EA201200016A1 - Лечение приливов, вазомоторных симптомов и ночной потливости с помощью предшественников половых стероидов в комбинации с избирательными (селективными) модуляторами эстрогеновых рецепторов - Google Patents

Лечение приливов, вазомоторных симптомов и ночной потливости с помощью предшественников половых стероидов в комбинации с избирательными (селективными) модуляторами эстрогеновых рецепторов

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Publication number
EA201200016A1
EA201200016A1 EA201200016A EA201200016A EA201200016A1 EA 201200016 A1 EA201200016 A1 EA 201200016A1 EA 201200016 A EA201200016 A EA 201200016A EA 201200016 A EA201200016 A EA 201200016A EA 201200016 A1 EA201200016 A1 EA 201200016A1
Authority
EA
Eurasian Patent Office
Prior art keywords
estrogen receptors
vasomotor symptoms
selective
night
electoral
Prior art date
Application number
EA201200016A
Other languages
English (en)
Russian (ru)
Inventor
Фернанд Лабри
Original Assignee
Эндорешерш, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43306950&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201200016(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Эндорешерш, Инк. filed Critical Эндорешерш, Инк.
Publication of EA201200016A1 publication Critical patent/EA201200016A1/xx

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
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    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Medicinal Chemistry (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EA201200016A 2009-06-16 2010-06-16 Лечение приливов, вазомоторных симптомов и ночной потливости с помощью предшественников половых стероидов в комбинации с избирательными (селективными) модуляторами эстрогеновых рецепторов EA201200016A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18754909P 2009-06-16 2009-06-16
US12/791,174 US20100317635A1 (en) 2009-06-16 2010-06-01 Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators
PCT/CA2010/000898 WO2010145010A1 (fr) 2009-06-16 2010-06-16 Traitement de bouffées de chaleur, de symptômes vasomoteurs et de sueurs nocturnes par des précurseurs de stéroïdes sexuels en combinaison avec des modulateurs sélectifs du récepteur de l'œstrogène

Publications (1)

Publication Number Publication Date
EA201200016A1 true EA201200016A1 (ru) 2012-08-30

Family

ID=43306950

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201200016A EA201200016A1 (ru) 2009-06-16 2010-06-16 Лечение приливов, вазомоторных симптомов и ночной потливости с помощью предшественников половых стероидов в комбинации с избирательными (селективными) модуляторами эстрогеновых рецепторов

Country Status (20)

Country Link
US (4) US20100317635A1 (fr)
EP (3) EP3178480A1 (fr)
JP (4) JP2012530074A (fr)
KR (10) KR20190090088A (fr)
CN (3) CN104352504A (fr)
AR (1) AR077119A1 (fr)
AU (1) AU2010262722A1 (fr)
BR (1) BRPI1011561A2 (fr)
CA (2) CA2893236A1 (fr)
CL (1) CL2011003172A1 (fr)
EA (1) EA201200016A1 (fr)
HK (1) HK1204550A1 (fr)
IL (2) IL216963A (fr)
MA (1) MA33434B1 (fr)
MX (1) MX338290B (fr)
NZ (1) NZ597583A (fr)
SG (3) SG10201912379PA (fr)
TW (1) TWI612044B (fr)
WO (1) WO2010145010A1 (fr)
ZA (1) ZA201109198B (fr)

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US8268806B2 (en) 2007-08-10 2012-09-18 Endorecherche, Inc. Pharmaceutical compositions
MX2012014431A (es) 2010-06-10 2013-02-26 Aragon Pharmaceuticals Inc Modulares del receptor de estrogenos y usos de los mismos.
HUE025350T2 (en) 2011-07-19 2016-02-29 Pantarhei Bioscience Bv Tablets containing dehydroepiandrosterone (DHEA)
WO2013090829A1 (fr) 2011-12-14 2013-06-20 Aragon Pharmaceuticals, Inc. Modulateurs des récepteurs des œstrogènes et ses utilisations
MD20140054A2 (ro) 2011-12-16 2014-10-31 Olema Pharmaceuticals, Inc. Compuşi noi de benzopiran, compoziţii şi utilizări ale acestora
JP2015509538A (ja) * 2012-03-07 2015-03-30 リガンド・ファーマシューティカルズ・インコーポレイテッド １つに統合された恒常性システムとしてのステロイドホルモン経路およびコレステロール経路
WO2014008159A1 (fr) * 2012-07-03 2014-01-09 The University Of North Carolina At Chapel Hill Agents de dégradation sélectifs de récepteur des œstrogènes pour le traitement de tumeurs résistantes au tamoxifène
WO2014203129A1 (fr) 2013-06-19 2014-12-24 Olema Pharmaceuticals, Inc. Combinaisons de composés benzopyrane, leurs compositions et utilisations
WO2014203132A1 (fr) 2013-06-19 2014-12-24 Olema Pharmaceuticals, Inc. Composés de benzopyran substitués, leurs compositions et utilisations
CN103739456A (zh) * 2013-12-03 2014-04-23 镇江圣安医药有限公司 2-（对-（（z-4-氯-1,2-二苯基-1-丁烯基）苯氧基）乙醇的新型衍生物及其应用
US9744177B2 (en) * 2014-03-10 2017-08-29 Endorecherche, Inc. Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM
WO2016174011A1 (fr) * 2015-04-28 2016-11-03 Cutech Srl Compositions comprenant des extraits de valériane
EP3368519B1 (fr) 2015-10-27 2022-04-06 Sun Pharma Advanced Research Company Limited Nouveaux antioestrogènes hétérocycliques
ES2821407T3 (es) * 2016-03-25 2021-04-26 Luoxin Biotechnology Shanghai Co Ltd Compuestos de piperidina sustituidos con indol como agentes degradantes de los receptores de estrógenos
CA3022377A1 (fr) * 2016-04-29 2017-11-02 Board Of Regents, The University Of Texas System Mesure ciblee de l'activite transcriptionnelle liee aux recepteurs hormonaux
CN109640958B (zh) * 2016-05-20 2022-11-22 蔚蓝生物技术股份有限公司 包含选择性雌激素受体调节剂(serm)的阴道递送系统及其用途
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