AR053132A1 - TARTRATE AND MALATE SALTS OF TRANS-1- (6-CHLORO-3-FENILIDAN-1-IL) -3,3-DIMETHYLIPIPERAZINE - Google Patents

TARTRATE AND MALATE SALTS OF TRANS-1- (6-CHLORO-3-FENILIDAN-1-IL) -3,3-DIMETHYLIPIPERAZINE

Info

Publication number
AR053132A1
AR053132A1 ARP060100518A ARP060100518A AR053132A1 AR 053132 A1 AR053132 A1 AR 053132A1 AR P060100518 A ARP060100518 A AR P060100518A AR P060100518 A ARP060100518 A AR P060100518A AR 053132 A1 AR053132 A1 AR 053132A1
Authority
AR
Argentina
Prior art keywords
trans
chloro
tartrate
fenilidan
dimethylipiperazine
Prior art date
Application number
ARP060100518A
Other languages
Spanish (es)
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38006636&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR053132(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of AR053132A1 publication Critical patent/AR053132A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Composiciones farmacéuticas que los contienen, usos para tratar esquizofrenia u otros síntomas psicoticos y método de preparacion. Reivindicacion 1: Una sal de malato del compuesto 1, donde el compuesto 1 (trans-1-((1R,3S)-6-cloro-3-fenilindan-1- il)-3,3-dimetilpiperazina) tiene la formula (1). Reivindicacion 9: Una sal de tartrato del compuesto 1, donde el compuesto 1 (trans-1-((1R,3S)-6-cloro-3-fenilindan-1-il)-3,3-dimetilpiperazina) tiene la formula (1).Pharmaceutical compositions containing them, uses to treat schizophrenia or other psychotic symptoms and method of preparation. Claim 1: A malate salt of compound 1, wherein compound 1 (trans-1 - ((1R, 3S) -6-chloro-3-phenylindan-1- yl) -3,3-dimethylpiperazine) has the formula ( one). Claim 9: A tartrate salt of compound 1, wherein compound 1 (trans-1 - ((1R, 3S) -6-chloro-3-phenylindan-1-yl) -3,3-dimethylpiperazine) has the formula ( one).

ARP060100518A 2005-02-16 2006-02-14 TARTRATE AND MALATE SALTS OF TRANS-1- (6-CHLORO-3-FENILIDAN-1-IL) -3,3-DIMETHYLIPIPERAZINE AR053132A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200500238 2005-02-16

Publications (1)

Publication Number Publication Date
AR053132A1 true AR053132A1 (en) 2007-04-25

Family

ID=38006636

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060100518A AR053132A1 (en) 2005-02-16 2006-02-14 TARTRATE AND MALATE SALTS OF TRANS-1- (6-CHLORO-3-FENILIDAN-1-IL) -3,3-DIMETHYLIPIPERAZINE

Country Status (7)

Country Link
KR (1) KR20070107043A (en)
CN (1) CN101119982A (en)
AR (1) AR053132A1 (en)
EA (1) EA200701737A1 (en)
IL (1) IL184531A0 (en)
TW (1) TW200640891A (en)
ZA (1) ZA200705461B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009243813B2 (en) * 2008-05-07 2014-05-29 H. Lundbeck A/S Method for treating cognitive deficits
TW201102370A (en) * 2009-07-07 2011-01-16 Lundbeck & Co As H Manufacture of 4-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-3,3-dimethyl piperazine
JP2014501771A (en) * 2011-01-07 2014-01-23 ハー・ルンドベック・アクチエゼルスカベット 4-((1R, 3S) -6-chloro-3-phenyl-indan-1-yl) -1,2,2-trimethyl-piperazine and 1-((1R, 3S) -6-chloro-3-phenyl -Method for resolution of indan, 1-yl) -3,3-dimethyl-piperazine

Also Published As

Publication number Publication date
EA200701737A1 (en) 2007-12-28
ZA200705461B (en) 2008-09-25
TW200640891A (en) 2006-12-01
KR20070107043A (en) 2007-11-06
IL184531A0 (en) 2007-10-31
CN101119982A (en) 2008-02-06

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