EA199900502A1 - 8-азабицикло[3.2.1]октан-, 8-азабицикло[3.2.1]окт-6-ен-, 9-азабицикло[3.3.1]нонан-, 9-аза-3-оксабицикло[3.3.1]нонан- и 9-аза-3-тиабицикло[3.3.1]нонанпроизводные, их получение и их применение в качестве инсектицидов - Google Patents

8-азабицикло[3.2.1]октан-, 8-азабицикло[3.2.1]окт-6-ен-, 9-азабицикло[3.3.1]нонан-, 9-аза-3-оксабицикло[3.3.1]нонан- и 9-аза-3-тиабицикло[3.3.1]нонанпроизводные, их получение и их применение в качестве инсектицидов

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Publication number
EA199900502A1
EA199900502A1 EA199900502A EA199900502A EA199900502A1 EA 199900502 A1 EA199900502 A1 EA 199900502A1 EA 199900502 A EA199900502 A EA 199900502A EA 199900502 A EA199900502 A EA 199900502A EA 199900502 A1 EA199900502 A1 EA 199900502A1
Authority
EA
Eurasian Patent Office
Prior art keywords
group
cyano
nonan
azabicyclo
aza
Prior art date
Application number
EA199900502A
Other languages
English (en)
Inventor
Кристофер Джон Урх
Теренс Льюис
Рэймонд Лео Санли
Раймонд Сэлмон
Кристофер Ричард Эйлес Годфри
Кристофер Ян Брайтвелл
Мэтью Брайан Хотсон
Original Assignee
Зенека Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9624611.1A external-priority patent/GB9624611D0/en
Priority claimed from GBGB9624516.2A external-priority patent/GB9624516D0/en
Priority claimed from GBGB9624614.5A external-priority patent/GB9624614D0/en
Application filed by Зенека Лимитед filed Critical Зенека Лимитед
Publication of EA199900502A1 publication Critical patent/EA199900502A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/16—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Abstract

Настоящее изобретение относится к соединению формулы (I)где A представляет бидентатную группу формулы -CH-X-CH- (где X представляет метилен, серу или кислород), X'C=CY или X'WC-CYZ (где X', W, Y и Z представляют, независимо, водород, гидрокси, ацилокси, алкокси, алкилсилилокси, циано или галоген, или X' и W или Y и Z вместе с углеродом, к которому они присоединены, образуют карбонильную группу), при условии, что A не является CH-CH; Ar представляет необязательно замещенный фенил или 5- или 6-членную гетероциклическую кольцевую систему, содержащую от 1 до 3 гетероатомов, выбранных по отдельности из атомов азота, кислорода и серы, и, по меньшей мере, одну ненасыщенность (двойную связь) между соседними атомами в кольце, причем указанное гетероциклическое кольцо необязательно конденсировано с бензольным кольцом, где заместители, если они присутствуют, выбраны из атомов галогена, циано, алкила, алкенила, алкинила, алкокси, галогеналкила, галогеналкенила, алкилтио- и алкиламиногрупп, любая из которых содержит до шести атомов углерода; R представляет водород или циано или группу, выбранную из алкила, арила, гетероарила, аралкила, гетероарилалкила, алкенила, аралкенила, алкинила, алкоксикарбонила, алкансульфонила, аренсульфонила, алкенилоксикарбонила, аралкилоксикарбонила, арилоксикарбонила, гетероциклилалкила, карбамила, дитиокарбоксила или X"R(где X" представляет кислород или группу NR), при условии, что когда R представляет алкенил, аралкенил или алкинил, указанная группа не содержит ненасыщенного атома углерода, непосредственно связанного с азотом кольца формулы (I); Rпредставляет водород, циано, гидрокси, алкил, алкокси, амино, нитро, изоцианато, ациламино, гидроксиалкил, необязательно замещенный
EA199900502A 1996-11-26 1997-11-06 8-азабицикло[3.2.1]октан-, 8-азабицикло[3.2.1]окт-6-ен-, 9-азабицикло[3.3.1]нонан-, 9-аза-3-оксабицикло[3.3.1]нонан- и 9-аза-3-тиабицикло[3.3.1]нонанпроизводные, их получение и их применение в качестве инсектицидов EA199900502A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9624611.1A GB9624611D0 (en) 1996-11-26 1996-11-26 Bicyclic amine compounds
GBGB9624516.2A GB9624516D0 (en) 1996-11-26 1996-11-26 Bicyclic amine derivatives
GBGB9624614.5A GB9624614D0 (en) 1996-11-26 1996-11-26 Bicyclic amine derivatives
PCT/GB1997/003054 WO1998025924A1 (en) 1996-11-26 1997-11-06 8-azabicyclo[3.2.1]octane-, 8-azabicyclo[3.2.1]oct-6-ene-, 9-azabicyclo[3.3.1]nonane-, 9-aza-3-oxabicyclo[3.3.1]nonane- and 9-aza-3-thiabicyclo[3.3.1]nonane derivatives, their preparation and their use as insecticides

Publications (1)

Publication Number Publication Date
EA199900502A1 true EA199900502A1 (ru) 2000-02-28

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900502A EA199900502A1 (ru) 1996-11-26 1997-11-06 8-азабицикло[3.2.1]октан-, 8-азабицикло[3.2.1]окт-6-ен-, 9-азабицикло[3.3.1]нонан-, 9-аза-3-оксабицикло[3.3.1]нонан- и 9-аза-3-тиабицикло[3.3.1]нонанпроизводные, их получение и их применение в качестве инсектицидов

Country Status (32)

Country Link
US (4) US5968947A (ru)
EP (1) EP0944627B1 (ru)
JP (1) JP2001506989A (ru)
KR (1) KR20000069122A (ru)
CN (1) CN1245499A (ru)
AP (1) AP9901538A0 (ru)
AR (1) AR010651A1 (ru)
AT (1) ATE259806T1 (ru)
AU (1) AU719147B2 (ru)
BG (1) BG103517A (ru)
BR (1) BR9713136A (ru)
CA (1) CA2271749A1 (ru)
CO (1) CO5040071A1 (ru)
CZ (1) CZ184199A3 (ru)
DE (1) DE69727694T2 (ru)
EA (1) EA199900502A1 (ru)
EG (1) EG21556A (ru)
ES (1) ES2216131T3 (ru)
GT (1) GT199700124A (ru)
HU (1) HUP0000582A3 (ru)
ID (1) ID22349A (ru)
IL (1) IL130058A0 (ru)
MA (1) MA24405A1 (ru)
NZ (1) NZ335422A (ru)
OA (1) OA11052A (ru)
SI (1) SI20020A (ru)
SK (1) SK69299A3 (ru)
TN (1) TNSN97190A1 (ru)
TR (1) TR199901704T2 (ru)
TW (1) TW370451B (ru)
UY (1) UY24793A1 (ru)
WO (1) WO1998025924A1 (ru)

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SK69299A3 (en) 2000-01-18
US6291474B1 (en) 2001-09-18
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NZ335422A (en) 2000-10-27
US20020061913A1 (en) 2002-05-23
ATE259806T1 (de) 2004-03-15
OA11052A (en) 2003-03-12
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US6177442B1 (en) 2001-01-23
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SI20020A (sl) 2000-02-29
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