EA201170116A1 - Фосфат-связывающие материалы и их применение - Google Patents

Фосфат-связывающие материалы и их применение

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Publication number
EA201170116A1
EA201170116A1 EA201170116A EA201170116A EA201170116A1 EA 201170116 A1 EA201170116 A1 EA 201170116A1 EA 201170116 A EA201170116 A EA 201170116A EA 201170116 A EA201170116 A EA 201170116A EA 201170116 A1 EA201170116 A1 EA 201170116A1
Authority
EA
Eurasian Patent Office
Prior art keywords
materials
phosphate
application
binding materials
modified
Prior art date
Application number
EA201170116A
Other languages
English (en)
Other versions
EA021705B1 (ru
Inventor
Джонатан Джозеф Паувэл
Нано Хорхе Родригес Фариа
Original Assignee
Медикал Ресёрч Каунсил
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Медикал Ресёрч Каунсил filed Critical Медикал Ресёрч Каунсил
Publication of EA201170116A1 publication Critical patent/EA201170116A1/ru
Publication of EA021705B1 publication Critical patent/EA021705B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/015—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/27—Removal of unwanted matter, e.g. deodorisation or detoxification by chemical treatment, by adsorption or by absorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)

Abstract

Описаны фосфат-связывающие материалы и композиции, содержащие указанные материалы, представляющие собой твердые лиганд-модифицированные полиоксогидроксидные материалы с ионами металла, основанные на оксогидроксидах трехвалентного железа, модифицированных лигандами карбоновых кислот или ионизированными формами указанных лигандов. Описанные материалы получены и исследованы в примерах, представленных в настоящей заявке для демонстрации того, что указанные материалы способны связывать фосфат в исследованиях in vitro и in vivo.
EA201170116A 2008-08-05 2009-08-05 Фосфатсвязывающие материалы и их применение EA021705B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8624408P 2008-08-05 2008-08-05
GBGB0814326.5A GB0814326D0 (en) 2008-08-05 2008-08-05 Phosphate binding materials and their uses
PCT/GB2009/001931 WO2010015827A2 (en) 2008-08-05 2009-08-05 Phosphate binding materials and their uses

Publications (2)

Publication Number Publication Date
EA201170116A1 true EA201170116A1 (ru) 2011-08-30
EA021705B1 EA021705B1 (ru) 2015-08-31

Family

ID=39767560

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201170116A EA021705B1 (ru) 2008-08-05 2009-08-05 Фосфатсвязывающие материалы и их применение

Country Status (21)

Country Link
US (1) US7943664B2 (ru)
EP (1) EP2320884B1 (ru)
JP (2) JP5805532B2 (ru)
KR (1) KR101653423B1 (ru)
CN (1) CN102143742B (ru)
AU (1) AU2009278906B9 (ru)
BR (1) BRPI0917503B8 (ru)
CA (1) CA2732226C (ru)
EA (1) EA021705B1 (ru)
ES (1) ES2592315T3 (ru)
GB (2) GB0814326D0 (ru)
HU (1) HUE029874T2 (ru)
IL (1) IL210913A (ru)
LT (1) LT2320884T (ru)
MX (1) MX2011001258A (ru)
PL (1) PL2320884T3 (ru)
PT (1) PT2320884T (ru)
SI (1) SI2320884T1 (ru)
SM (1) SMT201600359B (ru)
WO (1) WO2010015827A2 (ru)
ZA (1) ZA201100821B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2125847T3 (pl) * 2007-02-06 2015-12-31 Medical Res Council Materiały poli okso-hydroksy jonów metalu zmodyfikowanych ligandem, ich zastosowania i sposoby ich otrzymywania
TWI468167B (zh) 2007-11-16 2015-01-11 威佛（國際）股份有限公司 藥學組成物
CN102821843A (zh) * 2010-02-19 2012-12-12 通用电气健康护理生物科学股份公司 色谱介质的制备方法
GB201101299D0 (en) 2011-01-25 2011-03-09 Medical Res Council Oxygen sensors and their uses
WO2013027214A2 (en) 2011-08-22 2013-02-28 Bar-Ilan University Nanop article dialysis
US9370202B2 (en) 2013-03-15 2016-06-21 LG Bionano, LLC Encapsulated metal ion nanoclusters
RS60894B1 (sr) * 2013-11-27 2020-11-30 Vifor Int Ag Farmaceutska kompozicija, koja sadrži čestice vezivnog sredstva za fosfat
WO2016038541A1 (en) * 2014-09-10 2016-03-17 Lupin Limited A manufacturing process for an iron containing adsorbent
GB201517893D0 (en) 2015-10-09 2015-11-25 Medical Res Council Methods for producing carboxylate ligand modified ferric iron hydroxide colloids
US11248018B2 (en) 2016-02-23 2022-02-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Process for preparation of nicotinamide riboside (NR) and cosmetic composition comprising (NR and a phosphate-binding agent
US11136251B2 (en) 2017-03-23 2021-10-05 Regents Of The University Of Minnesota Compositions, methods, and devices for capturing phosphate from water
CN114797781B (zh) * 2022-06-07 2022-12-06 广东粤海水务投资有限公司 一种载镧氮掺杂多孔碳磷吸附材料的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT279048B (de) * 1967-07-04 1970-02-25 Pharmazeutische Fabrik Montavit Gmbh Verfahren zur Herstellung neuer, löslicher und stabiler organischer Eisen(III)-Komplexverbindungen und Injektionslösungen davon
DE4239442C2 (de) * 1992-11-24 2001-09-13 Sebo Gmbh Verwendung eines mit polynuklearen Metalloxidhydroxiden modifizierten Adsorptionsmaterials zur selektiven Elimination von anorganischem Phosphat aus proteinhaltigen Flüssigkeiten
DE19547356A1 (de) * 1995-12-19 1997-06-26 Vifor Int Ag Adsorbens für Phosphat aus wäßrigem Medium, dessen Herstellung und Verwendung
TWI335218B (en) * 2003-02-19 2011-01-01 Panion & Bf Biotech Inc Ferric organic compounds, uses thereof and methods of making same
US6903235B2 (en) 2003-10-08 2005-06-07 Panion & Bf Biotech Inc. Pharmaceutical-grade ferric citrate
MY157620A (en) * 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
PT2319804E (pt) * 2006-12-14 2014-11-24 Novartis Ag Adsorvente de fosfato à base de ferro (iii)-carboidrato
GB0702270D0 (en) * 2007-02-06 2007-03-14 Medical Res Council Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation
PL2125847T3 (pl) * 2007-02-06 2015-12-31 Medical Res Council Materiały poli okso-hydroksy jonów metalu zmodyfikowanych ligandem, ich zastosowania i sposoby ich otrzymywania
TWI468167B (zh) 2007-11-16 2015-01-11 威佛（國際）股份有限公司 藥學組成物

Also Published As

Publication number Publication date
EP2320884A2 (en) 2011-05-18
AU2009278906B9 (en) 2015-04-02
IL210913A0 (en) 2011-04-28
GB0913684D0 (en) 2009-09-16
IL210913A (en) 2014-07-31
CA2732226C (en) 2017-09-12
EA021705B1 (ru) 2015-08-31
GB2462374B (en) 2010-12-22
JP2014205689A (ja) 2014-10-30
JP5805532B2 (ja) 2015-11-04
JP2011529954A (ja) 2011-12-15
LT2320884T (lt) 2016-10-10
ZA201100821B (en) 2011-09-28
AU2009278906B2 (en) 2014-11-13
PT2320884T (pt) 2016-09-22
SI2320884T1 (sl) 2016-11-30
GB2462374A (en) 2010-02-10
WO2010015827A2 (en) 2010-02-11
KR101653423B1 (ko) 2016-09-01
ES2592315T3 (es) 2016-11-29
US7943664B2 (en) 2011-05-17
AU2009278906A1 (en) 2010-02-11
MX2011001258A (es) 2011-04-04
EP2320884B1 (en) 2016-07-13
BRPI0917503A2 (pt) 2015-11-17
CN102143742B (zh) 2015-05-13
US20100032374A1 (en) 2010-02-11
WO2010015827A3 (en) 2010-04-01
BRPI0917503B8 (pt) 2021-05-25
KR20110052680A (ko) 2011-05-18
CA2732226A1 (en) 2010-02-11
CN102143742A (zh) 2011-08-03
GB0814326D0 (en) 2008-09-10
BRPI0917503B1 (pt) 2021-01-05
SMT201600359B (it) 2016-11-10
PL2320884T3 (pl) 2017-01-31
HUE029874T2 (en) 2017-04-28

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