EA201101188A1 - [1,2,4]триазоло[1,5-а]пиридины в качестве ингибиторов киназы - Google Patents

[1,2,4]триазоло[1,5-а]пиридины в качестве ингибиторов киназы

Info

Publication number
EA201101188A1
EA201101188A1 EA201101188A EA201101188A EA201101188A1 EA 201101188 A1 EA201101188 A1 EA 201101188A1 EA 201101188 A EA201101188 A EA 201101188A EA 201101188 A EA201101188 A EA 201101188A EA 201101188 A1 EA201101188 A1 EA 201101188A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
kinase
symptoms
mediated disorder
relates
Prior art date
Application number
EA201101188A
Other languages
English (en)
Inventor
Каролине Лериш
Эрик Оклер
Жак Ле Ру
Дейвид Миддлмисс
Original Assignee
Фовеа Фармасьютикалз
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42229029&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201101188(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Фовеа Фармасьютикалз filed Critical Фовеа Фармасьютикалз
Publication of EA201101188A1 publication Critical patent/EA201101188A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Изобретение относится к определенным новым соединениям, способам их получения и способам лечения или уменьшения симптомов нарушения, опосредованного киназой. Более предпочтительно настоящее изобретение относится к замещенным триазолопиридиновым соединениям, пригодным в качестве селективных ингибиторов киназы, способам получения таких соединений и способам лечения или уменьшения симптомов нарушения, опосредованного киназой. В частности, способ относится к лечению или уменьшению симптомов нарушения, опосредованного киназой, включая сердечно-сосудистые заболевания, диабет, нарушения, связанные с диабетом, воспалительные заболевания, иммунологические нарушения, злокачественное новообразование и заболевания глаз, такие как ретинопатии или дегенерация желтого пятна или другие витреоретинальные заболевания, и другие.
EA201101188A 2009-02-13 2010-02-09 [1,2,4]триазоло[1,5-а]пиридины в качестве ингибиторов киназы EA201101188A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09360013 2009-02-13
PCT/EP2010/051556 WO2010092041A1 (en) 2009-02-13 2010-02-09 [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors

Publications (1)

Publication Number Publication Date
EA201101188A1 true EA201101188A1 (ru) 2012-04-30

Family

ID=42229029

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201101188A EA201101188A1 (ru) 2009-02-13 2010-02-09 [1,2,4]триазоло[1,5-а]пиридины в качестве ингибиторов киназы

Country Status (24)

Country Link
US (1) US20120041195A1 (ru)
EP (1) EP2396324A1 (ru)
JP (1) JP2012517971A (ru)
KR (1) KR20110116160A (ru)
CN (1) CN102317288A (ru)
AR (1) AR075411A1 (ru)
BR (1) BRPI1008850A2 (ru)
CA (1) CA2751517A1 (ru)
CL (1) CL2011001947A1 (ru)
CO (1) CO6420343A2 (ru)
CR (1) CR20110386A (ru)
DO (1) DOP2011000248A (ru)
EA (1) EA201101188A1 (ru)
EC (1) ECSP11011250A (ru)
HN (1) HN2011002095A (ru)
IL (1) IL214426A0 (ru)
MX (1) MX2011008549A (ru)
NI (1) NI201100151A (ru)
NZ (1) NZ594508A (ru)
PE (1) PE20120110A1 (ru)
SG (1) SG173610A1 (ru)
TN (1) TN2011000379A1 (ru)
WO (1) WO2010092041A1 (ru)
ZA (1) ZA201105896B (ru)

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EP2343294A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Substituted triazolopyridines
EP2343297A1 (en) 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridines
EP2343295A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridine derivates
UY33452A (es) * 2010-06-16 2012-01-31 Bayer Schering Pharma Ag Triazolopiridinas sustituidas
TW201204723A (en) * 2010-06-22 2012-02-01 Fovea Pharmaceuticals Heterocyclic compounds, their preparation and their therapeutic application
WO2012143329A1 (en) 2011-04-21 2012-10-26 Bayer Intellectual Property Gmbh Triazolopyridines
WO2012160029A1 (en) 2011-05-23 2012-11-29 Bayer Intellectual Property Gmbh Substituted triazolopyridines
UA112096C2 (uk) 2011-12-12 2016-07-25 Байєр Інтеллектуал Проперті Гмбх Заміщені триазолопіридини та їх застосування як інгібіторів ttk
KR20130091464A (ko) 2012-02-08 2013-08-19 한미약품 주식회사 타이로신 카이네이즈 억제 활성을 갖는 트리아졸로피리딘 유도체
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PE20150354A1 (es) 2012-07-10 2015-03-21 Bayer Pharma AG Metodos para preparar triazolopiridinas sustituidas
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PE20160156A1 (es) 2013-06-11 2016-04-20 Bayer Pharma AG Derivados de prodroga de triazolpiridinas sustituidas
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Also Published As

Publication number Publication date
WO2010092041A1 (en) 2010-08-19
CR20110386A (es) 2011-12-02
PE20120110A1 (es) 2012-02-20
TN2011000379A1 (en) 2013-03-27
MX2011008549A (es) 2011-12-06
IL214426A0 (en) 2011-09-27
US20120041195A1 (en) 2012-02-16
SG173610A1 (en) 2011-09-29
CN102317288A (zh) 2012-01-11
NI201100151A (es) 2012-10-03
DOP2011000248A (es) 2011-10-31
NZ594508A (en) 2013-12-20
EP2396324A1 (en) 2011-12-21
ECSP11011250A (es) 2011-10-31
AR075411A1 (es) 2011-03-30
KR20110116160A (ko) 2011-10-25
BRPI1008850A2 (pt) 2016-03-15
CA2751517A1 (en) 2010-08-19
CO6420343A2 (es) 2012-04-16
ZA201105896B (en) 2012-03-28
CL2011001947A1 (es) 2012-03-16
JP2012517971A (ja) 2012-08-09
HN2011002095A (es) 2014-01-06

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