EA200901031A1 - Модуляторы склеростин-связывающих партнеров для лечения костных расстройств - Google Patents
Модуляторы склеростин-связывающих партнеров для лечения костных расстройствInfo
- Publication number
- EA200901031A1 EA200901031A1 EA200901031A EA200901031A EA200901031A1 EA 200901031 A1 EA200901031 A1 EA 200901031A1 EA 200901031 A EA200901031 A EA 200901031A EA 200901031 A EA200901031 A EA 200901031A EA 200901031 A1 EA200901031 A1 EA 200901031A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- sclerostin
- bone
- treatment
- modulators
- disorders
- Prior art date
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/12—Antihypertensives
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Abstract
В заявке описано применение модуляторов взаимодействия склеростин:склеростин-связывающий партнер для лечения, облегчения и диагностики расстройств, связанных со склеростином, например остеопороза и склеростеоза, и расстройств, связанных со склеростином, например рака и сердечно-сосудистых расстройств. В заявке также описано применение миметиков склеростин-связывающего партнера для лечения, облегчения и диагностики склеростин-связанных расстройств. Также предусмотрены исследования по идентификации модуляторов взаимодействия склеростин:склеростин-связывающий партнер, а также возникающей передачи сигнала.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88795607P | 2007-02-02 | 2007-02-02 | |
PCT/EP2008/051128 WO2008092894A1 (en) | 2007-02-02 | 2008-01-30 | Modulators of sclerostin binding partners for treating bone-related disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200901031A1 true EA200901031A1 (ru) | 2010-04-30 |
Family
ID=39298321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200901031A EA200901031A1 (ru) | 2007-02-02 | 2008-01-30 | Модуляторы склеростин-связывающих партнеров для лечения костных расстройств |
Country Status (16)
Country | Link |
---|---|
US (3) | US20100028335A1 (ru) |
EP (1) | EP2114435A1 (ru) |
JP (1) | JP2010526766A (ru) |
KR (1) | KR20090115133A (ru) |
CN (1) | CN101616684A (ru) |
AU (1) | AU2008209713B2 (ru) |
BR (1) | BRPI0807205A2 (ru) |
CA (1) | CA2675639A1 (ru) |
EA (1) | EA200901031A1 (ru) |
IL (1) | IL199834A0 (ru) |
MA (1) | MA31156B1 (ru) |
MX (1) | MX2009008096A (ru) |
NZ (1) | NZ578235A (ru) |
TN (1) | TN2009000323A1 (ru) |
WO (1) | WO2008092894A1 (ru) |
ZA (1) | ZA200904676B (ru) |
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EP1981910B1 (en) * | 2006-01-13 | 2013-06-26 | A Chan Holding B.V. | Method for identifying inhibitor of the glypican-sclerostin interaction |
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CN110499285A (zh) * | 2018-05-17 | 2019-11-26 | 西安组织工程与再生医学研究所 | Alpl基因在制备预防和/或治疗低碱性磷酸酶症的产品中的应用 |
CN112584823A (zh) * | 2018-06-22 | 2021-03-30 | 纽约哥伦比亚大学理事会 | 用于治疗颞颌关节退化的缓释组成物及方法 |
KR20210043607A (ko) | 2018-08-10 | 2021-04-21 | 암젠 인크 | 항체 제약 제형의 제조 방법 |
CN109734795B (zh) * | 2019-01-17 | 2022-07-12 | 武汉明德生物科技股份有限公司 | 人Lrp4抗原、人Lrp4抗体检测试剂盒及其制备方法与应用 |
WO2020163876A1 (en) * | 2019-02-08 | 2020-08-13 | The Regents Of The University Of California | Compositions and methods involving layilin |
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CN112656806B (zh) * | 2020-12-24 | 2022-08-26 | 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) | 多配体蛋白聚糖4的siRNA序列在抑制犬瘟热病毒复制中的应用 |
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AU2002258592A1 (en) * | 2001-03-23 | 2002-11-25 | The Burnham Institute | Compositions and methods for modulating bone mineral deposition |
JP4662714B2 (ja) * | 2002-03-01 | 2011-03-30 | セルテック アール アンド ディー インコーポレイテッド | 骨密度を増減させる方法 |
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BRPI0414446A (pt) * | 2003-09-18 | 2006-11-14 | Genmab As | métodos para triar um agente terapêutico, para a supressão da sequência de polinucleotìdeo, para o tratamento de um cáncer não dependente de esteróide, para triar a ligação de um agente especificamente a um polinucleotìdeo e para determinar se um paciente está em risco de desenvolver ou ter um cáncer não dependente de esteróide, composição farmacêutica, usos de um agente terapêutico, de uma molécula anti-sentido ou de uma célula que expressa e/ou contém a molécula anti-sentido, de pelo menos uma das proteìnas de membrana imunogênicas, fragmentos, derivados ou homólogos destas ou de uma célula que contém e/ou que expressa pelo menos uma das proteìnas de membranas imunogênicas ou fragmentos, derivados ou homólogos destas e de um agente ou anticorpo, agente, e, kit para identificar um paciente em risco de desenvolver ou ter cáncer não dependente de esteróide |
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WO2007021003A1 (ja) * | 2005-08-18 | 2007-02-22 | Eisai R & D Management Co., Ltd. | ドーパミン産生ニューロン増殖前駆細胞マーカーNato3 |
EP1981910B1 (en) * | 2006-01-13 | 2013-06-26 | A Chan Holding B.V. | Method for identifying inhibitor of the glypican-sclerostin interaction |
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2008
- 2008-01-30 EA EA200901031A patent/EA200901031A1/ru unknown
- 2008-01-30 KR KR1020097016132A patent/KR20090115133A/ko not_active Application Discontinuation
- 2008-01-30 NZ NZ578235A patent/NZ578235A/en not_active IP Right Cessation
- 2008-01-30 US US12/525,631 patent/US20100028335A1/en not_active Abandoned
- 2008-01-30 EP EP08708443A patent/EP2114435A1/en not_active Withdrawn
- 2008-01-30 BR BRPI0807205-1A patent/BRPI0807205A2/pt not_active IP Right Cessation
- 2008-01-30 JP JP2009547684A patent/JP2010526766A/ja active Pending
- 2008-01-30 AU AU2008209713A patent/AU2008209713B2/en not_active Ceased
- 2008-01-30 CA CA002675639A patent/CA2675639A1/en not_active Abandoned
- 2008-01-30 MX MX2009008096A patent/MX2009008096A/es not_active Application Discontinuation
- 2008-01-30 WO PCT/EP2008/051128 patent/WO2008092894A1/en active Application Filing
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- 2009-07-31 TN TNP2009000323A patent/TN2009000323A1/fr unknown
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2013
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IL199834A0 (en) | 2010-04-15 |
TN2009000323A1 (en) | 2010-12-31 |
CN101616684A (zh) | 2009-12-30 |
AU2008209713B2 (en) | 2012-01-19 |
AU2008209713A1 (en) | 2008-08-07 |
NZ578235A (en) | 2012-05-25 |
BRPI0807205A2 (pt) | 2014-07-22 |
WO2008092894A1 (en) | 2008-08-07 |
ZA200904676B (en) | 2010-04-28 |
EP2114435A1 (en) | 2009-11-11 |
US20120003219A1 (en) | 2012-01-05 |
CA2675639A1 (en) | 2008-08-07 |
KR20090115133A (ko) | 2009-11-04 |
JP2010526766A (ja) | 2010-08-05 |
US20100028335A1 (en) | 2010-02-04 |
MA31156B1 (fr) | 2010-02-01 |
MX2009008096A (es) | 2009-08-07 |
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