UA101149C2 - 2-piperazin-1-yl-3h-imidazo[4,5-b]pyridine derivatives - Google Patents

2-piperazin-1-yl-3h-imidazo[4,5-b]pyridine derivatives

Info

Publication number
UA101149C2
UA101149C2 UAA200906700A UAA200906700A UA101149C2 UA 101149 C2 UA101149 C2 UA 101149C2 UA A200906700 A UAA200906700 A UA A200906700A UA A200906700 A UAA200906700 A UA A200906700A UA 101149 C2 UA101149 C2 UA 101149C2
Authority
UA
Ukraine
Prior art keywords
piperazin
imidazo
compounds
pyridine derivatives
concerned
Prior art date
Application number
UAA200906700A
Other languages
English (en)
Ukrainian (uk)
Inventor
Франс Эдуард Янссенс
Жером Эмиль Жорж Жильмон
Франсуа Мария Соммен
Жан-Франсуа Бонфанти
Original Assignee
Янссен Фармацевтика Нв
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика Нв filed Critical Янссен Фармацевтика Нв
Publication of UA101149C2 publication Critical patent/UA101149C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Данное изобретение связано с новыми соединениями формулы (I), которые имеют релаксационную активность относительно фундальной части желудка.Изобретение дополнительно касается способов получения таких соединений, фармацевтических композиций, которые содержат упомянутые соединения, а также применения упомянутых соединений в качестве лекарственного препарата.(I)
UAA200906700A 2007-01-25 2008-01-24 2-piperazin-1-yl-3h-imidazo[4,5-b]pyridine derivatives UA101149C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07101153 2007-01-25
PCT/EP2008/050818 WO2008090200A2 (en) 2007-01-25 2008-01-24 2- piperazin-1-yl-3h-imidazo[4,5-b]pyridine derivatives

Publications (1)

Publication Number Publication Date
UA101149C2 true UA101149C2 (en) 2013-03-11

Family

ID=38179852

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200906700A UA101149C2 (en) 2007-01-25 2008-01-24 2-piperazin-1-yl-3h-imidazo[4,5-b]pyridine derivatives

Country Status (18)

Country Link
US (1) US7994173B2 (ru)
EP (1) EP2121683B1 (ru)
JP (1) JP5437814B2 (ru)
KR (1) KR101484027B1 (ru)
CN (1) CN101600717B (ru)
AT (1) ATE522530T1 (ru)
AU (1) AU2008208820B2 (ru)
BR (1) BRPI0807799B8 (ru)
CA (1) CA2671857C (ru)
EA (1) EA016422B1 (ru)
ES (1) ES2372433T3 (ru)
HK (1) HK1136288A1 (ru)
IL (1) IL199986A (ru)
MX (1) MX2009007912A (ru)
PL (1) PL2121683T3 (ru)
UA (1) UA101149C2 (ru)
WO (1) WO2008090200A2 (ru)
ZA (1) ZA200905205B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
ES2038532B1 (es) * 1991-05-10 1994-02-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de 2-piperacinilbecimidazol.
WO2001037824A1 (en) * 1999-11-23 2001-05-31 Janssen Pharmaceutica N.V. Use of 5ht3 agonists for relaxing the fundus
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues

Also Published As

Publication number Publication date
AU2008208820A1 (en) 2008-07-31
AU2008208820B2 (en) 2012-09-20
ATE522530T1 (de) 2011-09-15
EP2121683B1 (en) 2011-08-31
CA2671857A1 (en) 2008-07-31
ES2372433T3 (es) 2012-01-19
JP2010516740A (ja) 2010-05-20
IL199986A0 (en) 2010-04-15
CN101600717A (zh) 2009-12-09
US20100004260A1 (en) 2010-01-07
EA016422B1 (ru) 2012-04-30
BRPI0807799A2 (pt) 2014-06-03
MX2009007912A (es) 2009-07-31
EP2121683A2 (en) 2009-11-25
WO2008090200A3 (en) 2008-09-04
KR20090101464A (ko) 2009-09-28
BRPI0807799B8 (pt) 2021-05-25
WO2008090200A2 (en) 2008-07-31
US7994173B2 (en) 2011-08-09
EA200970710A1 (ru) 2009-12-30
JP5437814B2 (ja) 2014-03-12
ZA200905205B (en) 2010-09-29
HK1136288A1 (ru) 2010-06-25
CN101600717B (zh) 2013-03-13
IL199986A (en) 2013-03-24
KR101484027B1 (ko) 2015-01-19
BRPI0807799B1 (pt) 2021-04-06
CA2671857C (en) 2013-11-19
PL2121683T3 (pl) 2012-01-31

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