EA201171370A1 - Универсальные способы определения вирусов гриппа - Google Patents

Универсальные способы определения вирусов гриппа

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Publication number
EA201171370A1
EA201171370A1 EA201171370A EA201171370A EA201171370A1 EA 201171370 A1 EA201171370 A1 EA 201171370A1 EA 201171370 A EA201171370 A EA 201171370A EA 201171370 A EA201171370 A EA 201171370A EA 201171370 A1 EA201171370 A1 EA 201171370A1
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EA
Eurasian Patent Office
Prior art keywords
methods
determination
influenza
virus
quantification
Prior art date
Application number
EA201171370A
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English (en)
Inventor
Бернхард Рот
Original Assignee
Новартис Аг
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Publication date
Application filed by Новартис Аг filed Critical Новартис Аг
Publication of EA201171370A1 publication Critical patent/EA201171370A1/ru

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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16161—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16251—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16261—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

Изобретение относится к непатентованным способам определения и количественной оценки вирусов гриппа. В них может использоваться метод обратной транскрипции (ОТ-ПЦР) в реальном времени (q-PCR), который амплифицирует консервативную область штаммов вируса гриппа А или В. Способы позволяют количественно измерить молекулы РНК вируса гриппа или целые вирусные частицы независимо от конкретного штамма вируса (например, гриппа человека, птиц, свиней). Способы особенно пригодны в качестве диагностических методов или для мониторинга методов получения вакцин.
EA201171370A 2009-05-08 2010-05-10 Универсальные способы определения вирусов гриппа EA201171370A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21570409P 2009-05-08 2009-05-08
US21704509P 2009-05-26 2009-05-26
PCT/IB2010/001158 WO2010128396A2 (en) 2009-05-08 2010-05-10 Generic assays for detection of influenza viruses

Publications (1)

Publication Number Publication Date
EA201171370A1 true EA201171370A1 (ru) 2012-05-30

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US (3) US20120201851A1 (ru)
EP (1) EP2427576B1 (ru)
JP (2) JP5740392B2 (ru)
CN (1) CN102803515A (ru)
AU (1) AU2010244131B2 (ru)
BR (1) BRPI1011432A2 (ru)
CA (1) CA2761194C (ru)
EA (1) EA201171370A1 (ru)
ES (1) ES2592381T3 (ru)
NZ (1) NZ596296A (ru)
SI (1) SI2427576T1 (ru)
WO (1) WO2010128396A2 (ru)

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CN103014176B (zh) * 2012-12-17 2018-04-03 北京大北农科技集团股份有限公司动物医学研究中心 用于猪流感病毒实时荧光定量pcr检测的引物集
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CN111118219B (zh) * 2020-02-06 2023-07-25 广州普世利华科技有限公司 一种快速检测甲型流感病毒的rda方法及试剂盒
CN115074461B (zh) * 2021-03-11 2023-08-25 上海市农业科学院 犬流感病毒、犬冠状病毒和犬呼肠孤病毒的三重pcr检测方法

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Also Published As

Publication number Publication date
CN102803515A (zh) 2012-11-28
US20120201851A1 (en) 2012-08-09
WO2010128396A2 (en) 2010-11-11
BRPI1011432A2 (pt) 2019-09-24
JP2012525837A (ja) 2012-10-25
US20160273057A1 (en) 2016-09-22
AU2010244131A1 (en) 2011-12-01
NZ596296A (en) 2013-08-30
JP5740392B2 (ja) 2015-06-24
EP2427576B1 (en) 2016-06-22
AU2010244131B2 (en) 2014-03-13
SI2427576T1 (sl) 2016-10-28
JP2015165806A (ja) 2015-09-24
US20190382854A1 (en) 2019-12-19
EP2427576A2 (en) 2012-03-14
ES2592381T3 (es) 2016-11-29
CA2761194A1 (en) 2010-11-11
CA2761194C (en) 2018-06-12
WO2010128396A3 (en) 2011-05-12

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