EA200501229A1 - 6-замещённые имидазопиразины - Google Patents
6-замещённые имидазопиразиныInfo
- Publication number
- EA200501229A1 EA200501229A1 EA200501229A EA200501229A EA200501229A1 EA 200501229 A1 EA200501229 A1 EA 200501229A1 EA 200501229 A EA200501229 A EA 200501229A EA 200501229 A EA200501229 A EA 200501229A EA 200501229 A1 EA200501229 A1 EA 200501229A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- substituted imidazopyrazines
- imidazopyrazines
- substituted
- designations
- substituents
- Prior art date
Links
- -1 6-Substituted Imidazopyrazines Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03003652 | 2003-02-18 | ||
| PCT/EP2004/050135 WO2004074289A1 (en) | 2003-02-18 | 2004-02-16 | 6-substituted imidazopyrazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200501229A1 true EA200501229A1 (ru) | 2006-04-28 |
Family
ID=32892854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200501229A EA200501229A1 (ru) | 2003-02-18 | 2004-02-16 | 6-замещённые имидазопиразины |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20060148796A1 (enExample) |
| EP (1) | EP1599481A1 (enExample) |
| JP (1) | JP2006517951A (enExample) |
| KR (1) | KR20050100396A (enExample) |
| CN (1) | CN1747956A (enExample) |
| AR (1) | AR043002A1 (enExample) |
| AU (1) | AU2004213177A1 (enExample) |
| BR (1) | BRPI0407390A (enExample) |
| CA (1) | CA2516021A1 (enExample) |
| EA (1) | EA200501229A1 (enExample) |
| HR (1) | HRP20050794A2 (enExample) |
| IS (1) | IS8015A (enExample) |
| MX (1) | MXPA05008582A (enExample) |
| NO (1) | NO20054199L (enExample) |
| PL (1) | PL376466A1 (enExample) |
| RS (1) | RS20050619A (enExample) |
| TW (1) | TW200504068A (enExample) |
| WO (1) | WO2004074289A1 (enExample) |
| ZA (1) | ZA200505670B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA024140B1 (ru) * | 2008-12-08 | 2016-08-31 | Джилид Коннектикут, Инк. | Имидазопиразиновые ингибиторы тирозинкиназы syk |
| US10093684B2 (en) | 2008-12-08 | 2018-10-09 | Gilead Connecticut, Inc. | Substituted imidazo[1,2-a]pyrazines as Syk inhibitors |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007028051A2 (en) | 2005-09-02 | 2007-03-08 | Abbott Laboratories | Novel imidazo based heterocycles |
| CA2654202A1 (en) * | 2006-06-06 | 2007-12-21 | Schering Corporation | Imidazopyrazines as protein kinase inhibitors |
| US20090175852A1 (en) | 2006-06-06 | 2009-07-09 | Schering Corporation | Imidazopyrazines as protein kinase inhibitors |
| WO2008059373A1 (en) * | 2006-11-17 | 2008-05-22 | Raqualia Pharma Inc. | Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists |
| GB0716292D0 (en) | 2007-08-21 | 2007-09-26 | Biofocus Dpi Ltd | Imidazopyrazine compounds |
| ES2530449T3 (es) | 2010-03-11 | 2015-03-02 | Gilead Connecticut Inc | Inhibidores de Syk de imidazopiridinas |
| CN116178295A (zh) * | 2023-01-28 | 2023-05-30 | 山东亿盛实业股份有限公司 | 一种苯唑草酮代谢物t283的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4725601A (en) * | 1985-06-04 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers |
| JPH07242666A (ja) * | 1994-03-08 | 1995-09-19 | Fujisawa Pharmaceut Co Ltd | 複素環化合物 |
| SE9704404D0 (sv) * | 1997-11-28 | 1997-11-28 | Astra Ab | New compounds |
| SE9801526D0 (sv) * | 1998-04-29 | 1998-04-29 | Astra Ab | New compounds |
| EP1363702A4 (en) * | 2001-01-30 | 2007-08-22 | Cytopia Pty Ltd | PROCESS FOR INHIBITING KINASES |
-
2004
- 2004-02-02 AR ARP040100313A patent/AR043002A1/es not_active Application Discontinuation
- 2004-02-11 TW TW093103176A patent/TW200504068A/zh unknown
- 2004-02-16 CA CA002516021A patent/CA2516021A1/en not_active Abandoned
- 2004-02-16 RS YUP-2005/0619A patent/RS20050619A/sr unknown
- 2004-02-16 CN CNA200480003928XA patent/CN1747956A/zh active Pending
- 2004-02-16 KR KR1020057014835A patent/KR20050100396A/ko not_active Withdrawn
- 2004-02-16 WO PCT/EP2004/050135 patent/WO2004074289A1/en not_active Ceased
- 2004-02-16 MX MXPA05008582A patent/MXPA05008582A/es not_active Application Discontinuation
- 2004-02-16 AU AU2004213177A patent/AU2004213177A1/en not_active Abandoned
- 2004-02-16 JP JP2006502029A patent/JP2006517951A/ja not_active Withdrawn
- 2004-02-16 US US10/545,190 patent/US20060148796A1/en not_active Abandoned
- 2004-02-16 BR BR0407390-8A patent/BRPI0407390A/pt not_active IP Right Cessation
- 2004-02-16 EA EA200501229A patent/EA200501229A1/ru unknown
- 2004-02-16 PL PL04376466A patent/PL376466A1/xx not_active Application Discontinuation
- 2004-02-16 EP EP04711383A patent/EP1599481A1/en not_active Withdrawn
- 2004-02-16 HR HR20050794A patent/HRP20050794A2/xx not_active Application Discontinuation
-
2005
- 2005-07-14 ZA ZA200505670A patent/ZA200505670B/en unknown
- 2005-09-08 IS IS8015A patent/IS8015A/is unknown
- 2005-09-09 NO NO20054199A patent/NO20054199L/no not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA024140B1 (ru) * | 2008-12-08 | 2016-08-31 | Джилид Коннектикут, Инк. | Имидазопиразиновые ингибиторы тирозинкиназы syk |
| US10093684B2 (en) | 2008-12-08 | 2018-10-09 | Gilead Connecticut, Inc. | Substituted imidazo[1,2-a]pyrazines as Syk inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0407390A (pt) | 2006-02-07 |
| CN1747956A (zh) | 2006-03-15 |
| TW200504068A (en) | 2005-02-01 |
| AR043002A1 (es) | 2005-07-13 |
| ZA200505670B (en) | 2006-04-26 |
| RS20050619A (sr) | 2007-09-21 |
| US20060148796A1 (en) | 2006-07-06 |
| NO20054199L (no) | 2005-11-17 |
| WO2004074289A1 (en) | 2004-09-02 |
| JP2006517951A (ja) | 2006-08-03 |
| AU2004213177A1 (en) | 2004-09-02 |
| MXPA05008582A (es) | 2005-11-04 |
| KR20050100396A (ko) | 2005-10-18 |
| NO20054199D0 (no) | 2005-09-09 |
| CA2516021A1 (en) | 2004-09-02 |
| IS8015A (is) | 2005-09-08 |
| EP1599481A1 (en) | 2005-11-30 |
| PL376466A1 (en) | 2005-12-27 |
| HRP20050794A2 (hr) | 2006-12-31 |
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