887B1 (en) 1990-05-03 1995-04-26 G.D. Searle & Co. Pharmaceutical composition
AU8089091A (en) 1990-05-03 1991-11-27 G.D. Searle & Co. Pharmaceutical composition containing ibuprofen and a prostaglandin
WO1991016896A1 (en) 1990-05-03 1991-11-14 G.D. Searle & Co. Pharmaceutical composition for use in treating pain
JP3049367B2 (ja) 1990-06-20 2000-06-05 アストラゼネカ・アクチエボラーグ ジアルコキシ−ピリジニル−ベンズイミダゾール誘導体、その製造方法およびそれを含む医薬
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
DE4035455A1 (de) 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
CA2104684A1 (en) 1991-03-04 1992-09-05 Mahdi B. Fawzi Salts/ion pairs of non-steroidal anti-inflammatory drugs in various dosage forms
US5409709A (en) 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen
ES2130152T3 (es) 1991-12-06 1999-07-01 Glaxo Group Ltd Medicamentos para tratar dolencias inflamatorias o para analgesia que contienen un nsaid y ranitidina/citrato de bismuto.
JP3802555B2 (ja) 1991-12-17 2006-07-26 フイズ テクノロジーズ リミテッド 潰瘍予防及び治療組成物並びに方法
WO1993012817A1 (en) 1991-12-20 1993-07-08 Warner-Lambert Company Therapeutic combinations useful in the treatment of gastroesophageal reflux disease
US5294433A (en) 1992-04-15 1994-03-15 The Procter & Gamble Company Use of H-2 antagonists for treatment of gingivitis
GR1002332B (el) 1992-05-21 1996-05-16 Mcneil-Ppc Inc. Νεες φαρμακευτικες συνθεσεις που περιεχουν σιμεθεικονη.
EP0663839A4 (en) 1992-09-29 1998-06-03 Merck & Co Inc Ibuprofen-h 2? antagonist combinations.
CA2110313C (en) 1992-12-01 2004-10-26 Edward John Roche Pharmaceutical compositions containing a guanidinothiazole compound and antacids
US5686105A (en) 1993-10-19 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
SE9301830D0 (sv) 1993-05-28 1993-05-28 Ab Astra New compounds
DK66493D0 (da) 1993-06-08 1993-06-08 Ferring A S Praeparater, isaer til brug ved behandling af inflammatoriske tarmsygdomme eller til at opnaa forbedret saarheling
SE9302395D0 (sv) 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
SE9302396D0 (sv) 1993-07-09 1993-07-09 Ab Astra A novel compound form
WO1995011024A1 (en) 1993-10-19 1995-04-27 The Procter & Gamble Company Picosulphate dosage form
US5514663A (en) 1993-10-19 1996-05-07 The Procter & Gamble Company Senna dosage form
US6025395A (en) 1994-04-15 2000-02-15 Duke University Method of preventing or delaying the onset and progression of Alzheimer's disease and related disorders
US5643960A (en) 1994-04-15 1997-07-01 Duke University Method of delaying onset of alzheimer's disease symptoms
FR2719999B1 (fr) 1994-05-17 1996-08-02 Georges Serge Grimberg Composition pharmaceutique à base de gomme de guar et d'un antiacide neutralisant, à laquelle peut être ajoutée une série de principes actifs thérapeutiques.
TNSN95062A1 (fr) 1994-05-27 1996-02-06 Astra Ab Nouveaux derives dialkoxy-pyridinyle-benzimidazole
MX9600857A (es) 1994-07-08 1997-06-28 Astra Ab Forma de dosificacion i en tabletas, con unidades multiples.
US5702723A (en) 1994-08-02 1997-12-30 Griffin; David Multi-stage delivery system for ingestible medications or nutrients
WO1996005199A1 (de) 1994-08-12 1996-02-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazopyridinsalz
CN1102144C (zh) 1994-08-13 2003-02-26 株式会社柳韩洋行 新的嘧啶衍生物及其制备方法
ZA959469B (en) 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
DE69621773T2 (de) 1995-01-27 2003-01-02 Board Of Regents, The University Of Texas System Verfahren zur erhöhung der therapeutischen wirkung von nsaids und dazu verwendbare zwitterionische phospholipidhaltige zusammensetungen
SE9500422D0 (sv) 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
SE9500478D0 (sv) 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US5955451A (en) 1995-05-12 1999-09-21 The University Of Texas System Board Of Regents Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein
US6132768A (en) 1995-07-05 2000-10-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors
US6031549A (en) * 1995-07-19 2000-02-29 Extempo Systems, Inc. System and method for directed improvisation by computer controlled characters
CA2231550A1 (en) 1995-09-27 1997-04-03 Merck Frosst Canada Inc. Compositions for treating inflammation containing certain prostaglandins and a selective cyclooxygenase-2 inhibitor
US5880731A (en) * 1995-12-14 1999-03-09 Microsoft Corporation Use of avatars with automatic gesturing and bounded interaction in on-line chat session
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US20050054682A1 (en) 1996-01-04 2005-03-10 Phillips Jeffrey O. Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE9600072D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients II
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
SE9600071D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients I
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
US5872145A (en) * 1996-08-16 1999-02-16 Pozen, Inc. Formulation of 5-HT agonist and NSAID for treatment of migraine
US8022095B2 (en) 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US6077539A (en) * 1996-11-12 2000-06-20 Pozen, Inc. Treatment of migraine headache
CA2271799A1 (en) 1996-11-22 1998-05-28 The Procter & Gamble Company Compositions for the treatment of gastrointestinal disorders containing bismuth, and nsaid and one or more antimicrobials
CA2271381A1 (en) 1996-11-22 1998-05-28 Owen Rickford Carryl Compositions for the treatment of gastrointestinal disorders containing bismuth and nsaid
SE510666C2 (sv) 1996-12-20 1999-06-14 Astra Ab Nya Kristallmodifikationer
US6160020A (en) 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen
SE510650C2 (sv) 1997-05-30 1999-06-14 Astra Ab Ny förening
SE510643C2 (sv) 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
JP2001515854A (ja) 1997-09-11 2001-09-25 ニュコメデ ダンマルク アクティーゼルスカブ 非ステロイド性抗炎症薬物質（ＮＳＡＩＤｓ）の改良された開放性多重−単位組成物
JP2001521910A (ja) 1997-10-31 2001-11-13 モンサント カンパニー ゲランガム錠剤コーティング
ES2216351T3 (es) 1997-12-08 2004-10-16 Altana Pharma Ag Nueva forma de supositorio que comprende un compuesto activo labil o acidos.
SE9704870D0 (sv) 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I
FR2772615B1 (fr) 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
DE19801811B4 (de) 1998-01-19 2004-12-23 Stada Arzneimittel Ag Pharmazeutische Zubereitung zur oralen Verabreichung
AU2481899A (en) 1998-01-30 1999-08-16 Sepracor, Inc. S-lansoprazole compositions and methods
CA2320963A1 (en) 1998-01-30 1999-08-05 Sepracor, Inc. R-lansoprazole compositions and methods
US6350470B1 (en) 1998-04-29 2002-02-26 Cima Labs Inc. Effervescent drug delivery system for oral administration
GB9814215D0 (en) 1998-07-01 1998-09-02 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
US6093734A (en) 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
TR200100708T2 (tr) 1998-09-10 2001-07-23 Nycomed Danmark A/S İlaç maddelerine mahsus çabuk salımlı farmasötik bileşimler.
US8231899B2 (en) 1998-09-10 2012-07-31 Nycomed Danmark Aps Quick release pharmaceutical compositions of drug substances
US6387410B1 (en) 1998-09-10 2002-05-14 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
US20020090395A1 (en) 1998-09-10 2002-07-11 Austen John Woolfe Anti-inflammatory pharmaceutical formulations
EP1117386B1 (en) 1998-09-28 2004-12-01 Warner-Lambert Company Enteric and colonic delivery using hpmc capsules
US6389458B2 (en) * 1998-10-30 2002-05-14 Ideaflood, Inc. Method, apparatus and system for directing access to content on a computer network
US6485747B1 (en) 1998-10-30 2002-11-26 Monsanto Company Coated active tablet(s)
SE9803772D0 (sv) 1998-11-05 1998-11-05 Astra Ab Pharmaceutical formulation
US6797283B1 (en) 1998-12-23 2004-09-28 Alza Corporation Gastric retention dosage form having multiple layers
DE19901687B4 (de) 1999-01-18 2006-06-01 Grünenthal GmbH Opioide Analgetika mit kontrollierter Wirkstofffreisetzung
US6183779B1 (en) 1999-03-22 2001-02-06 Pharmascience Inc. Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin
HRP20010780A2 (en) 1999-03-26 2002-12-31 Pozen Inc High potency dihydroergotamine compositions
US7546530B1 (en) * 1999-04-15 2009-06-09 Hoshiko Llc Method and apparatus for mapping a site on a wide area network
AU4198899A (en) 1999-05-20 2000-12-12 Par Pharmaceutical, Inc. Stabilized composition based on pyridinyl-sulfinyl-benzimidazoles and process
TWI243672B (en) 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
SE9902386D0 (sv) 1999-06-22 1999-06-22 Astra Ab New formulation
US6126816A (en) 1999-07-14 2000-10-03 Ruiz, Jr.; Reuben F. Wastewater treatment device
CA2277407A1 (en) 1999-07-14 2001-01-14 Bernard Charles Sherman Pharmaceutical tablet comprising an nsaid and misoprostol
US6687746B1 (en) * 1999-08-30 2004-02-03 Ideaflood, Inc. System apparatus and method for hosting and assigning domain names on a wide area network
GB9923436D0 (en) 1999-10-04 1999-12-08 American Home Prod Pharmaceutical compositions
US8291340B1 (en) * 1999-10-14 2012-10-16 Hoshiko Llc Method and apparatus for providing content to users
US6763379B1 (en) * 1999-10-14 2004-07-13 Ideaflood, Inc. System, apparatus and method for presenting and displaying content on a wide area network
US6787164B2 (en) 2000-02-23 2004-09-07 Bioselect Innovations, Inc. Composition and method for treating the effects of diseases and maladies
SE0000773D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
US6978252B2 (en) * 2000-04-18 2005-12-20 Ideaflood, Inc. Method and system for transacting with network traffic
US7370110B2 (en) * 2000-04-18 2008-05-06 Hoshiko Llc Method and system for operating a network server to discourage inappropriate use
US7593864B2 (en) * 2000-04-18 2009-09-22 Brian Mark Shuster Method and apparatus for managing ownership of virtual property
US6862610B2 (en) * 2000-05-08 2005-03-01 Ideaflood, Inc. Method and apparatus for verifying the identity of individuals
US7228327B2 (en) * 2000-05-08 2007-06-05 Hoshiko Llc Method and apparatus for delivering content via information retrieval devices
US20020019800A1 (en) * 2000-05-16 2002-02-14 Ideaflood, Inc. Method and apparatus for transacting divisible property
US7051362B2 (en) * 2000-05-16 2006-05-23 Ideaflood, Inc. Method and system for operating a network server to discourage inappropriate use
US7899703B2 (en) * 2000-05-16 2011-03-01 Brian Mark Shuster Method and apparatus for providing internet advertising service
US7428576B2 (en) * 2000-05-16 2008-09-23 Hoshiko Llc Addressee-defined mail addressing system and method
US7200863B2 (en) * 2000-05-16 2007-04-03 Hoshiko Llc System and method for serving content over a wide area network
US20020044962A1 (en) 2000-06-06 2002-04-18 Cherukuri S. Rao Encapsulation products for controlled or extended release
US20020022999A1 (en) * 2000-06-23 2002-02-21 Shuster Brian Mark Method and apparatus for providing audio advertisements in a computer network
SE0002476D0 (sv) 2000-06-30 2000-06-30 Astrazeneca Ab New compounds
US6756879B2 (en) * 2000-07-11 2004-06-29 Ideaflood, Inc. Method and apparatus for securing delivery of goods
US6826546B1 (en) * 2000-08-17 2004-11-30 Ideaflood, Inc. Method and system for licensing a copy of a copyright protected work
US6895236B2 (en) * 2000-08-23 2005-05-17 Ideaflood, Inc. Method for verifying geographical location of wide area network users
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
US7029701B2 (en) 2000-09-11 2006-04-18 Andrx Pharmaceuticals, Llc Composition for the treatment and prevention of ischemic events
US20020045184A1 (en) 2000-10-02 2002-04-18 Chih-Ming Chen Packaging system
US6749867B2 (en) 2000-11-29 2004-06-15 Joseph R. Robinson Delivery system for omeprazole and its salts
JP2004525897A (ja) 2001-02-14 2004-08-26 グラクソ、ウェルカム、ソシエダッド、アノニマ 医薬処方
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US7801944B2 (en) * 2001-05-18 2010-09-21 Gary Stephen Shuster Distributed computing using agent embedded in content unrelated to agents processing function
ES2348710T5 (es) * 2001-06-01 2014-02-17 Pozen, Inc. Composiciones farmacéuticas para el suministro coordinado de NSAID
US20100172983A1 (en) * 2001-06-01 2010-07-08 Plachetka John R Pharmaceutical Compositions for the Coordinated Delivery of Naproxen and Esomeprazole
US8206741B2 (en) * 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US20030068356A1 (en) 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
AR036354A1 (es) 2001-08-31 2004-09-01 Takeda Chemical Industries Ltd Preparacion solida
US6930099B2 (en) 2001-09-07 2005-08-16 Advanced Medical Instruments Composition for the treatment and prevention of endothelial dysfunction
US20040073439A1 (en) * 2002-03-26 2004-04-15 Ideaflood, Inc. Method and apparatus for issuing a non-transferable ticket
US7465229B2 (en) * 2002-03-26 2008-12-16 Hoshiko Llc Slot-machine game with adjusting payout table
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
FR2845917B1 (fr) 2002-10-21 2006-07-07 Negma Gild Composition pharmaceutique associant le tenatoprazole et un anti-inflammatoire
US20070243251A1 (en) 2002-12-20 2007-10-18 Rajneesh Taneja Dosage Forms Containing A PPI, NSAID, and Buffer
US20040131676A1 (en) 2002-12-20 2004-07-08 Rajneesh Taneja Dosage forms containing a PPI, NSAID, and buffer
US20040121004A1 (en) 2002-12-20 2004-06-24 Rajneesh Taneja Dosage forms containing a PPI, NSAID, and buffer
WO2004060355A1 (en) * 2002-12-26 2004-07-22 Pozen Inc. Multilayer Dosage Forms Containing NSAIDs and Triptans
WO2004062552A2 (en) 2003-01-09 2004-07-29 Galephar M/F Pharmaceutical composition containing a nsaid and a benzimidazole derivative
WO2004064815A1 (en) 2003-01-21 2004-08-05 Smartrix Technologies Inc. Oral dosage formulation
US8290948B2 (en) * 2003-06-30 2012-10-16 Hoshiko, Llc Method and apparatus for content filtering
US7835294B2 (en) * 2003-09-03 2010-11-16 Gary Stephen Shuster Message filtering method
JP2005145894A (ja) 2003-11-17 2005-06-09 Takeda Chem Ind Ltd 固形製剤
US20050163847A1 (en) 2004-01-21 2005-07-28 Andrx Pharmaceuticals, Llc Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and an antiulcerative drug
WO2005074930A1 (en) 2004-01-28 2005-08-18 Altana Pharma Ag Pharmaceutical combinations of (s) -pantoprazole with nsaid or corticosteroids
WO2005074536A2 (en) 2004-01-30 2005-08-18 Eisai Co., Ltd. Compositions and methods using proton pump inhibitors
EP1718303A4 (en) * 2004-02-10 2010-09-01 Santarus Inc COMBINATION OF INHIBITOR OF PROTON PUMP, BUFFER AND NON-STEROIDAL ANTI-INFLAMMATORY DRUG
US7460737B2 (en) * 2004-02-12 2008-12-02 Hoshiko Llc Method and apparatus for photograph finding
US20050227949A1 (en) 2004-04-07 2005-10-13 Nasrola Edalatpour Compositions and methods for treatment of viral and bacterial infections
US7813917B2 (en) * 2004-06-22 2010-10-12 Gary Stephen Shuster Candidate matching using algorithmic analysis of candidate-authored narrative information
US20080020041A1 (en) 2004-10-19 2008-01-24 Ayres James W Enteric Coated Compositions that Release Active Ingredient(s) in Gastric Fluid and Intestinal Fluid
US20060165797A1 (en) 2005-01-12 2006-07-27 Pozen Inc. Dosage form for treating gastrointestinal disorders
US20060178349A1 (en) 2005-01-24 2006-08-10 Pozen Inc. Compositions and therapeutic methods utilizing a combination of a 5-HT1F inhibitor and an NSAID
US20060178348A1 (en) 2005-01-24 2006-08-10 Pozen Inc. Compositions and therapeutic methods utilizing a combination of a protein extravasation inhibitor and an NSAID
US8566111B2 (en) * 2005-02-04 2013-10-22 The Invention Science Fund I, Llc Disposition of component virtual property rights
US20080092065A1 (en) * 2005-02-04 2008-04-17 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Third party control over virtual world characters
US20070013691A1 (en) * 2005-07-18 2007-01-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Supervisory authority in virtual world environment
US20060177504A1 (en) 2005-02-08 2006-08-10 Renjit Sundharadas Combination pain medication
EP1726300A1 (en) 2005-05-24 2006-11-29 Flamel Technologies Oral pharmaceutical formulation for the prevention and/or the treatment of cardiovascular and inflammatory diseases
EP1726301A1 (en) 2005-05-24 2006-11-29 Flamel Technologies Oral pharmaceutical composition for treating a COX-2 mediated condition
WO2007030710A2 (en) * 2005-09-08 2007-03-15 Hoshiko, Llc Gaming method
EP1932316A2 (en) * 2005-09-09 2008-06-18 Hoshiko LLC Network router security method
US7779280B2 (en) * 2005-09-16 2010-08-17 Gary Stephen Shuster Low power mode for portable computer system
US7874521B2 (en) * 2005-10-17 2011-01-25 Hoshiko Llc Method and system for aviation navigation
US10148905B2 (en) * 2005-10-19 2018-12-04 Intellectual Ventures I Llc Digital medium with hidden content
US20070093232A1 (en) * 2005-10-21 2007-04-26 Shuster Gary S Management of an alert signal for a telecommunications device
US8577698B2 (en) * 2005-10-25 2013-11-05 Intellectual Ventures I Llc Retail price hedging
US7937320B2 (en) * 2005-11-14 2011-05-03 Hoshiko, Llc Managed purchasing account for defined commodities
AR057181A1 (es) 2005-11-30 2007-11-21 Astra Ab Nueva forma de dosificacion de combinacion
WO2007078874A2 (en) 2005-12-30 2007-07-12 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
EP1993518A4 (en) 2006-03-06 2012-12-12 Pozen Inc DOSAGE FORMS FOR THE ADMINISTRATION OF MEDICINAL COMBINATIONS
US7744464B2 (en) * 2006-09-19 2010-06-29 Gary Stephen Shuster Method of managing a card game, a computer implementation thereof, and a card game kit
US8683386B2 (en) * 2006-10-03 2014-03-25 Brian Mark Shuster Virtual environment for computer game
MX2009004475A (es) 2006-10-27 2009-08-12 Univ Missouri Composiciones que comprenden agentes acido labiles que inhiben la bomba de protones, por lo menos otro agente farmaceuticamente activo y metodos de uso de las misma.
US7803042B2 (en) * 2007-01-17 2010-09-28 Gary Stephen Shuster Card game with common card removal
WO2008101060A1 (en) * 2007-02-14 2008-08-21 Logical Therapeutics, Inc. Method of treating arthritis, pain or inflammation with naproxen 2(methanesulfonyl)ethyl ester and a proton pump inhibitor
CA2685353C (en) * 2007-03-07 2016-04-26 Ideaflood, Inc. Multi-instance, multi-user animation platforms
US20080031950A1 (en) * 2007-04-27 2008-02-07 Nectid Inc. Novel anelgesic combination
US7914144B2 (en) * 2007-05-02 2011-03-29 Gary Stephen Shuster Eyewear with pinhole aperture and lens
US7916619B2 (en) * 2007-05-03 2011-03-29 Gary Stephen Shuster Optically-readable disk with copy protection device
US7804744B2 (en) * 2007-05-03 2010-09-28 Gary Stephen Shuster Optically-readable disk with copy protection device
US8126971B2 (en) * 2007-05-07 2012-02-28 Gary Stephen Shuster E-mail authentication
US20090023771A1 (en) 2007-07-18 2009-01-22 The Curators Of The University Of Missouri Pharmaceutical composition comprising a proton pump inhibitor and protein component
US7769806B2 (en) * 2007-10-24 2010-08-03 Social Communications Company Automated real-time data stream switching in a shared virtual area communication environment
US7809789B2 (en) * 2007-10-25 2010-10-05 Brian Mark Shuster Multi-user animation coupled to bulletin board
US8049756B2 (en) * 2007-10-30 2011-11-01 Brian Mark Shuster Time-dependent client inactivity indicia in a multi-user animation environment
EP2364145A4 (en) 2008-05-30 2013-11-13 Pozen Inc GALENIC FORMS FOR RAPID AND EXTENDED ELEVATION OF GASTRIC PH
US8471843B2 (en) * 2008-07-07 2013-06-25 International Business Machines Corporation Geometric and texture modifications of objects in a virtual universe based on real world user characteristics
US20100005028A1 (en) * 2008-07-07 2010-01-07 International Business Machines Corporation Method and apparatus for interconnecting a plurality of virtual world environments
US9268385B2 (en) * 2008-08-20 2016-02-23 International Business Machines Corporation Introducing selective energy efficiency in a virtual environment
EA201100313A1 (ru) * 2008-09-09 2011-10-31 Астразенека Аб Способ доставки фармацевтической композиции пациенту, нуждающемуся в этом
US8108774B2 (en) * 2008-09-26 2012-01-31 International Business Machines Corporation Avatar appearance transformation in a virtual universe
US20110008432A1 (en) 2009-06-25 2011-01-13 Pozen Inc. Method for Treating a Patient in Need of Aspirin Therapy
US9610502B2 (en) * 2009-07-10 2017-04-04 International Business Machines Corporation Use of real time location information for user authentication and authorization in virtual environments
US8893000B2 (en) * 2009-08-26 2014-11-18 International Business Machines Corporation Relocation between virtual environments based upon promotional and alert conditions
US9785909B2 (en) * 2009-08-27 2017-10-10 International Business Machines Corporation Preventing propagation of malicious content in a virtual universe
US9256896B2 (en) * 2009-08-27 2016-02-09 International Business Machines Corporation Virtual universe rendering based on prioritized metadata terms
US20110047828A1 (en) * 2009-09-02 2011-03-03 Gary Stephen Shuster Remotely controlled footwear disruptor
US20120030289A1 (en) * 2010-07-30 2012-02-02 Avaya Inc. System and method for multi-model, context-sensitive, real-time collaboration
US8717447B2 (en) * 2010-08-20 2014-05-06 Gary Stephen Shuster Remote telepresence gaze direction
US8949964B2 (en) * 2010-08-25 2015-02-03 Gary Stephen Shuster Security key entry using ancillary input device
US20120059886A1 (en) * 2010-08-30 2012-03-08 Gary Stephen Shuster Reply message handling for transient group
US20140372912A9 (en) * 2010-10-30 2014-12-18 Aaron D. Cohen Multi-Dimensional Enhanced World View Experiences, Related Systems and Software, Methods of Use and Production Thereof
JP6101267B2 (ja) * 2011-08-18 2017-03-22 アザーヴァース デジタル インコーポレーテッドＵｔｈｅｒｖｅｒｓｅ Ｄｉｇｉｔａｌ， Ｉｎｃ． 仮想世界の相互作用のシステムおよび方法

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