EA199800797A1 - Новые мостиковые циклические аминокислоты как фармацевтически применимые вещества - Google Patents

Новые мостиковые циклические аминокислоты как фармацевтически применимые вещества

Info

Publication number
EA199800797A1
EA199800797A1 EA199800797A EA199800797A EA199800797A1 EA 199800797 A1 EA199800797 A1 EA 199800797A1 EA 199800797 A EA199800797 A EA 199800797A EA 199800797 A EA199800797 A EA 199800797A EA 199800797 A1 EA199800797 A1 EA 199800797A1
Authority
EA
Eurasian Patent Office
Prior art keywords
amino acids
cyclic amino
pct
pharmatic
mostic
Prior art date
Application number
EA199800797A
Other languages
English (en)
Other versions
EA001214B1 (ru
Inventor
Дейвид Кристофер Орвелл
Джастин С. Брайэнс
Клер О. Нин
Эндру И. Моррелл
Джильс С. Ретклифф
Original Assignee
Варнер-Ламберт Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Варнер-Ламберт Компани filed Critical Варнер-Ламберт Компани
Publication of EA199800797A1 publication Critical patent/EA199800797A1/ru
Publication of EA001214B1 publication Critical patent/EA001214B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/46—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing nine carbon atoms

Abstract

Описаны новые циклические аминокислоты формулы I, являющиеся полезными в качестве средств при лечении эпилепсии, приступов обморочного состояния, гипокинезии, черепно-мозговых расстройств, нейродегенеративных расстройств, депрессии, тревожного состояния, панического состояния, боли и нейропатологических расстройств. Описаны способ получения и промежуточные соединения, применимые для получения этих веществ.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199800797A 1996-03-14 1997-02-18 Новые мостиковые циклические аминокислоты как фармацевтически применимые вещества EA001214B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1343396P 1996-03-14 1996-03-14
PCT/US1997/002401 WO1997033859A1 (en) 1996-03-14 1997-02-18 Novel bridged cyclic amino acids as pharmaceutical agents

Publications (2)

Publication Number Publication Date
EA199800797A1 true EA199800797A1 (ru) 1999-04-29
EA001214B1 EA001214B1 (ru) 2000-12-25

Family

ID=21759944

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800797A EA001214B1 (ru) 1996-03-14 1997-02-18 Новые мостиковые циклические аминокислоты как фармацевтически применимые вещества

Country Status (18)

Country Link
US (1) US6020370A (ru)
EP (1) EP0888285B1 (ru)
JP (1) JP2000506862A (ru)
KR (1) KR100487032B1 (ru)
AT (1) ATE210629T1 (ru)
AU (1) AU731279B2 (ru)
BR (1) BR9708180A (ru)
CZ (1) CZ287598A3 (ru)
DE (1) DE69709070T2 (ru)
EA (1) EA001214B1 (ru)
ES (1) ES2169848T3 (ru)
IL (1) IL125364A0 (ru)
NO (1) NO984204D0 (ru)
NZ (1) NZ331142A (ru)
PL (1) PL185990B1 (ru)
SK (1) SK282848B6 (ru)
WO (1) WO1997033859A1 (ru)
ZA (1) ZA972199B (ru)

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Also Published As

Publication number Publication date
NO984204L (no) 1998-09-11
PL185990B1 (pl) 2003-09-30
NO984204D0 (no) 1998-09-11
DE69709070D1 (de) 2002-01-24
CZ287598A3 (cs) 1999-02-17
SK124898A3 (en) 1999-02-11
KR19990087755A (ko) 1999-12-27
IL125364A0 (en) 1999-03-12
WO1997033859A1 (en) 1997-09-18
ZA972199B (en) 1997-09-17
NZ331142A (en) 2001-04-27
AU731279B2 (en) 2001-03-29
EP0888285A1 (en) 1999-01-07
DE69709070T2 (de) 2002-06-20
US6020370A (en) 2000-02-01
EP0888285B1 (en) 2001-12-12
BR9708180A (pt) 1999-07-27
JP2000506862A (ja) 2000-06-06
ES2169848T3 (es) 2002-07-16
AU2127197A (en) 1997-10-01
EA001214B1 (ru) 2000-12-25
KR100487032B1 (ko) 2005-12-21
SK282848B6 (sk) 2002-12-03
PL328800A1 (en) 1999-02-15
ATE210629T1 (de) 2001-12-15

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