EA200701737A1 - Тартраты и малаты транс-1-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина - Google Patents

Тартраты и малаты транс-1-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина

Info

Publication number
EA200701737A1
EA200701737A1 EA200701737A EA200701737A EA200701737A1 EA 200701737 A1 EA200701737 A1 EA 200701737A1 EA 200701737 A EA200701737 A EA 200701737A EA 200701737 A EA200701737 A EA 200701737A EA 200701737 A1 EA200701737 A1 EA 200701737A1
Authority
EA
Eurasian Patent Office
Prior art keywords
trans
phenilindan
dimetylpiperazine
chlor
phenylindan
Prior art date
Application number
EA200701737A
Other languages
English (en)
Inventor
Оле Нильсен
Хейди Лопес Де Диего
Бенни Банг-Андерсен
Original Assignee
Х. Лундбекк А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38006636&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200701737(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Х. Лундбекк А/С filed Critical Х. Лундбекк А/С
Priority claimed from PCT/DK2006/000087 external-priority patent/WO2006086985A1/en
Publication of EA200701737A1 publication Critical patent/EA200701737A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Abstract

Тартрат и малат транс-1-(6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина, в частности, для медицинского применения, его фармацевтические композиции, включая лечение шизофрении или иных заболеваний, включающих психотические симптомы.
EA200701737A 2005-02-16 2006-02-14 Тартраты и малаты транс-1-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина EA200701737A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500238 2005-02-16
PCT/DK2006/000087 WO2006086985A1 (en) 2005-02-16 2006-02-14 Tartrate and malate salts of trans-1-((1r,3s)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine

Publications (1)

Publication Number Publication Date
EA200701737A1 true EA200701737A1 (ru) 2007-12-28

Family

ID=38006636

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200701737A EA200701737A1 (ru) 2005-02-16 2006-02-14 Тартраты и малаты транс-1-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина

Country Status (7)

Country Link
KR (1) KR20070107043A (ru)
CN (1) CN101119982A (ru)
AR (1) AR053132A1 (ru)
EA (1) EA200701737A1 (ru)
IL (1) IL184531A0 (ru)
TW (1) TW200640891A (ru)
ZA (1) ZA200705461B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0912223A2 (pt) * 2008-05-07 2015-10-06 Lundbeck & Co As H métodos para melhorar funcionamento cognitivo e para tratar uma doença, composto, uso do mesmo, e, composição farmacêutica.
TW201102370A (en) * 2009-07-07 2011-01-16 Lundbeck & Co As H Manufacture of 4-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-3,3-dimethyl piperazine
JP2014501771A (ja) * 2011-01-07 2014-01-23 ハー・ルンドベック・アクチエゼルスカベット ４−（（１ｒ，３ｓ）−６−クロロ−３−フェニル−インダン−１−イル）−１，２，２−トリメチル−ピペラジンと１−（（１ｒ，３ｓ）−６−クロロ−３−フェニル−インダン，１−イル）−３，３−ジメチル−ピペラジンとを分割するための方法

Also Published As

Publication number Publication date
IL184531A0 (en) 2007-10-31
KR20070107043A (ko) 2007-11-06
TW200640891A (en) 2006-12-01
AR053132A1 (es) 2007-04-25
CN101119982A (zh) 2008-02-06
ZA200705461B (en) 2008-09-25

Similar Documents

Publication Publication Date Title
WO2007038459A3 (en) Carboxyamine compounds and their use in the treatment of hdac dependent diseases
EA200801997A1 (ru) Новые соединения
LTC1781298I2 (lt) Farmacinės kompozicijos, turinčios benzoksazino, skirtos respiracinių ligų gydymui
BRPI0509369A (pt) azaindóis úteis como inibidores de jak e outras proteìna cinases
EA200900959A1 (ru) Ингибиторы мек
EA200901486A1 (ru) СОЕДИНЕНИЯ И КОМПОЗИЦИИ, КАК ИНГИБИТОРЫ КИНАЗЫ c-KIT И PDGFR
EA201070247A1 (ru) Ингибиторы протеасом
EA200901373A1 (ru) Аминогетероциклические соединения
EA201000644A1 (ru) Антитела для лечения и профилактики болезни альцгеймера и их применение
EA201690265A3 (ru) Фармацевтические композиции, содержащие замещенные ациланилиды
WO2006086562A3 (en) Phenylazetidinone derivatives
MX2009006704A (es) Derivados de amina triciclicos como inhibidores de proteina de tirosina cinasa.
EA200802213A1 (ru) Способы лечения заболеваний крови
EA201170508A1 (ru) Производные 1-амино-2-циклобутилэтилбороновой кислоты
EA200700333A1 (ru) Терапевтические применения ингибиторов rtp801
EA200800172A1 (ru) 2,4-диаминопиримидины как ингибиторы aurora
NO20082026L (no) Deazapuriner som er nyttige som inhibitorer for Janus-kinaser
NO20074593L (no) Tartrat- og malatsalter av trans-1-(6-klor-3-fenylindan-1-yl)-3,3-dimetylpiperazin
EA200601837A1 (ru) Бензоксазины для лечения заболеваний дыхательных путей
CY1108932T1 (el) Ενωσεις 4-(ετεροκυκλυλ)-βενζολοσουλφοξιμινης για την θεραπευτικη αγωγη φλεγμονωδων ασθενειων
TW200716091A (en) New therapeutic combinations for the treatment or prevention of psychotic disorders
EA200901484A1 (ru) СОЕДИНЕНИЯ И КОМПОЗИЦИИ КАК ИНГИБИТОРЫ КИНАЗЫ c-KIT И PDGFR
DE502006008804D1 (de) Neue, langwirksame betamimetika zur behandlung von atemwegserkrankungen
ATE542804T1 (de) 5-phenyl-pentansäurederivate als matrixmetalloproteinase-inhibitoren zur behandlung von asthma und anderen erkrankungen
NO20083751L (no) Metoder for behandling av kognitive og andre sykdommer