EA201000266A1 - Эмульсионные лекарственные формы производных пиразолона - Google Patents

Эмульсионные лекарственные формы производных пиразолона

Info

Publication number
EA201000266A1
EA201000266A1 EA201000266A EA201000266A EA201000266A1 EA 201000266 A1 EA201000266 A1 EA 201000266A1 EA 201000266 A EA201000266 A EA 201000266A EA 201000266 A EA201000266 A EA 201000266A EA 201000266 A1 EA201000266 A1 EA 201000266A1
Authority
EA
Eurasian Patent Office
Prior art keywords
derivatives
pyrazolona
emulsion
medical forms
proposed
Prior art date
Application number
EA201000266A
Other languages
English (en)
Other versions
EA018458B1 (ru
Inventor
Киихиро Набэта
Original Assignee
ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК.
Техно Гард Ко. Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК., Техно Гард Ко. Лтд. filed Critical ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК.
Publication of EA201000266A1 publication Critical patent/EA201000266A1/ru
Publication of EA018458B1 publication Critical patent/EA018458B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Предложены эмульсионные лекарственные формы производных пиразолона. Эмульсионные лекарственные формы содержат производное пиразолона, например эдаравон, масло, воду и эмульгатор. Предложены также способы изготовления и применения предложенных эмульсионных лекарственных форм.
EA201000266A 2007-11-21 2008-11-07 Эмульсионные лекарственные формы производных пиразолона EA018458B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98970707P 2007-11-21 2007-11-21
PCT/US2008/082842 WO2009067343A1 (en) 2007-11-21 2008-11-07 Pyrazolone derivative emulsion formulations

Publications (2)

Publication Number Publication Date
EA201000266A1 true EA201000266A1 (ru) 2010-10-29
EA018458B1 EA018458B1 (ru) 2013-08-30

Family

ID=40642635

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201000266A EA018458B1 (ru) 2007-11-21 2008-11-07 Эмульсионные лекарственные формы производных пиразолона

Country Status (13)

Country Link
US (1) US8168670B2 (ru)
EP (1) EP2230912A4 (ru)
JP (1) JP5509090B2 (ru)
KR (2) KR20120125403A (ru)
CN (1) CN101801195A (ru)
AR (1) AR069386A1 (ru)
AU (1) AU2008326593B2 (ru)
BR (1) BRPI0815597A2 (ru)
CA (1) CA2695605C (ru)
EA (1) EA018458B1 (ru)
TW (1) TWI376240B (ru)
WO (1) WO2009067343A1 (ru)
ZA (1) ZA201000780B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101966149B (zh) * 2010-09-25 2012-02-15 西安力邦制药有限公司 一种脑梗塞治疗药物脂肪乳剂的制备
US8747534B2 (en) * 2010-12-29 2014-06-10 United States Gypsum Company Antimicrobial size emulsion and gypsum panel made therewith
CN102058531B (zh) * 2011-01-11 2012-09-19 西安力邦制药有限公司 一种脑保护治疗药物脂肪乳剂的制备
CN111840218B (zh) * 2016-03-16 2022-07-12 苏州澳宗生物科技有限公司 依达拉奉剂型
DK3551181T3 (da) * 2017-01-17 2020-11-30 Treeway Tw001 B V Behandling omfattende oral eller gastrisk indgivelse af edaravone
CN109431966B (zh) * 2018-04-27 2020-09-22 首都医科大学附属北京天坛医院 依达拉奉药物组合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185100A (en) * 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
JPS5931689B2 (ja) * 1978-01-23 1984-08-03 富士写真フイルム株式会社 油溶性写真用添加剤の分散方法
US4360518A (en) * 1979-08-06 1982-11-23 Johnson & Johnson Topical anti-inflammatory drug therapy
DE3308881A1 (de) * 1983-03-12 1984-09-13 Bayer Ag, 5090 Leverkusen Verwendung von pyrazolonderivaten als lipoxygenasehemmer, bei der therapie von ischaemien und herzrhythmusstoerungen sowie von rheumatischen, allergischen und asthmatischen erkrankungen, oedemen, lungenembolien, pulmonaler hypertension, sauerstoffintoxikation und ulcerationen, arzneimittel hierfuer und verfahren zu deren herstellung
DE3312581A1 (de) * 1983-04-08 1984-10-11 Bayer Ag, 5090 Leverkusen Verwendung von pyrazolonderivaten bei der bekaempfung des wachstums von tumorzellen und der metastasenbildung, arzneimittel hierfuer und verfahren zu deren herstellung
US6455525B1 (en) * 1999-11-04 2002-09-24 Cephalon, Inc. Heterocyclic substituted pyrazolones
AU2001267864A1 (en) * 2000-06-29 2002-01-08 Mitsubishi-Tokyo Pharmaceuticals, Inc. Remedial agent for optic nerve disease and the like
WO2002092082A1 (en) * 2001-05-11 2002-11-21 Mitsubishi Pharma Corporation Stable high-concentration injection containing pyrazolone derivative
WO2004063167A1 (ja) * 2003-01-10 2004-07-29 Mitsubishi Pharma Corporation 血液脳関門破綻抑制剤
CN1440749A (zh) * 2003-03-24 2003-09-10 南昌弘益科技有限公司 易达拉封注射剂及其制备工艺——治疗急性脑梗塞
DE102004025357B4 (de) * 2004-05-19 2007-03-29 Beiersdorf Ag Emulsionskonzentrat mit wasserlöslichen und öllöslichen Polymeren und kosmetische Zubereitung enthaltend Emulsionskonzentrat sowie ein Verfahren zu dessen Herstellung und dessen Verwendung
JP4746856B2 (ja) * 2004-08-12 2011-08-10 三笠製薬株式会社 ピラゾロン系製剤
US20070116769A1 (en) * 2004-11-01 2007-05-24 Novozymes A/S Continuous encapsulation process
US20060189682A1 (en) * 2005-02-02 2006-08-24 Payne Joseph E Water soluble prodrugs of COX-2 inhibitors
JP2006298774A (ja) * 2005-04-15 2006-11-02 Lead Chemical Co Ltd 経皮吸収型フリーラジカル抑制製剤
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby

Also Published As

Publication number Publication date
CN101801195A (zh) 2010-08-11
US8168670B2 (en) 2012-05-01
EA018458B1 (ru) 2013-08-30
AU2008326593A1 (en) 2009-05-28
JP2011504177A (ja) 2011-02-03
KR20120125403A (ko) 2012-11-14
BRPI0815597A2 (pt) 2014-09-30
AU2008326593B2 (en) 2013-09-05
ZA201000780B (en) 2011-04-28
WO2009067343A1 (en) 2009-05-28
TW200936181A (en) 2009-09-01
KR101235085B1 (ko) 2013-02-20
AR069386A1 (es) 2010-01-20
KR20100091939A (ko) 2010-08-19
TWI376240B (en) 2012-11-11
EP2230912A4 (en) 2013-05-01
CA2695605C (en) 2013-04-09
US20090131496A1 (en) 2009-05-21
EP2230912A1 (en) 2010-09-29
CA2695605A1 (en) 2009-05-28
JP5509090B2 (ja) 2014-06-04

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU