BRPI0607990A2 - formulação de um aerossol farmacêutico para inaladores dosimetrados pressurizados contendo um agente seqüestrante, uso do agente sequestrante, inalador de dosimetrado pressurizado e método de preenchimento do inalador de aerossol - Google Patents

formulação de um aerossol farmacêutico para inaladores dosimetrados pressurizados contendo um agente seqüestrante, uso do agente sequestrante, inalador de dosimetrado pressurizado e método de preenchimento do inalador de aerossol

Info

Publication number
BRPI0607990A2
BRPI0607990A2 BRPI0607990-3A BRPI0607990A BRPI0607990A2 BR PI0607990 A2 BRPI0607990 A2 BR PI0607990A2 BR PI0607990 A BRPI0607990 A BR PI0607990A BR PI0607990 A2 BRPI0607990 A2 BR PI0607990A2
Authority
BR
Brazil
Prior art keywords
aerosol
sequestering agent
metered dose
inhaler
pressurized metered
Prior art date
Application number
BRPI0607990-3A
Other languages
English (en)
Inventor
David Andrew Lewis
Brian John Meakin
Maurizio Delcanale
Fausto Pivetti
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36490097&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0607990(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of BRPI0607990A2 publication Critical patent/BRPI0607990A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

FORMULAçãO DE UM AEROSSOL FARMACêUTICO PARA INALADORES DOSIMETRADOS PRESSURIZADOS CONTENDO UM AGENTE SEQüESTRANTE, USO DO AGENTE SEQUESTRANTE, INALADOR DE DOSIMETRADO PRESSURIZADO E MéTODO DE PREENCHIMENTO DO INALADOR DE AEROSSOL. Formulação de solução em aerossol para uso em inalador de aerossol que contêm, ao menos, um ingrediente ativo selecionado de um grupo que consiste de 20- cetosteróides e derivados de quinolinona, um propelente contendo hidrofluoroalcano, e um cosolvente, estabilizado pela adição de uma quantidade específica de um agente sequestrante.
BRPI0607990-3A 2005-02-25 2006-02-13 formulação de um aerossol farmacêutico para inaladores dosimetrados pressurizados contendo um agente seqüestrante, uso do agente sequestrante, inalador de dosimetrado pressurizado e método de preenchimento do inalador de aerossol BRPI0607990A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05004233 2005-02-25
PCT/EP2006/001287 WO2006089656A2 (en) 2005-02-25 2006-02-13 Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent

Publications (1)

Publication Number Publication Date
BRPI0607990A2 true BRPI0607990A2 (pt) 2009-10-27

Family

ID=36490097

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0607990-3A BRPI0607990A2 (pt) 2005-02-25 2006-02-13 formulação de um aerossol farmacêutico para inaladores dosimetrados pressurizados contendo um agente seqüestrante, uso do agente sequestrante, inalador de dosimetrado pressurizado e método de preenchimento do inalador de aerossol

Country Status (23)

Country Link
US (1) US8877164B2 (pt)
EP (1) EP1850831B1 (pt)
JP (1) JP5259193B2 (pt)
KR (1) KR101313959B1 (pt)
CN (1) CN101119706B (pt)
AR (2) AR054230A1 (pt)
AU (1) AU2006218177B2 (pt)
BR (1) BRPI0607990A2 (pt)
CA (1) CA2594127C (pt)
EA (1) EA013405B1 (pt)
GE (1) GEP20105040B (pt)
HK (1) HK1116337A1 (pt)
IL (1) IL184449A0 (pt)
MA (1) MA29333B1 (pt)
MX (1) MX2007010396A (pt)
NO (1) NO20074854L (pt)
NZ (1) NZ556376A (pt)
PE (1) PE20061011A1 (pt)
SG (1) SG159550A1 (pt)
TN (1) TNSN07289A1 (pt)
UA (1) UA92732C2 (pt)
WO (1) WO2006089656A2 (pt)
ZA (1) ZA200706870B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005112902A2 (en) * 2004-05-13 2005-12-01 Chiesi Farmaceutici S.P.A. Medicinal aerosol formulation products with improved chemical stability
GB201200525D0 (en) * 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
RU2519653C1 (ru) * 2013-02-27 2014-06-20 Шолекс Девелопмент Гмбх, Аэрозольный препарат на основе ипратропия бромида для лечения заболеваний органов дыхания
US10034866B2 (en) * 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
US11826382B2 (en) 2020-05-01 2023-11-28 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
US11642372B2 (en) 2020-05-01 2023-05-09 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA939195B (en) * 1992-12-09 1995-06-08 Boehringer Ingelheim Pharma Stabilized medicinal aerosol solution formulations
SK280911B6 (sk) * 1992-12-09 2000-09-12 Boehringer Ingelheim Pharmaceuticals, Inc. Farmaceutický prostriedok
DE69424181T2 (de) 1993-12-20 2000-10-19 Minnesota Mining & Mfg Flunisolide aerosolformulierungen
CA2223385A1 (en) * 1995-06-07 1996-12-19 Rhone-Poulenc Rorer Pharmaceuticals Inc. Stabilized steroid compositions
IL122752A (en) * 1995-06-27 2001-07-24 Boehringer Ingelheim Kg Stable preparations for creating propellant-free sprays
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) * 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
AU2001257621A1 (en) * 2000-05-17 2001-11-26 Chrysalis Technologies, Incorporated Stabilized budesonide solution and method for making same
ME00220B (me) * 2000-05-22 2010-10-10 Chiesi Farm Spa Stabilne farmaceutske formulacije rastvora za inhalatore odmjerene doze pod pritiskom
ATE465712T1 (de) * 2002-03-01 2010-05-15 Chiesi Farma Spa Ultrafeine zusammensetzungen von formoterol
DK1497289T3 (da) 2002-04-12 2005-10-24 Boehringer Ingelheim Pharma Lægemiddel indeholdende betamimetika og et nyt anticholinergikum
US7417051B2 (en) * 2002-04-12 2008-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments comprising betamimetics and a novel anticholinergic
DE10230769A1 (de) 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und PDE-IV-Inhibitoren
US20040058950A1 (en) * 2002-07-09 2004-03-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors
DE10237739A1 (de) 2002-08-17 2004-02-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative Arzneimittel enthaltend ein neues Anticholinergikum in Kombination mit Corticosteroiden und Betamimetika
US20040235811A1 (en) * 2002-10-08 2004-11-25 Sepracor Inc. Fatty acid modified forms of glucocorticoids
EP1595531A1 (en) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers

Also Published As

Publication number Publication date
TNSN07289A1 (en) 2008-12-31
SG159550A1 (en) 2010-03-30
CA2594127A1 (en) 2006-08-31
GEP20105040B (en) 2010-07-12
CA2594127C (en) 2013-10-15
AR054230A1 (es) 2007-06-13
WO2006089656A2 (en) 2006-08-31
CN101119706A (zh) 2008-02-06
PE20061011A1 (es) 2006-12-08
EA013405B1 (ru) 2010-04-30
JP5259193B2 (ja) 2013-08-07
JP2008537729A (ja) 2008-09-25
NO20074854L (no) 2007-09-24
MX2007010396A (es) 2007-10-19
EP1850831A2 (en) 2007-11-07
IL184449A0 (en) 2007-10-31
WO2006089656A3 (en) 2006-12-21
ZA200706870B (en) 2008-11-26
MA29333B1 (fr) 2008-03-03
EA200701805A1 (ru) 2008-02-28
NZ556376A (en) 2010-01-29
CN101119706B (zh) 2013-04-17
AR099963A2 (es) 2016-08-31
US20060193785A1 (en) 2006-08-31
EP1850831B1 (en) 2015-12-02
KR20070107002A (ko) 2007-11-06
HK1116337A1 (en) 2008-12-19
KR101313959B1 (ko) 2013-10-02
AU2006218177A1 (en) 2006-08-31
AU2006218177B2 (en) 2012-04-12
US8877164B2 (en) 2014-11-04
UA92732C2 (ru) 2010-12-10

Similar Documents

Publication Publication Date Title
UY29905A1 (es) Formulación farmacéutica de absorción oral y su método de administración
AR059350A1 (es) Formulacion farmaceutica para aerosoles con dos o mas principios activos y al menos una sustancia tensioactiva
JO2381B1 (en) Formulation containing anticholinergic drug for the treatment of chronic obstructive pulmonary disease
DE122011100049I1 (de) Stabile pharmazeutische Losungsformulierungen fur unter Druck stehende Inhaliergerate fur die Verabreichung abgemessener Dosen.
BRPI0607990A2 (pt) formulação de um aerossol farmacêutico para inaladores dosimetrados pressurizados contendo um agente seqüestrante, uso do agente sequestrante, inalador de dosimetrado pressurizado e método de preenchimento do inalador de aerossol
NZ534040A (en) Metered dose inhaler
AR019690A1 (es) Formulacion farmaceutica para aerosoles con dos o mas sustancias activas
WO2007020204A3 (en) Hfc solution formulations for inhalation containing salbutamol hydrochloride or salbutamol citrate
BRPI0507225A2 (pt) formulações estáveis de solução farmacêutica para inaladores pressurizados de dose medida
GB0323684D0 (en) Improvements in or relating to organic compounds
BR112014008602A2 (pt) composição farmacêutica, recipiente vedado, inalador de dosagem medida, métodos para o tratamento de um paciente que sofre ou provavelmente sofre de um distúrbio respiratório, e, método para fabricação de uma composição farmacêutica
CY1118461T1 (el) Φαρμακευτικες συνθεσεις που περιλαμβανουν αναστολεα αρωματασης
WO2006053089A3 (en) Methods and formulations for making pharmaceutical compositions containing bupropion
BRPI0506630A (pt) composição de liberação controlada e método para administrar um medicamento aquoso transmucosal de liberação controlada
AR040450A1 (es) Formulacion superfina de salmeterol
NO20083759L (no) Doserings aerosoler for administrering av farmasoytiske preparater
AR060039A1 (es) Formulaciones novedosas
CR9941A (es) Formacion farmaceutica de absorcion oral y su metodo de administracion
UA90346C2 (ru) Фармацевтическая рецептура для перорального приема и способ введения пациенту
UY30515A1 (es) Formulacion farmaceutica y su uso, y dispositivo de dosificacion controlada que contiene el mismo
TH86643A (th) สูตรผสมสารละลาย hfc ที่มีแซลบูทามอล ไฮโดรคลอไรด์ หรือ แซลบูทามอล ซิเทรท
TH150117A (th) สารผสมตามสูตรเภสัชภัณฑ์แบบแข็งซึ่งสลายตัวช้า
AR062152A1 (es) Formulacion farmaceutica y su uso, y dispositivo de dosificacion controlada que contiene el mismo
UA56756U (ru) Фармацевтическая композиция комплексного действия в виде шипучих таблеток для лечения заболеваний органов дыхания
TW200621314A (en) Methods and formulations for making pharmaceutical compositions containing bupropion

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]