EA200701805A1 - Состав аэрозоля для дозирующих ингаляторов под давлением - Google Patents

Состав аэрозоля для дозирующих ингаляторов под давлением

Info

Publication number
EA200701805A1
EA200701805A1 EA200701805A EA200701805A EA200701805A1 EA 200701805 A1 EA200701805 A1 EA 200701805A1 EA 200701805 A EA200701805 A EA 200701805A EA 200701805 A EA200701805 A EA 200701805A EA 200701805 A1 EA200701805 A1 EA 200701805A1
Authority
EA
Eurasian Patent Office
Prior art keywords
aerosol
composition
under pressure
dosing inhalers
inhalers under
Prior art date
Application number
EA200701805A
Other languages
English (en)
Other versions
EA013405B1 (ru
Inventor
Дэвид Эндрю Льюис
Брайан Джон Миакин
Маурицио Дельканале
Фаусто Пиветти
Original Assignee
Кьези Фармачеутичи С. П. А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36490097&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200701805(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Кьези Фармачеутичи С. П. А. filed Critical Кьези Фармачеутичи С. П. А.
Publication of EA200701805A1 publication Critical patent/EA200701805A1/ru
Publication of EA013405B1 publication Critical patent/EA013405B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Предложен состав раствора для получения аэрозоля для применения в аэрозольном ингаляторе, который содержит по меньшей мере один активный ингредиент, выбранный из группы, состоящей из 20 кетостероидов и производных хинолинона, пропеллент, содержащий фторалкан, и сорастворитель и стабилизирован путем добавления определенного количества секвестранта.
EA200701805A 2005-02-25 2006-02-13 Состав аэрозоля для дозирующих ингаляторов под давлением EA013405B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05004233 2005-02-25
PCT/EP2006/001287 WO2006089656A2 (en) 2005-02-25 2006-02-13 Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent

Publications (2)

Publication Number Publication Date
EA200701805A1 true EA200701805A1 (ru) 2008-02-28
EA013405B1 EA013405B1 (ru) 2010-04-30

Family

ID=36490097

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200701805A EA013405B1 (ru) 2005-02-25 2006-02-13 Состав аэрозоля для дозирующих ингаляторов под давлением

Country Status (23)

Country Link
US (1) US8877164B2 (ru)
EP (1) EP1850831B1 (ru)
JP (1) JP5259193B2 (ru)
KR (1) KR101313959B1 (ru)
CN (1) CN101119706B (ru)
AR (2) AR054230A1 (ru)
AU (1) AU2006218177B2 (ru)
BR (1) BRPI0607990A2 (ru)
CA (1) CA2594127C (ru)
EA (1) EA013405B1 (ru)
GE (1) GEP20105040B (ru)
HK (1) HK1116337A1 (ru)
IL (1) IL184449A0 (ru)
MA (1) MA29333B1 (ru)
MX (1) MX2007010396A (ru)
NO (1) NO20074854L (ru)
NZ (1) NZ556376A (ru)
PE (1) PE20061011A1 (ru)
SG (1) SG159550A1 (ru)
TN (1) TNSN07289A1 (ru)
UA (1) UA92732C2 (ru)
WO (1) WO2006089656A2 (ru)
ZA (1) ZA200706870B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014133410A1 (ru) * 2013-02-27 2014-09-04 Шолекс Девелопмент Гмбх Аэрозольный препарат на основе ипратропия бромида для лечения заболеваний органов дыхания

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005112902A2 (en) * 2004-05-13 2005-12-01 Chiesi Farmaceutici S.P.A. Medicinal aerosol formulation products with improved chemical stability
GB201200525D0 (en) * 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
US10034866B2 (en) * 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
US11826382B2 (en) 2020-05-01 2023-11-28 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
US11642372B2 (en) 2020-05-01 2023-05-09 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA939195B (en) * 1992-12-09 1995-06-08 Boehringer Ingelheim Pharma Stabilized medicinal aerosol solution formulations
SK280911B6 (sk) * 1992-12-09 2000-09-12 Boehringer Ingelheim Pharmaceuticals, Inc. Farmaceutický prostriedok
DE69424181T2 (de) 1993-12-20 2000-10-19 Minnesota Mining & Mfg Flunisolide aerosolformulierungen
CA2223385A1 (en) * 1995-06-07 1996-12-19 Rhone-Poulenc Rorer Pharmaceuticals Inc. Stabilized steroid compositions
IL122752A (en) * 1995-06-27 2001-07-24 Boehringer Ingelheim Kg Stable preparations for creating propellant-free sprays
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) * 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
AU2001257621A1 (en) * 2000-05-17 2001-11-26 Chrysalis Technologies, Incorporated Stabilized budesonide solution and method for making same
ME00220B (me) * 2000-05-22 2010-10-10 Chiesi Farm Spa Stabilne farmaceutske formulacije rastvora za inhalatore odmjerene doze pod pritiskom
ATE465712T1 (de) * 2002-03-01 2010-05-15 Chiesi Farma Spa Ultrafeine zusammensetzungen von formoterol
DK1497289T3 (da) 2002-04-12 2005-10-24 Boehringer Ingelheim Pharma Lægemiddel indeholdende betamimetika og et nyt anticholinergikum
US7417051B2 (en) * 2002-04-12 2008-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments comprising betamimetics and a novel anticholinergic
DE10230769A1 (de) 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und PDE-IV-Inhibitoren
US20040058950A1 (en) * 2002-07-09 2004-03-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors
DE10237739A1 (de) 2002-08-17 2004-02-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative Arzneimittel enthaltend ein neues Anticholinergikum in Kombination mit Corticosteroiden und Betamimetika
US20040235811A1 (en) * 2002-10-08 2004-11-25 Sepracor Inc. Fatty acid modified forms of glucocorticoids
EP1595531A1 (en) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014133410A1 (ru) * 2013-02-27 2014-09-04 Шолекс Девелопмент Гмбх Аэрозольный препарат на основе ипратропия бромида для лечения заболеваний органов дыхания

Also Published As

Publication number Publication date
TNSN07289A1 (en) 2008-12-31
SG159550A1 (en) 2010-03-30
CA2594127A1 (en) 2006-08-31
GEP20105040B (en) 2010-07-12
CA2594127C (en) 2013-10-15
AR054230A1 (es) 2007-06-13
WO2006089656A2 (en) 2006-08-31
CN101119706A (zh) 2008-02-06
PE20061011A1 (es) 2006-12-08
EA013405B1 (ru) 2010-04-30
JP5259193B2 (ja) 2013-08-07
JP2008537729A (ja) 2008-09-25
NO20074854L (no) 2007-09-24
MX2007010396A (es) 2007-10-19
EP1850831A2 (en) 2007-11-07
IL184449A0 (en) 2007-10-31
WO2006089656A3 (en) 2006-12-21
ZA200706870B (en) 2008-11-26
MA29333B1 (fr) 2008-03-03
NZ556376A (en) 2010-01-29
CN101119706B (zh) 2013-04-17
AR099963A2 (es) 2016-08-31
US20060193785A1 (en) 2006-08-31
EP1850831B1 (en) 2015-12-02
KR20070107002A (ko) 2007-11-06
HK1116337A1 (en) 2008-12-19
BRPI0607990A2 (pt) 2009-10-27
KR101313959B1 (ko) 2013-10-02
AU2006218177A1 (en) 2006-08-31
AU2006218177B2 (en) 2012-04-12
US8877164B2 (en) 2014-11-04
UA92732C2 (ru) 2010-12-10

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU