WO2006037748A8 - Substituted tricyclic benzimidazoles - Google Patents

Substituted tricyclic benzimidazoles

Info

Publication number
WO2006037748A8
WO2006037748A8 PCT/EP2005/054898 EP2005054898W WO2006037748A8 WO 2006037748 A8 WO2006037748 A8 WO 2006037748A8 EP 2005054898 W EP2005054898 W EP 2005054898W WO 2006037748 A8 WO2006037748 A8 WO 2006037748A8
Authority
WO
WIPO (PCT)
Prior art keywords
substituted tricyclic
tricyclic benzimidazoles
benzimidazoles
gastric
substituted
Prior art date
Application number
PCT/EP2005/054898
Other languages
French (fr)
Other versions
WO2006037748A1 (en
Inventor
Wilm Buhr
Peter Jan Zimmermann
Christof Brehm
Andreas Palmer
M Vittoria Chiesa
Wolfgang-Alexander Simon
Stefan Postius
Wolfgang Kromer
Original Assignee
Altana Pharma Ag
Wilm Buhr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag, Wilm Buhr filed Critical Altana Pharma Ag
Priority to AU2005291284A priority Critical patent/AU2005291284A1/en
Priority to EP05799049A priority patent/EP1797089A1/en
Priority to CA002582256A priority patent/CA2582256A1/en
Publication of WO2006037748A1 publication Critical patent/WO2006037748A1/en
Publication of WO2006037748A8 publication Critical patent/WO2006037748A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Abstract

The invention relates to substituted tricyclic benzimidazoles of the formula (1) in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
PCT/EP2005/054898 2004-10-01 2005-09-29 Substituted tricyclic benzimidazoles WO2006037748A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2005291284A AU2005291284A1 (en) 2004-10-01 2005-09-29 Substituted tricyclic benzimidazoles
EP05799049A EP1797089A1 (en) 2004-10-01 2005-09-29 Substituted tricyclic benzimidazoles
CA002582256A CA2582256A1 (en) 2004-10-01 2005-09-29 Substituted tricyclic benzimidazoles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04104838 2004-10-01
EP04104838.0 2004-10-01

Publications (2)

Publication Number Publication Date
WO2006037748A1 WO2006037748A1 (en) 2006-04-13
WO2006037748A8 true WO2006037748A8 (en) 2006-11-30

Family

ID=34929651

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/054898 WO2006037748A1 (en) 2004-10-01 2005-09-29 Substituted tricyclic benzimidazoles

Country Status (4)

Country Link
EP (1) EP1797089A1 (en)
AU (1) AU2005291284A1 (en)
CA (1) CA2582256A1 (en)
WO (1) WO2006037748A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102470126A (en) 2009-07-09 2012-05-23 拉夸里亚创药株式会社 Acid pump antagonist for treatment of diseases associated with abnormal gastrointestinal movement
CN112358450A (en) * 2020-11-19 2021-02-12 南京艾康生物科技有限公司 Synthesis method of 4- (benzyloxy) -2-methyl-1H-benzo [ d ] imidazole-6-carboxylic acid

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9602286D0 (en) * 1996-06-10 1996-06-10 Astra Ab New compounds
HUP0001555A3 (en) * 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
ATE386742T1 (en) * 1998-11-03 2008-03-15 Nycomed Gmbh IMIDAZONAPHTHYRIDINES
ATE240956T1 (en) * 1999-04-17 2003-06-15 Altana Pharma Ag HALOALKOXY-IMIDAZONAPHTHYRIDINES
BR0109542A (en) * 2000-03-29 2003-06-10 Altana Pharma Ag Alkylated imidazopyrine derivatives
PL365116A1 (en) * 2000-03-29 2004-12-27 Altana Pharma Ag Prodrugs of imidazopyridine derivatives
NZ525281A (en) * 2000-10-25 2004-11-26 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors

Also Published As

Publication number Publication date
WO2006037748A1 (en) 2006-04-13
AU2005291284A1 (en) 2006-04-13
CA2582256A1 (en) 2006-04-13
EP1797089A1 (en) 2007-06-20

Similar Documents

Publication Publication Date Title
TW200504031A (en) 6-substituted benzimidazoles
NO20055033L (en) Cyclic benzimidazoles
TW200616971A (en) Condensed tricyclic benzimidazoles
TW200602326A (en) Tricyclic imidazopyridines
NO20054199L (en) 6-substituted imidazopyrazines
NO20052857L (en) 8-substituted imidazopyridines
HK1066213A1 (en) Tricyclic imidazopyridines.
WO2004110990A3 (en) Imidazothiazoles and imidazoxazole derivatives as inhibitors of p38
NO20063220L (en) Tricyclic imidazopyridines for use as gastric secretion inhibitors
WO2005121139A8 (en) Substituted tricyclic benzimidazoles
EA200300478A1 (en) HALF-DISPOSED IMIDAZOPIRIDINE AS GAS-INHIBITOR INHIBITORS
TW200600502A (en) Novel 6-substituted benzimidazoles
WO2006037748A8 (en) Substituted tricyclic benzimidazoles
TW200720273A (en) Pharmaceutically active spiro-benzimidazoles
WO2005058893A8 (en) Tricyclic benzimidazoles
WO2006061380A3 (en) SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS INHIBITORS OF GASTRIC ACID SECRETION
TW200630373A (en) Difluoro-substituted imidazopyridines
WO2008095912A3 (en) Enantiopure pharmacologically active tricyclic benzimidazoles
WO2008071766A3 (en) Spiro-indene substituted imidazonaphythyridine and pyranoimidazopyridine derivatives as inhibitors of gastric acid secretion
TW200603801A (en) Novel dialkoxy-imidazopyridines
TW200613301A (en) Novel amino-halogen-imidazopyridines
TW200716637A (en) Pharmaceutically active spiro-imidazopyridines
WO2008017466A8 (en) Pharmaceutically active tetrahydroisoquinoline-substituted benzimidazole derivatives

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2582256

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2005799049

Country of ref document: EP

NENP Non-entry into the national phase in:

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2005291284

Country of ref document: AU

ENP Entry into the national phase in:

Ref document number: 2005291284

Country of ref document: AU

Date of ref document: 20050929

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2005799049

Country of ref document: EP