EA201170669A1 - Лечение пирфенидоном пациентов с атипичной функцией печени - Google Patents
Лечение пирфенидоном пациентов с атипичной функцией печениInfo
- Publication number
- EA201170669A1 EA201170669A1 EA201170669A EA201170669A EA201170669A1 EA 201170669 A1 EA201170669 A1 EA 201170669A1 EA 201170669 A EA201170669 A EA 201170669A EA 201170669 A EA201170669 A EA 201170669A EA 201170669 A1 EA201170669 A1 EA 201170669A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pirfenidone
- patient
- pyrphenidone
- patients
- treatment
- Prior art date
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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Abstract
Представлены способы введения пирфенидона пациенту, проявляющему аномальные биомаркеры функции печени в ответ на введение пирфенидона. Способы включают введение пациенту пирфенидона в дозах ниже полной целевой дозы в течение периода времени, с последующим введением пациенту пирфенидона в полной целевой дозе. Способы также включают введение пирфенидона в полной целевой дозе без снижения и введение непрерывно снижающихся доз пирфенидона.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11310708P | 2008-11-10 | 2008-11-10 | |
US12/428,393 US7566729B1 (en) | 2008-11-10 | 2009-04-22 | Modifying pirfenidone treatment for patients with atypical liver function |
US48822809A | 2009-06-19 | 2009-06-19 | |
US22894309P | 2009-07-27 | 2009-07-27 | |
US12/553,292 US7635707B1 (en) | 2008-11-10 | 2009-09-03 | Pirfenidone treatment for patients with atypical liver function |
PCT/US2009/063702 WO2010054294A1 (en) | 2008-11-10 | 2009-11-09 | Pirfenidone treatment for patients with atypical liver function |
Publications (2)
Publication Number | Publication Date |
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EA201170669A1 true EA201170669A1 (ru) | 2011-10-31 |
EA022482B1 EA022482B1 (ru) | 2016-01-29 |
Family
ID=41427890
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201170669A EA022482B1 (ru) | 2008-11-10 | 2009-11-09 | Лечение пирфенидоном пациентов с атипичной функцией печени |
Country Status (39)
Country | Link |
---|---|
US (9) | US7635707B1 (ru) |
EP (4) | EP2500019B1 (ru) |
JP (3) | JP2012508253A (ru) |
KR (1) | KR101699501B1 (ru) |
CN (1) | CN102209543A (ru) |
AP (1) | AP2011005740A0 (ru) |
AT (1) | ATE503480T1 (ru) |
AU (3) | AU2009313302B2 (ru) |
BR (1) | BRPI0921022A2 (ru) |
CA (2) | CA2765402A1 (ru) |
CL (1) | CL2011000966A1 (ru) |
CO (1) | CO6382132A2 (ru) |
CU (1) | CU20110100A7 (ru) |
CY (2) | CY1111595T1 (ru) |
DE (1) | DE602009000986D1 (ru) |
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Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3034994A1 (en) | 2008-06-03 | 2009-12-10 | Intermune, Inc. | Substituted aryl-2 pyridone compounds and use thereof for treating inflammatory and fibrotic disorders |
US7635707B1 (en) | 2008-11-10 | 2009-12-22 | Intermune, Inc. | Pirfenidone treatment for patients with atypical liver function |
AU2010206543A1 (en) * | 2009-01-26 | 2011-07-07 | Intermune, Inc. | Methods for treating acute myocardial infarctions and associated disorders |
US7816383B1 (en) | 2009-12-04 | 2010-10-19 | Intermune, Inc. | Methods of administering pirfenidone therapy |
US10105356B2 (en) | 2011-01-31 | 2018-10-23 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
EP2670242B1 (en) | 2011-01-31 | 2022-03-16 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
MX2011007675A (es) | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
JP5259026B1 (ja) * | 2011-10-13 | 2013-08-07 | 三井化学株式会社 | 高分子圧電材料、およびその製造方法 |
WO2013109856A2 (en) * | 2012-01-18 | 2013-07-25 | Genentech, Inc. | Methods of using fgf19 modulators |
MX346763B (es) | 2012-03-28 | 2017-03-31 | Cell Therapy And Tech S A De C V | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
MX356551B (es) | 2012-08-23 | 2018-06-04 | Grupo Medifarma S A De C V Star | Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné. |
CA2819967C (en) | 2012-08-31 | 2016-03-22 | Intermune, Inc. | Use of pirfenidone concomitantly with ciprofloxacin |
AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
US9682071B2 (en) | 2013-03-15 | 2017-06-20 | Intermune, Inc. | Methods of improving microvascular integrity |
NZ722927A (en) | 2014-01-10 | 2022-07-29 | Avalyn Pharma Inc | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
WO2015112701A1 (en) * | 2014-01-24 | 2015-07-30 | Auspex Pharmaceuticals, Inc. | Substituted n-aryl pyridinones |
US9314442B2 (en) * | 2014-03-25 | 2016-04-19 | Leading BioSciences, Inc. | Compositions for the treatment of autodigestion |
WO2015153683A1 (en) | 2014-04-02 | 2015-10-08 | Intermune, Inc. | Anti-fibrotic pyridinones |
CN114588154A (zh) * | 2015-02-05 | 2022-06-07 | 纪念斯隆凯特林癌症中心 | 用于治疗水肿的组合物和方法 |
MA41544A (fr) * | 2015-02-19 | 2017-12-26 | Novartis Ag | Dosages de panobinostat pour le traitement du myélome multiple |
WO2017097947A1 (en) * | 2015-12-11 | 2017-06-15 | F. Hoffmann-La Roche Ag | Vismodegib and pirfenidone combination therapy |
CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
WO2018026442A1 (en) * | 2016-08-01 | 2018-02-08 | The Regents Of The University Of California | Small molecule inhibition for preventing or treating fibrotic diseases |
MX364040B (es) * | 2016-11-11 | 2019-04-11 | Cell Therapy And Tech S A De C V | Uso farmacéutico de una composición que contiene pirfenidona de liberación prolongada (pfd-lp) para la reversión y tratamiento de la esteatohepatitis humana (nafld/nash). |
AU2018317352B2 (en) * | 2017-08-12 | 2020-11-19 | Aiviva Biopharma, Inc. | Multikinase inhibitors and uses in reproductive and digestive tract fibrosis |
MX366086B (es) | 2017-08-15 | 2019-06-27 | Cell Therapy And Tech S A De C V | Composicion topica semisolida conteniendo un agente antimicrobiano y pirfenidona para el tratamiento de daños cronicos de la piel. |
AU2019321429B2 (en) * | 2018-08-15 | 2022-12-08 | Aiviva Biopharma, Inc. | Multi-kinase inhibitors of VEGF and TGF beta and uses thereof |
WO2021057599A1 (zh) * | 2019-09-26 | 2021-04-01 | 深圳先进技术研究院 | 吡非尼酮在制备防治类风湿性关节炎的药物中的应用 |
AU2020397207A1 (en) | 2019-12-04 | 2022-07-21 | Idorsia Pharmaceuticals Ltd | Combination of an azetidine LPA1 receptor antagonist with pirfenidone and/or nintedanib for use in the treatment of fibrotic diseases |
WO2023161668A1 (en) | 2022-02-28 | 2023-08-31 | Nuformix Technologies Limited | Compositions and methods for treatment of idiopathic pulmonary fibrosis |
Family Cites Families (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1000828A (en) | 1907-07-25 | 1911-08-15 | Pierre Lorillard | Conveyer. |
US4052509A (en) | 1972-12-18 | 1977-10-04 | Affiliated Medical Research, Inc. | Method for reducing serum uric acid levels |
US4042699A (en) | 1972-12-18 | 1977-08-16 | Affiliated Medical Research, Inc. | Method for reducing serum glucose levels |
CA1049411A (en) | 1972-12-18 | 1979-02-27 | Affiliated Medical Research | N-substituted pyridone and general method for preparing pyridones |
CA1244894A (en) | 1985-09-27 | 1988-11-15 | William A. Cole | Low voltage class b amplifier with low value decoupling capacitors |
JPH02215719A (ja) | 1989-02-15 | 1990-08-28 | Yamauchi Akitomo | 線維化病変組織の修復並びに線維化病変の阻止剤 |
US5518729A (en) | 1989-11-22 | 1996-05-21 | Margolin; Solomon B. | Compositions and methods for reparation and prevention of fibrotic lesions |
US5310562A (en) | 1989-11-22 | 1994-05-10 | Margolin Solomon B | Composition and method for reparation and prevention of fibrotic lesions |
US5716632A (en) | 1989-11-22 | 1998-02-10 | Margolin; Solomon B. | Compositions and methods for reparation and prevention of fibrotic lesions |
US6294350B1 (en) | 1997-06-05 | 2001-09-25 | Dalhousie University | Methods for treating fibroproliferative diseases |
US6956044B1 (en) * | 2000-02-21 | 2005-10-18 | Margolin Solomon B | Compositions and methods for treatment of epilepsy |
SE0101762D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | New use |
AU2003240754B2 (en) | 2002-04-10 | 2009-02-26 | Merck Serono Sa | Use of osteoprotegerin for the prevention and/or treatment of fibrosis/sclerosis |
US20060110358A1 (en) | 2002-08-28 | 2006-05-25 | Hsu Henry H | Combination therapy for treatment of fibrotic disorders |
JP4542743B2 (ja) | 2002-12-26 | 2010-09-15 | Kdl株式会社 | ピリドン誘導体の溶液状医薬組成物 |
WO2005013917A2 (en) | 2003-02-28 | 2005-02-17 | Intermune, Inc. | Combination therapy for treating alphavirus infection and liver fibrosis |
US7250905B2 (en) | 2003-04-09 | 2007-07-31 | Mano Dorsey Judd | Virtual antenna technology (VAT) and applications |
JP2007515939A (ja) | 2003-05-09 | 2007-06-21 | セントカー・インコーポレーテツド | IL−23p40特異的免疫グロブリン由来タンパク質、組成物、方法および用途 |
WO2004103296A2 (en) | 2003-05-16 | 2004-12-02 | Intermune, Inc. | Methods of treating idiopathic pulmonary fibrosis |
EP2390262A1 (en) | 2003-05-16 | 2011-11-30 | Intermune, Inc. | Synthetic chemokine receptor ligands and methods of use thereof |
US20080025986A1 (en) | 2003-06-06 | 2008-01-31 | Ozes Osman N | Methods of Treating Tnf-Mediated Disorders |
US20070053877A1 (en) | 2003-08-21 | 2007-03-08 | Intermune, Inc. | Methods of treating idiopathic pulmonary fibrosis |
CN1266144C (zh) | 2003-09-01 | 2006-07-26 | 上海凯曼生物科技有限公司 | 黄芩甙和黄芩甙元的用途和剂型 |
US7407973B2 (en) | 2003-10-24 | 2008-08-05 | Intermune, Inc. | Use of pirfenidone in therapeutic regimens |
EP1684703A4 (en) | 2003-11-05 | 2008-10-01 | Centocor Inc | METHODS AND COMPOSITIONS FOR TREATING PATHOLOGIES ASSOCIATED WITH MCP-1 |
JP4614884B2 (ja) | 2003-11-14 | 2011-01-19 | シャンハイ ゲノミックス インク | ピリドンの誘導体とその使用 |
WO2005067963A1 (en) | 2003-12-23 | 2005-07-28 | Intermune, Inc. | Use of polyethylene glycol-modified interferon-alpha in therapeutic dosing regimens |
DE10394357T5 (de) * | 2003-12-30 | 2007-03-08 | Council Of Scientific & Industrial Research | Oro-dentale-Kräuterpflegezusammensetzung und Verfahren zur Herstellung derselben |
EP1720573A4 (en) | 2004-02-27 | 2008-04-02 | Centocor Inc | METHODS AND COMPOSITIONS FOR TREATING PATHOLOGIES ASSOCIATED WITH IL-13 |
US20070053845A1 (en) | 2004-03-02 | 2007-03-08 | Shiladitya Sengupta | Nanocell drug delivery system |
WO2005110478A2 (en) | 2004-04-13 | 2005-11-24 | Intermune, Inc. | Combination therapy for treating fibrotic disorders |
US20060037057A1 (en) | 2004-05-24 | 2006-02-16 | Sharp Laboratories Of America, Inc. | Method and system of enabling trick play modes using HTTP GET |
US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
AR051444A1 (es) | 2004-09-24 | 2007-01-17 | Centocor Inc | Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos |
US20060246070A1 (en) | 2004-09-30 | 2006-11-02 | Heavner George A | Methods and compositions for treating renal cell carcinoma related pathologies |
CA2583089A1 (en) | 2004-10-05 | 2006-04-20 | Bayer Schering Pharma Aktiengesellschaft | Tafi inhibitors and their use to treat pulmonary fibrosis |
US20060122138A1 (en) | 2004-10-27 | 2006-06-08 | Medimmune, Inc. | Modulators of EphA2 and EphrinA1 for the treatment of fibrosis-related disease |
WO2006050058A2 (en) | 2004-10-28 | 2006-05-11 | The General Hospital Corporation | Methods of detection and therapy of inflamed tissues using immune modulation |
WO2006099445A2 (en) | 2005-03-14 | 2006-09-21 | Massachusetts Institute Of Technology | Nanocells for diagnosis and treatment of diseases and disorders |
WO2006105538A2 (en) | 2005-03-31 | 2006-10-05 | Centocor, Inc. | Methods and compositions for treating il-21 related pathologies |
CN1846699A (zh) | 2005-04-13 | 2006-10-18 | 中南大学湘雅医院 | 1-(取代苯基)-5-甲基-2-(1h) 吡啶酮(i)化合物用于制备抗除肾间质纤维化外其他器官纤维化或组织纤维化药物的应用 |
EP1891051A2 (en) | 2005-04-29 | 2008-02-27 | Celgene Corporation | Solid forms of 1-( 5-(ih-i , 2 , 4 -triazol- 5 -yl)(1h-indazol-3-yl))-3-(2-piperidylethoxy)benzene |
ES2524922T3 (es) | 2005-05-10 | 2014-12-15 | Intermune, Inc. | Derivados de piridona para modular el sistema de proteína cinasa activada por estrés |
AU2006247064A1 (en) | 2005-05-18 | 2006-11-23 | Biogen Idec Inc. | Methods for treating fibrotic conditions |
US20090131312A1 (en) | 2005-05-18 | 2009-05-21 | Lawrence Blatt | Non-natural chemokine receptor ligands and methods of use thereof |
EA015752B1 (ru) | 2005-07-25 | 2011-12-30 | Интермьюн, Инк. | Новые макроциклические ингибиторы репликации вируса гепатита с |
WO2007038264A2 (en) | 2005-09-22 | 2007-04-05 | Biogen Idec Ma Inc. | Gapr-1 methods |
NZ591443A (en) | 2005-09-22 | 2013-04-26 | Intermune Inc | Granule formation of pirfenidone and pharmaceutically acceptable excipients |
US20090170804A1 (en) | 2005-10-31 | 2009-07-02 | Roderick Phillips | Pirfenidone/toll-like receptor (tlr) agonist compositions and methods for using them to stimulate production of granulocyte colonizing stimulating factor (g-csf) |
BRPI0618939A2 (pt) | 2005-11-23 | 2011-09-13 | Intermune Inc | método para modulação de sistema de proteìna quinase ativada por estresse |
US20070203202A1 (en) | 2005-12-02 | 2007-08-30 | Robinson Cynthia Y | Methods of reducing adverse events associated with pirfenidone therapy |
SG174050A1 (en) | 2006-04-13 | 2011-09-29 | Actelion Pharmaceuticals Ltd | Endothelin receptor antagonists for early stage idiopathic pulmonary fibrosis |
US20080003635A1 (en) | 2006-06-12 | 2008-01-03 | Intermune, Inc. | High Throughput Collagen Synthesis Assay |
RU2008152171A (ru) | 2006-07-05 | 2010-08-10 | Интермьюн, Инк. (Us) | Новые ингибиторы вирусной репликации гепатита с |
ES2409756T3 (es) | 2006-12-04 | 2013-06-27 | Promedior, Inc. | Combinación de SAP y de enalapril para su uso en tratamiento de trastornos fibróticos o fibroproliferativos |
ES2882956T3 (es) | 2006-12-18 | 2021-12-03 | Intermune Inc | Método para proporcionar una terapia de pirfenidona a un paciente |
MX2009010633A (es) | 2007-03-30 | 2009-11-26 | Centocor Ortho Biotech Inc | Antagonistas de la quimiocina interleucina-13 y su uso para el tratamiento de enfermedades inflamatorias. |
AU2007201663A1 (en) | 2007-04-16 | 2008-10-30 | Nautilus Biotech | Oral dosage formulations of protease resistant polypeptides |
CA2583716A1 (en) | 2007-04-18 | 2008-10-18 | Nautilus Biotech | Oral dosage formulations of protease resistant polypeptides |
US20080260820A1 (en) | 2007-04-19 | 2008-10-23 | Gilles Borrelly | Oral dosage formulations of protease-resistant polypeptides |
US20080287508A1 (en) | 2007-05-18 | 2008-11-20 | Intermune, Inc. | Altering pharmacokinetics of pirfenidone therapy |
CA3034994A1 (en) | 2008-06-03 | 2009-12-10 | Intermune, Inc. | Substituted aryl-2 pyridone compounds and use thereof for treating inflammatory and fibrotic disorders |
US7566729B1 (en) * | 2008-11-10 | 2009-07-28 | Intermune, Inc. | Modifying pirfenidone treatment for patients with atypical liver function |
US7635707B1 (en) | 2008-11-10 | 2009-12-22 | Intermune, Inc. | Pirfenidone treatment for patients with atypical liver function |
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