MX2009007912A - Derivados de 2-piperazin-1-il-3h-imidazo[4,5-b]piridina. - Google Patents

Derivados de 2-piperazin-1-il-3h-imidazo[4,5-b]piridina.

Info

Publication number
MX2009007912A
MX2009007912A MX2009007912A MX2009007912A MX2009007912A MX 2009007912 A MX2009007912 A MX 2009007912A MX 2009007912 A MX2009007912 A MX 2009007912A MX 2009007912 A MX2009007912 A MX 2009007912A MX 2009007912 A MX2009007912 A MX 2009007912A
Authority
MX
Mexico
Prior art keywords
piperazin
imidazo
compounds
pyridine derivatives
concerned
Prior art date
Application number
MX2009007912A
Other languages
English (en)
Inventor
Jerome Emile Georges Guillemont
Jean-Francois Bonfanti
Frans Eduard Janssens
Francois Maria Sommen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX2009007912A publication Critical patent/MX2009007912A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a compuestos novedosos de fórmula (I) (ver fórmula I) que tienen actividad de relajación fúndica; la invención además se relaciona con métodos para la preparación de dichos compuestos, composiciones farmacéuticas que comprenden dichos compuestos así como el uso como una medicina de dichos compuestos.
MX2009007912A 2007-01-25 2008-01-24 Derivados de 2-piperazin-1-il-3h-imidazo[4,5-b]piridina. MX2009007912A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07101153 2007-01-25
PCT/EP2008/050818 WO2008090200A2 (en) 2007-01-25 2008-01-24 2- piperazin-1-yl-3h-imidazo[4,5-b]pyridine derivatives

Publications (1)

Publication Number Publication Date
MX2009007912A true MX2009007912A (es) 2009-07-31

Family

ID=38179852

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009007912A MX2009007912A (es) 2007-01-25 2008-01-24 Derivados de 2-piperazin-1-il-3h-imidazo[4,5-b]piridina.

Country Status (18)

Country Link
US (1) US7994173B2 (es)
EP (1) EP2121683B1 (es)
JP (1) JP5437814B2 (es)
KR (1) KR101484027B1 (es)
CN (1) CN101600717B (es)
AT (1) ATE522530T1 (es)
AU (1) AU2008208820B2 (es)
BR (1) BRPI0807799B8 (es)
CA (1) CA2671857C (es)
EA (1) EA016422B1 (es)
ES (1) ES2372433T3 (es)
HK (1) HK1136288A1 (es)
IL (1) IL199986A (es)
MX (1) MX2009007912A (es)
PL (1) PL2121683T3 (es)
UA (1) UA101149C2 (es)
WO (1) WO2008090200A2 (es)
ZA (1) ZA200905205B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
ES2038532B1 (es) * 1991-05-10 1994-02-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de 2-piperacinilbecimidazol.
WO2001037824A1 (en) * 1999-11-23 2001-05-31 Janssen Pharmaceutica N.V. Use of 5ht3 agonists for relaxing the fundus
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues

Also Published As

Publication number Publication date
JP2010516740A (ja) 2010-05-20
ATE522530T1 (de) 2011-09-15
AU2008208820A1 (en) 2008-07-31
BRPI0807799B1 (pt) 2021-04-06
HK1136288A1 (es) 2010-06-25
CN101600717A (zh) 2009-12-09
WO2008090200A3 (en) 2008-09-04
AU2008208820B2 (en) 2012-09-20
IL199986A0 (en) 2010-04-15
KR20090101464A (ko) 2009-09-28
IL199986A (en) 2013-03-24
BRPI0807799A2 (pt) 2014-06-03
JP5437814B2 (ja) 2014-03-12
ZA200905205B (en) 2010-09-29
EP2121683B1 (en) 2011-08-31
EA200970710A1 (ru) 2009-12-30
BRPI0807799B8 (pt) 2021-05-25
EP2121683A2 (en) 2009-11-25
WO2008090200A2 (en) 2008-07-31
CA2671857C (en) 2013-11-19
CA2671857A1 (en) 2008-07-31
ES2372433T3 (es) 2012-01-19
PL2121683T3 (pl) 2012-01-31
US20100004260A1 (en) 2010-01-07
US7994173B2 (en) 2011-08-09
EA016422B1 (ru) 2012-04-30
KR101484027B1 (ko) 2015-01-19
UA101149C2 (en) 2013-03-11
CN101600717B (zh) 2013-03-13

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Legal Events

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FG Grant or registration