EA200970710A1 - ПРОИЗВОДНЫЕ 2-ПИПЕРАЗИН-1-ИЛ-3Н-ИМИДАЗО[4,5-b]ПИРИДИНА - Google Patents

ПРОИЗВОДНЫЕ 2-ПИПЕРАЗИН-1-ИЛ-3Н-ИМИДАЗО[4,5-b]ПИРИДИНА

Info

Publication number
EA200970710A1
EA200970710A1 EA200970710A EA200970710A EA200970710A1 EA 200970710 A1 EA200970710 A1 EA 200970710A1 EA 200970710 A EA200970710 A EA 200970710A EA 200970710 A EA200970710 A EA 200970710A EA 200970710 A1 EA200970710 A1 EA 200970710A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compounds
piperazin
imidazo
pyridine
derivatives
Prior art date
Application number
EA200970710A
Other languages
English (en)
Other versions
EA016422B1 (ru
Inventor
Франс Эдуард Янссенс
Жером Эмиль Жорж Гийемон
Франсуа Мария Соммен
Жан-Франсуа Бонфанти
Original Assignee
Янссен Фармацевтика Нв
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика Нв filed Critical Янссен Фармацевтика Нв
Publication of EA200970710A1 publication Critical patent/EA200970710A1/ru
Publication of EA016422B1 publication Critical patent/EA016422B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Настоящее изобретение связано с новыми соединениями формулы (I), обладающими релаксационной активностью в отношении фундальной части желудка. Изобретение дополнительно относится к способам получения таких соединений, к фармацевтическим композициям, содержащим упомянутые соединения, а также к применению упомянутых соединений в качестве лекарственного препарата.
EA200970710A 2007-01-25 2008-01-24 ПРОИЗВОДНЫЕ 2-ПИПЕРАЗИН-1-ИЛ-3Н-ИМИДАЗО[4,5-b]ПИРИДИНА EA016422B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07101153 2007-01-25
PCT/EP2008/050818 WO2008090200A2 (en) 2007-01-25 2008-01-24 2- piperazin-1-yl-3h-imidazo[4,5-b]pyridine derivatives

Publications (2)

Publication Number Publication Date
EA200970710A1 true EA200970710A1 (ru) 2009-12-30
EA016422B1 EA016422B1 (ru) 2012-04-30

Family

ID=38179852

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200970710A EA016422B1 (ru) 2007-01-25 2008-01-24 ПРОИЗВОДНЫЕ 2-ПИПЕРАЗИН-1-ИЛ-3Н-ИМИДАЗО[4,5-b]ПИРИДИНА

Country Status (18)

Country Link
US (1) US7994173B2 (ru)
EP (1) EP2121683B1 (ru)
JP (1) JP5437814B2 (ru)
KR (1) KR101484027B1 (ru)
CN (1) CN101600717B (ru)
AT (1) ATE522530T1 (ru)
AU (1) AU2008208820B2 (ru)
BR (1) BRPI0807799B8 (ru)
CA (1) CA2671857C (ru)
EA (1) EA016422B1 (ru)
ES (1) ES2372433T3 (ru)
HK (1) HK1136288A1 (ru)
IL (1) IL199986A (ru)
MX (1) MX2009007912A (ru)
PL (1) PL2121683T3 (ru)
UA (1) UA101149C2 (ru)
WO (1) WO2008090200A2 (ru)
ZA (1) ZA200905205B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
ES2038532B1 (es) * 1991-05-10 1994-02-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de 2-piperacinilbecimidazol.
DE60025261T2 (de) * 1999-11-23 2006-08-24 Janssen Pharmaceutica N.V. Verwendung von 5ht3 antagonisten zur fundusentspannung
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues

Also Published As

Publication number Publication date
KR20090101464A (ko) 2009-09-28
US7994173B2 (en) 2011-08-09
CA2671857A1 (en) 2008-07-31
ZA200905205B (en) 2010-09-29
JP2010516740A (ja) 2010-05-20
HK1136288A1 (ru) 2010-06-25
CA2671857C (en) 2013-11-19
IL199986A (en) 2013-03-24
PL2121683T3 (pl) 2012-01-31
BRPI0807799B1 (pt) 2021-04-06
AU2008208820B2 (en) 2012-09-20
WO2008090200A2 (en) 2008-07-31
EA016422B1 (ru) 2012-04-30
BRPI0807799B8 (pt) 2021-05-25
ATE522530T1 (de) 2011-09-15
EP2121683A2 (en) 2009-11-25
WO2008090200A3 (en) 2008-09-04
ES2372433T3 (es) 2012-01-19
KR101484027B1 (ko) 2015-01-19
EP2121683B1 (en) 2011-08-31
CN101600717B (zh) 2013-03-13
US20100004260A1 (en) 2010-01-07
BRPI0807799A2 (pt) 2014-06-03
MX2009007912A (es) 2009-07-31
UA101149C2 (en) 2013-03-11
IL199986A0 (en) 2010-04-15
AU2008208820A1 (en) 2008-07-31
CN101600717A (zh) 2009-12-09
JP5437814B2 (ja) 2014-03-12

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM