UA92732C2 - Фармацевтические аэрозольные композиции для ингаляторов под давлением с вымеренными дозами, которые содержат связующее соединение - Google Patents

Фармацевтические аэрозольные композиции для ингаляторов под давлением с вымеренными дозами, которые содержат связующее соединение

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Publication number
UA92732C2
UA92732C2 UAA200707949A UAA200707949A UA92732C2 UA 92732 C2 UA92732 C2 UA 92732C2 UA A200707949 A UAA200707949 A UA A200707949A UA A200707949 A UAA200707949 A UA A200707949A UA 92732 C2 UA92732 C2 UA 92732C2
Authority
UA
Ukraine
Prior art keywords
sequestering agent
metered dose
aerosol formulations
dose inhalers
pressurized metered
Prior art date
Application number
UAA200707949A
Other languages
English (en)
Ukrainian (uk)
Inventor
Дейвід Ендрю Левіс
Браян Джон Міакін
Мауріціо Дельканале
Фаусто Піветті
Original Assignee
КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36490097&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA92732(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. filed Critical КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.
Publication of UA92732C2 publication Critical patent/UA92732C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Изобретение касается аэрозольных растворимых композиций для применения в аэрозольных ингаляторах, которые содержат, по крайней мере, один активный ингредиент, выбранный из 20-кетостероидов, гидрофлуоркарбоновый пропелент и сорастворитель, стабилизированные добавлением определенного количества связующего соединения – фосфатной и сульфатной кислот.
UAA200707949A 2005-02-25 2006-02-13 Фармацевтические аэрозольные композиции для ингаляторов под давлением с вымеренными дозами, которые содержат связующее соединение UA92732C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05004233 2005-02-25

Publications (1)

Publication Number Publication Date
UA92732C2 true UA92732C2 (ru) 2010-12-10

Family

ID=36490097

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200707949A UA92732C2 (ru) 2005-02-25 2006-02-13 Фармацевтические аэрозольные композиции для ингаляторов под давлением с вымеренными дозами, которые содержат связующее соединение

Country Status (23)

Country Link
US (1) US8877164B2 (ru)
EP (1) EP1850831B1 (ru)
JP (1) JP5259193B2 (ru)
KR (1) KR101313959B1 (ru)
CN (1) CN101119706B (ru)
AR (2) AR054230A1 (ru)
AU (1) AU2006218177B2 (ru)
BR (1) BRPI0607990A2 (ru)
CA (1) CA2594127C (ru)
EA (1) EA013405B1 (ru)
GE (1) GEP20105040B (ru)
HK (1) HK1116337A1 (ru)
IL (1) IL184449A0 (ru)
MA (1) MA29333B1 (ru)
MX (1) MX2007010396A (ru)
NO (1) NO20074854L (ru)
NZ (1) NZ556376A (ru)
PE (1) PE20061011A1 (ru)
SG (1) SG159550A1 (ru)
TN (1) TNSN07289A1 (ru)
UA (1) UA92732C2 (ru)
WO (1) WO2006089656A2 (ru)
ZA (1) ZA200706870B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005008946D1 (de) * 2004-05-13 2008-09-25 Chiesi Farma Spa Medizinische aerosolformulierungen mit verbesserter chemischer stabilität
GB201200525D0 (en) * 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
RU2519653C1 (ru) * 2013-02-27 2014-06-20 Шолекс Девелопмент Гмбх, Аэрозольный препарат на основе ипратропия бромида для лечения заболеваний органов дыхания
US10034866B2 (en) * 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
US11642372B2 (en) 2020-05-01 2023-05-09 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
US11826382B2 (en) 2020-05-01 2023-11-28 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100312357B1 (ko) * 1992-12-09 2002-04-24 데이비드 이. 프랭크하우저 안정화된약제의에어로졸용액제제
ZA939195B (en) * 1992-12-09 1995-06-08 Boehringer Ingelheim Pharma Stabilized medicinal aerosol solution formulations
AU680967B2 (en) 1993-12-20 1997-08-14 Minnesota Mining And Manufacturing Company Flunisolide aerosol formulations
JPH11507359A (ja) * 1995-06-07 1999-06-29 ローヌ−プーラン ローラー ファーマシューティカルズ インコーポレイテッド 安定化ステロイド組成物
EE03509B2 (et) * 1995-06-27 2015-02-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Stabiilsed ravimikompositsioonid kandegaasita aerosoolide saamiseks
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) * 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
AU2001257621A1 (en) * 2000-05-17 2001-11-26 Chrysalis Technologies, Incorporated Stabilized budesonide solution and method for making same
ME00220B (me) * 2000-05-22 2010-10-10 Chiesi Farm Spa Stabilne farmaceutske formulacije rastvora za inhalatore odmjerene doze pod pritiskom
ME00077B (me) * 2002-03-01 2010-06-10 Chiesi Farm Spa Formoterol najfiniji preparat
US7417051B2 (en) 2002-04-12 2008-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments comprising betamimetics and a novel anticholinergic
WO2003087097A1 (de) 2002-04-12 2003-10-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Arzneimittel enthaltend betamimetika und ein neues anticholinergikum
US20040058950A1 (en) 2002-07-09 2004-03-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors
DE10230769A1 (de) 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und PDE-IV-Inhibitoren
DE10237739A1 (de) 2002-08-17 2004-02-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative Arzneimittel enthaltend ein neues Anticholinergikum in Kombination mit Corticosteroiden und Betamimetika
AU2003291634A1 (en) * 2002-10-08 2004-05-04 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers

Also Published As

Publication number Publication date
IL184449A0 (en) 2007-10-31
NZ556376A (en) 2010-01-29
EP1850831A2 (en) 2007-11-07
EA013405B1 (ru) 2010-04-30
AR054230A1 (es) 2007-06-13
WO2006089656A3 (en) 2006-12-21
KR101313959B1 (ko) 2013-10-02
PE20061011A1 (es) 2006-12-08
HK1116337A1 (en) 2008-12-19
MA29333B1 (fr) 2008-03-03
EP1850831B1 (en) 2015-12-02
CA2594127A1 (en) 2006-08-31
ZA200706870B (en) 2008-11-26
US8877164B2 (en) 2014-11-04
CN101119706B (zh) 2013-04-17
EA200701805A1 (ru) 2008-02-28
SG159550A1 (en) 2010-03-30
AR099963A2 (es) 2016-08-31
WO2006089656A2 (en) 2006-08-31
NO20074854L (no) 2007-09-24
KR20070107002A (ko) 2007-11-06
US20060193785A1 (en) 2006-08-31
BRPI0607990A2 (pt) 2009-10-27
AU2006218177A1 (en) 2006-08-31
JP5259193B2 (ja) 2013-08-07
GEP20105040B (en) 2010-07-12
TNSN07289A1 (en) 2008-12-31
JP2008537729A (ja) 2008-09-25
CN101119706A (zh) 2008-02-06
MX2007010396A (es) 2007-10-19
AU2006218177B2 (en) 2012-04-12
CA2594127C (en) 2013-10-15

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