EA200701737A1 - TRANS-1 - ((1R, 3S) -6-CHLOR-3-PHENILINDAN-1-IL) -3,3-DIMETYLPIPERAZINE - Google Patents

TRANS-1 - ((1R, 3S) -6-CHLOR-3-PHENILINDAN-1-IL) -3,3-DIMETYLPIPERAZINE

Info

Publication number
EA200701737A1
EA200701737A1 EA200701737A EA200701737A EA200701737A1 EA 200701737 A1 EA200701737 A1 EA 200701737A1 EA 200701737 A EA200701737 A EA 200701737A EA 200701737 A EA200701737 A EA 200701737A EA 200701737 A1 EA200701737 A1 EA 200701737A1
Authority
EA
Eurasian Patent Office
Prior art keywords
trans
phenilindan
dimetylpiperazine
chlor
phenylindan
Prior art date
Application number
EA200701737A
Other languages
Russian (ru)
Inventor
Оле Нильсен
Хейди Лопес Де Диего
Бенни Банг-Андерсен
Original Assignee
Х. Лундбекк А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38006636&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200701737(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Х. Лундбекк А/С filed Critical Х. Лундбекк А/С
Priority claimed from PCT/DK2006/000087 external-priority patent/WO2006086985A1/en
Publication of EA200701737A1 publication Critical patent/EA200701737A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Тартрат и малат транс-1-(6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина, в частности, для медицинского применения, его фармацевтические композиции, включая лечение шизофрении или иных заболеваний, включающих психотические симптомы.Trans-1- (6-chloro-3-phenylindan-1-yl) -3,3-dimethylpiperazine tartrate and malate, in particular for medical use, its pharmaceutical compositions, including the treatment of schizophrenia or other diseases, including psychotic symptoms.

EA200701737A 2005-02-16 2006-02-14 TRANS-1 - ((1R, 3S) -6-CHLOR-3-PHENILINDAN-1-IL) -3,3-DIMETYLPIPERAZINE EA200701737A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500238 2005-02-16
PCT/DK2006/000087 WO2006086985A1 (en) 2005-02-16 2006-02-14 Tartrate and malate salts of trans-1-((1r,3s)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine

Publications (1)

Publication Number Publication Date
EA200701737A1 true EA200701737A1 (en) 2007-12-28

Family

ID=38006636

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200701737A EA200701737A1 (en) 2005-02-16 2006-02-14 TRANS-1 - ((1R, 3S) -6-CHLOR-3-PHENILINDAN-1-IL) -3,3-DIMETYLPIPERAZINE

Country Status (7)

Country Link
KR (1) KR20070107043A (en)
CN (1) CN101119982A (en)
AR (1) AR053132A1 (en)
EA (1) EA200701737A1 (en)
IL (1) IL184531A0 (en)
TW (1) TW200640891A (en)
ZA (1) ZA200705461B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ589571A (en) * 2008-05-07 2012-07-27 Lundbeck & Co As H Method for treating cognitive deficits using trans-4-((1r,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine
TW201102370A (en) * 2009-07-07 2011-01-16 Lundbeck & Co As H Manufacture of 4-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-3,3-dimethyl piperazine
CA2823103A1 (en) * 2011-01-07 2012-07-12 H. Lundbeck A/S Method for resolution of 4-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-3,3-dimethyl-piperazine

Also Published As

Publication number Publication date
KR20070107043A (en) 2007-11-06
TW200640891A (en) 2006-12-01
AR053132A1 (en) 2007-04-25
IL184531A0 (en) 2007-10-31
ZA200705461B (en) 2008-09-25
CN101119982A (en) 2008-02-06

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